Results 131 to 140 of about 48,614 (253)

Discovering Legacies: Fathers, Sons, Masculinities, and Equity Within Families

Journal of Family Theory &Review, EarlyView.
ABSTRACT In this article, I examine how personal experiences within my family and my homeplace communities have shaped 20 years of basic and applied research, as well as theorizing, on fathering and masculinities. I focus on how my practice of reflexive research has led me to discover legacies of masculinities across generations of my own family ...
Kevin Roy
wiley   +1 more source

Orphan nuclear receptors as regulators of intratumoral androgen biosynthesis in castration-resistant prostate cancer. [PDF]

Oncogene, 2021
Zhou J, Wang Y, Wu D, Wang S, Chen Z, Xiang S, Chan FL.   +6 more
europepmc   +1 more source

GcrR in Streptococcus mutans Inhibits the Morphological Transition of Candida albicans Through Ras1–cAMP/PKA Pathway in the Cross‐Kingdom Biofilms

Molecular Oral Microbiology, EarlyView.
ABSTRACT The dual‐species biofilms formed by Streptococcus mutans and Candida albicans exhibit enhanced cariogenic potential due to the production of extracellular polysaccharides (EPSs). The response regulator GcrR in S. mutans negatively regulates EPS synthesis, but its impact on dual‐species biofilms remains unclear.
Bin Zhang, Shihao Hou, Anqi Zhang, Jielin Yang, Wenjiao Zhang, Shijie Zhu, Hong Chen, Ruizhe Huang   +7 more
wiley   +1 more source

A New Concept of “Kim Jong Un Partizan” Discourse and Authoritarian Durability in North Korea

Pacific Focus, EarlyView.
ABSTRACT How does the North Korean regime secure elite loyalty without institutional transparency or material redistribution? While existing studies have examined the use of Partizan narratives under Kim Il Sung and Kim Jong Il, this paper argues that Kim Jong Un introduces a significant discursive shift: the invention of “Kim Jong Un Partizans.” This ...
Sohee Hwang
wiley   +1 more source

Prolonged exposure to artificial light and carcinogenesis: A systematic review of oncostatic mechanisms associated with melatonin pathways

Photochemistry and Photobiology, EarlyView.
Exposure to artificial light at night (ALAN), particularly at blue wavelengths, disrupts circadian rhythms by suppressing melatonin, thereby increasing cancer susceptibility. This systematic review consolidates evidence linking prolonged ALAN exposure to an elevated risk of breast and prostate tumors.
Gabriel Barboza, Jêmina Oliveira, Antônio Ferreira, Renan Lopes, Marli Cupertino   +4 more
wiley   +1 more source

Microarray Gene Expression Analysis of Lesional Skin in Canine Vesicular Cutaneous Lupus Erythematosus (VCLE)

Veterinary Dermatology, EarlyView.
Background: Vesicular cutaneous lupus erythematosus (VCLE) is a rare autoimmune disease in dogs and is considered the canine counterpart of human subacute cutaneous lupus erythematosus (SCLE). However, the molecular mechanisms underlying VCLE remain incompletely defined.
Treasa Keating, Lauren Stranahan, Dominique Wiener, M. Kelly Keating, Renato Leon, Frane Banovic   +5 more
wiley   +1 more source

TMEM16A chloride channels in the female reproductive tract and their role in normal and dysfunctional pregnancy and labour

The Journal of Physiology, EarlyView.
Abstract figure legend TMEM16A plays a pivotal role in setting the duration of the action potential plateau in human uterine smooth muscle. An increase in TMEM16A expression in labour underpins a lengthening of the plateau and this provides time for the contraction to become larger and longer, important for timely successful labour.
Helena C. Parkington, Harold A. Coleman, Penelope M. Sheehan, Shaun P. Brennecke, Marianne Tare   +4 more
wiley   +1 more source

Cannabinoid exposure during pregnancy: Cardiorespiratory effects and offspring outcomes

The Journal of Physiology, EarlyView.
Abstract figure legend Prenatal exposure to cannabinoids has been investigated across human and animal studies to understand its impact on physiological development. Evidence suggests that early‐life cannabinoid exposure influence multiple developmental processes, extending beyond neurodevelopmental outcomes to potentially affect placental function ...
Luis Gustavo A. Patrone, Luciane H. Gargaglioni   +1 more
wiley   +1 more source

The multiple mechanisms of NR4A2 in neurological disorders and advances in targeted therapy research

Neurobiology of Disease
Nuclear Receptor Subfamily 4 Group A Member 2 (NR4A2) is a transcription factor widely distributed in the central nervous system, playing a crucial regulatory role in various physiological and pathological processes, including dopaminergic neuronal ...
Kexin Duan, Caiyun Yang, Da Gao, Mengzhu Li, Mengxuan Chen, Haiyan Li, Weicong Zeng, Lijun Zhao, Meiling Zhu   +8 more
doaj   +1 more source

Physiological and anatomical determinants of placental drug transfer

The Journal of Physiology, EarlyView.
Abstract figure legend Fetal exposure to pharmaceuticals and their subsequent clearance back to the maternal circulation are governed by placental transfer. Passive diffusion down a maternal‐to‐fetal concentration gradient is the primary route of fetal drug exposure, with specific compounds undergoing transporter‐mediated transfer.
Rohan M. Lewis, Anandita Umapathy, Jane K. Cleal, Bram G. Sengers   +3 more
wiley   +1 more source