Results 21 to 30 of about 11,507 (279)

Therapeutic and Prophylactic Drugs to Treat Orthopoxvirus Infections [PDF]

Future Virology, 2008
With the global eradication of smallpox in 1979, the causative agent, variola, no longer circulates in human populations. Other human poxvirus infections, such as those caused by vaccinia, cowpox virus and molluscum, are usually relatively benign in immunocompetent individuals.
Scott Parker, Lauren Handley, R. Mark L. Buller   +2 more
openaire   +3 more sources

Identification of neutralizing nanobodies protecting against poxvirus infection [PDF]

Cell Discovery
An outbreak of mpox has triggered concerns regarding the adequacy of intervention strategies. Passive immunity conferred by neutralizing antibodies exhibits potential in the prophylaxis and treatment of orthopoxvirus infections.
Xuehua Yang, Li Guo, Huarui Duan, Miao Fan, Fengwen Xu, Xiaojing Chi, Shengnan Pan, Xiuying Liu, Xinhui Zhang, Peixiang Gao, Fangyuan Zhang, Xinyi Wang, Fei Guo, Jiwan Ge, Lili Ren, Wei Yang   +15 more
doaj   +2 more sources

Vaccinia Virus Infection in Monkeys, Brazilian Amazon [PDF]

Emerging Infectious Diseases, 2010
To detect orthopoxvirus in the Brazilian Amazon, we conducted a serosurvey of 344 wild animals. Neutralizing antibodies against orthopoxvirus were detected by plaque-reduction neutralizing tests in 84 serum samples.
André T. Silva-Fernandes, Cláudio A. Bonjardim, Cohen, Damaso, de Lopes, de Souza Trindade, Erna G., Felipe L. Assis, Fonseca, Giliane S. Trindade, Iara A. Borges, Jônatas S. Abrahão, Larissa S. Lima, Leite, Lobato, Marcela M.G. Cota, Maria I.M.C. Guedes, Medaglia, Milton F. Souza-Júnior, Paulo C.P. Ferreira, Rafael K. Campos, Ropp, Savona, Silva-Fernandes, Soares-Filho, Zélia I.P. Lobato   +25 more
core   +4 more sources

Orthopoxvirus targets for the development of new antiviral agents [PDF]

Antiviral Research, 2012
Investments in the development of new drugs for orthopoxvirus infections have fostered new avenues of research, provided an improved understanding of orthopoxvirus biology and yielded new therapies that are currently progressing through clinical trials.
Earl R. Kern, Mark N. Prichard
openaire   +4 more sources

Monkeypox Virus and Pregnancy [PDF]

Journal of Medical Virology, Volume 97, Issue 4, April 2025.
ABSTRACT Human monkeypox (Mpox) is a zoonotic disease caused by monkeypox virus (MPXV) present in western Africa and exported sporadically worldwide. MPXV causes illness in individuals and pregnant women which constitute a population at risk with obstetrical and fetal complications including miscarriage, stillbirth and premature delivery.
Jonatane Andrieu, Jean‐louis Mège, Soraya Mezouar   +2 more
wiley   +2 more sources

Serological Evidence of Multiple Zoonotic Viral Infections among Wild Rodents in Barbados [PDF]

Pathogens, 2021
Background: Rodents are reservoirs for several zoonotic pathogens that can cause human infectious diseases, including orthohantaviruses, mammarenaviruses and orthopoxviruses.
Cayol, Claire, Douglas, Kirk Osmond, Forbes, Kristian Michael, Gittens-St. Hilaire, Marquita, Samuels, Thelma Alafia, Sironen, Tarja, Vapalahti, Olli   +6 more
core   +6 more sources

Monkeypox and other orthopoxvirus zoonoses

Veterinary Science Today, 2022
The paper highlights the current knowledge on infection biology, epidemiology and evolution of monkeypox virus (MPXV), cowpox virus (CPXV), buffalopox virus (CPXV), camelpox virus (CMLPV), as well as addresses some factors that modulate dynamics of orthopoxvirus transmission, manifestation of orthopoxvirus infections and their preservation in nature ...
K. Gruzdev
openaire   +3 more sources

Monkeypox: A Mini-Review on the Globally Emerging Orthopoxvirus

International Journal of Environmental Research and Public Health, 2022
Monkeypox is a zoonotic infectious disease belonging to the orthopoxvirus family that has predominantly occurred in West and Central Africa since it was initially discovered in 1958. In May 2022, a global outbreak of monkeypox began to occur on an international scale, with case numbers still rising as this review is being written.
Amy Evans, Bara’ Abdallah AlShurman, Hibah Sehar, Zahid Ahmad Butt   +3 more
openaire   +3 more sources

Domestic Dogs Exposed to Orthopoxvirus in Urban Areas of Brazil. [PDF]

Viruses
de Meneses D, Stoffella-Dutra AG, Blaso VS, de Almeida IM, Dias KL, Domingos IJDS, Ribeiro GP, Coura-Vital W, Reis AB, Vieira TM, Trindade GS.   +10 more
europepmc   +2 more sources

Multivalent vaccine candidate from conserved immunogenic peptides in entry or exit proteins of Orthopoxvirus genus. [PDF]

Sci Rep
de Araújo LP, Silva EN, de Alencar SM, Corsetti PP, de Almeida LA.   +4 more
europepmc   +2 more sources