Results 41 to 50 of about 13,277 (283)

Orthopoxvirus Testing Challenges for Persons in Populations at Low Risk or Without Known Epidemiologic Link to Monkeypox — United States, 2022

MMWR. Morbidity and mortality weekly report, 2022
Since May 2022, approximately 20,000 cases of monkeypox have been identified in the United States, part of a global outbreak occurring in approximately 90 countries and currently affecting primarily gay, bisexual, and other men who have sex with men (MSM)
F. Minhaj, Julia K Petras, Jennifer A. Brown, A. Mangla, Kelly Russo, Christina Willut, Michelle Lee, Jason Beverley, Rachel Harold, Lauren Milroy, B. Pope, E. Gould, Cole Beeler, Jack Schneider, H. Mostafa, Shana Godfred-Cato, E. Click, Brian F Borah, R. Galang, Shama Cash-Goldwasser, Joshua M. Wong, D. McCormick, Patricia A. Yu, Victoria S Shelus, A. Carpenter, Sabrina S. Schatzman, D. Lowe, M. Townsend, W. Davidson, N. Wynn, P. Satheshkumar, S. O'Connor, K. O'Laughlin, A. Rao, A. McCollum, M. Negrón, C. Hutson, J. Salzer, R. Bhatia, Anne A. Kimball, B. Petersen, Yon C. Yu, K. Chatham-Stephens, K. Padgett, Maureen J Miller, I. Zulu, W. Carson, S. Morris, Caroline A. Schrodt, Amy Beeson, D. Kuhar, Z. Chisty   +51 more
semanticscholar   +1 more source

A Game-Theoretic Model of Monkeypox to Assess Vaccination Strategies [PDF]

, 2020
A Game-Theoretic Model of Monkeypox to Assess Vaccination Strategies Sri Vibhaav Bankaru, Depts. of Biomedical Engineering, Math, & Chemistry, Samuel Kossol, William Hou, & Parsa Mahmoudi, with Dr. Jan Rychtar, Dept.
Bankuru, Sri Vibhaav, Hou, William, Kossol, Samuel, Mahmoudi, Parsa, Rychtář, Jan, Taylor, Dewey   +5 more
core   +3 more sources

Skin lesions caused by Orthopoxvirus, cowpox - case report from Poland

Journal of Education, Health and Sport, 2021
Background:Despite the elimination of smallpox, other orthopoxviruses, including cowpox virus, still infect humans. Wild rodents are its natural reservoir.
Konrad Kania, Maria Kalicka, Tomasz Korzec, Przemyslaw Raczkiewicz, Monika Kuc   +4 more
doaj   +1 more source

Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections [PDF]

Viruses, 2010
Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health. The current licensed live vaccinia virus-based smallpox vaccine is extremely effective as a prophylactic vaccine to prevent orthopoxvirus infections, but because of safety issues, it is no ...
Stuart N. Isaacs, Yuhong Xiao
openaire   +4 more sources

Vaccinia Virus Infection in Monkeys, Brazilian Amazon

Emerging Infectious Diseases, 2010
To detect orthopoxvirus in the Brazilian Amazon, we conducted a serosurvey of 344 wild animals. Neutralizing antibodies against orthopoxvirus were detected by plaque-reduction neutralizing tests in 84 serum samples.
Jônatas S. Abrahão, André T. Silva-Fernandes, Larissa S. Lima, Rafael K. Campos, Maria I.M.C. Guedes, Marcela M.G. Cota, Felipe L. Assis, Iara A. Borges, Milton F. Souza-Júnior, Zélia I.P. Lobato, Cláudio A. Bonjardim, Paulo C.P. Ferreira, Giliane S. Trindade, Erna G.   +13 more
doaj   +1 more source

A new attenuated and highly immunogenic orthopoxvirus vaccine protects against mpox in mice and macaques. [PDF]

NPJ Vaccines
Xu F, Huang Y, Hou Y, Xie Y, Huang B, Zhao F, Gao Z, Chen C, Wang J, Mei S, Hu Y, Wang L, Wei L, Zhang J, Li N, Cong Z, Ma J, Zhu L, Chen T, Lu J, Wei Q, Tan W, Xue J, Guo F.   +23 more
europepmc   +2 more sources

Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]

, 2011
Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle, Lieselotte eVande Walle, Mohamed eLamkanfi, Mohamed eLamkanfi   +3 more
core   +2 more sources

Epidemiologic and Ecologic Investigations of Monkeypox, Likouala Department, Republic of the Congo, 2017

Emerging Infectious Diseases, 2019
Monkeypox, caused by a zoonotic orthopoxvirus, is endemic in Central and West Africa. Monkeypox has been sporadically reported in the Republic of the Congo. During March 22–April 5, 2017, we investigated 43 suspected human monkeypox cases. We interviewed
Reena H. Doshi, Sarah Anne J. Guagliardo, Jeffrey B. Doty, Angelie Dzabatou Babeaux, Audrey Matheny, Jillybeth Burgado, Michael B. Townsend, Clint N. Morgan, Panayampalli Subbian Satheshkumar, Nestor Ndakala, Therese Kanjingankolo, Lambert Kitembo, Jean Malekani, Lem’s Kalemba, Elisabeth Pukuta, Tobi N’kaya, Fabien Kangoula, Cynthia Moses, Andrea M. McCollum, Mary G. Reynolds, Jean-Vivien Mombouli, Yoshinori Nakazawa, Brett W. Petersen   +22 more
doaj   +1 more source

Ancient Gene Capture and Recent Gene Loss Shape the Evolution of Orthopoxvirus-Host Interaction Genes

mBio, 2021
Orthopoxviruses (ORPV) include smallpox (variola) virus, one of the most devastating human pathogens, and vaccinia virus, comprising the vaccine used for smallpox eradication.
T. Senkevich, N. Yutin, Y. Wolf, E. Koonin, B. Moss   +4 more
semanticscholar   +1 more source

Viral genomic features predict Orthopoxvirus reservoir hosts

bioRxiv, 2023
Orthopoxviruses (OPVs), including the causative agents of smallpox and mpox have led to devastating outbreaks in human populations worldwide. However, the discontinuation of smallpox vaccination, which also provides cross-protection against related OPVs,
Katie K. Tseng, Heather Koehler, Daniel J. Becker, R. Gibb, Colin J. Carlson, Maria del Pilar Fernandez, Stephanie N. Seifert   +6 more
semanticscholar   +1 more source