Results 51 to 60 of about 11,507 (279)
mBio, 2021 Orthopoxviruses (ORPV) include smallpox (variola) virus, one of the most devastating human pathogens, and vaccinia virus, comprising the vaccine used for smallpox eradication.
T. Senkevich +4 more
semanticscholar +1 more source
Therapeutic Vaccines and Antibodies for Treatment of Orthopoxvirus Infections [PDF]
Viruses, 2010 Despite the eradication of smallpox several decades ago, variola and monkeypox viruses still have the potential to become significant threats to public health. The current licensed live vaccinia virus-based smallpox vaccine is extremely effective as a prophylactic vaccine to prevent orthopoxvirus infections, but because of safety issues, it is no ...
Stuart N. Isaacs, Yuhong Xiao
openaire +4 more sources
Increased susceptibility of Cantagalo virus to the antiviral effect of ST-246® [PDF]
, 2013 Cantagalo virus (CTGV) is the etiologic agent of a pustular disease in dairy cows and dairy workers in Brazil with important economical and occupational impacts. Nevertheless, no antiviral therapy is currently available.
Beltrame, Cristiana O. +8 more
core +1 more source
Development of ST-246® for Treatment of Poxvirus Infections
Viruses, 2010 ST-246 (Tecovirimat) is a small synthetic antiviral compound being developed to treat pathogenic orthopoxvirus infections of humans. The compound was discovered as part of a high throughput screen designed to identify inhibitors of vaccinia virus-induced
Dennis E. Hruby +3 more
doaj +1 more source
Viral genomic features predict Orthopoxvirus reservoir hosts. [PDF]
Commun BiolTseng KK +6 more
europepmc +2 more sources
Inflammasomes: caspase-1-activating platforms with critical roles in host defense [PDF]
, 2011 Activation of the inflammatory cysteine protease caspase-1 in inflammasome complexes plays a critical role in the host response to microbial infections.
Lieselotte eVande Walle +3 more
core +2 more sources
Cowpox after a cat scratch – case report from Poland
Annals of Agricultural and Environmental Medicine, 2015 Cowpox in humans is a rare zoonotic disease; its recognition is therefore problematic due to the lack of clinical experience. The differential diagnosis includes other poxvirus infections and also infections with herpesviruses or selected bacteria.
Karolina Świtaj +3 more
doaj +1 more source
Emerging Infectious Diseases, 2023 Since May 2022, mpox has been identified in 108 countries without endemic disease; most cases have been in gay, bisexual, or other men who have sex with men.
Faisal S. Minhaj +21 more
doaj +1 more source
La variole du dromadaire chez le jeune au Maroc. Isolement et identification du virus. Mise au point du vaccin et application à la prophylaxie [PDF]
, 2000 La variole cameline est une pathologie majeure de l'espèce. Le virus (Orthopoxvirus cameli) a pu être isolé au Maroc. La souche isolée après huit passages sur cellules Vero a été dénommée T8.
El Harrak, Mehdi, Loutfi, C.
core +2 more sources
Genomic Sequencing and Phylogenomics of Cowpox Virus [PDF]
, 2022 Cowpox virus (CPXV; genus Orthopoxvirus; family Poxviridae) is the causative agent of cowpox, a self-limiting zoonotic infection. CPXV is endemic in Eurasia, and human CPXV infections are associated with exposure to infected animals. In the Fennoscandian
Brinkmann, Annika +5 more
core +2 more sources