Results 51 to 60 of about 7,142 (165)

Effect of Monkeypox Virus Preparation on the Lethality of the Intravenous Cynomolgus Macaque Model

Viruses, 2022
For over two decades, researchers have sought to improve smallpox vaccines and also develop therapies to ensure protection against smallpox or smallpox-like disease.
Eric M. Mucker, Josh D. Shamblin, Jo Lynne Raymond, Nancy A. Twenhafel, Robert F. Garry, Lisa E. Hensley   +5 more
doaj   +1 more source

Sero-Epidemiological Survey of Orthopoxvirus in Stray Cats and in Different Domestic, Wild and Exotic Animal Species of Central Italy

Viruses, 2021
Orthpoxvirus infection can spread more easily in a population with a waning immunity with the subsequent emergence/re-emergence of the viruses pertaining to this genus.
Francesca Rosone, Marcello Giovanni Sala, Giusy Cardeti, Pasquale Rombolà, Marina Cittadini, Azzurra Carnio, Roberta Giordani, Maria Teresa Scicluna   +7 more
doaj   +1 more source

Strategic Preparedness of Broad‐Spectrum Antivirals for Rapid Response Towards Next Pandemics

Small Science, Volume 6, Issue 1, January 2026.
Nanoengineered broad‐spectrum antivirals (BSAs) represent a transformative approach to pandemic preparedness. Unlike virus‐specific drugs requiring separate development, BSAs act across multiple viral families through nanoengineering strategies that enhance solubility, bioavailability, and host‐targeted activity.
Sanoj Rejinold N, Geun‐woo Jin, Jin‐Ho Choy   +2 more
wiley   +1 more source

Monkeypox and other orthopoxvirus zoonoses

Veterinary Science Today, 2022
The paper highlights the current knowledge on infection biology, epidemiology and evolution of monkeypox virus (MPXV), cowpox virus (CPXV), buffalopox virus (CPXV), camelpox virus (CMLPV), as well as addresses some factors that modulate dynamics of orthopoxvirus transmission, manifestation of orthopoxvirus infections and their preservation in nature ...
openaire   +2 more sources

Monkeypox Virus in Animals: Current Knowledge of Viral Transmission and Pathogenesis in Wild Animal Reservoirs and Captive Animal Models

Viruses, 2023
Mpox, formerly called monkeypox, is now the most serious orthopoxvirus (OPXV) infection in humans. This zoonotic disease has been gradually re-emerging in humans with an increasing frequency of cases found in endemic areas, as well as an escalating ...
Elizabeth A. Falendysz, Juan G. Lopera, Tonie E. Rocke, Jorge E. Osorio   +3 more
doaj   +1 more source

Research Review on Inhibitors of Lumpy Skin Disease Virus: From Biological Characteristics, Drug Repurposing, to Computer‐Aided Drug Design

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
This review summarizes the research progress on inhibitors of lumpy skin disease virus (LSDV), focusing on its biological characteristics and key proteins involved in the viral replication cycle. It compiles various inhibitors (direct‐acting poxvirus inhibitors and host‐directed poxvirus inhibitors) against poxviruses, their mechanisms of action, and ...
Leilei ZHAO, Jing QU, Miao AN, Yang LIU, Xiubo LI, Yiming LIU, Chen PENG, Todd R. Callaway   +7 more
wiley   +1 more source

Whole genome sequencing of recombinant viruses obtained from co-infection and superinfection of Vero cells with modified vaccinia virus ankara vectored influenza vaccine and a naturally occurring cowpox virus

Frontiers in Immunology
Modified vaccinia virus Ankara (MVA) has been widely tested in clinical trials as recombinant vector vaccine against infectious diseases and cancers in humans and animals.
Diana Diaz-Cánova, Ugo Moens, Annika Brinkmann, Andreas Nitsche, Malachy Ifeanyi Okeke   +4 more
doaj   +1 more source

Serologic evidence of human orthopoxvirus infections in Sierra Leone

BMC Research Notes, 2011
Background Orthopoxviruses, including variola virus, vaccinia virus, and monkeypox virus, have previously been documented in humans in West Africa, however, no cases of human orthopoxvirus infection have been reported in the region since 1986.
Goba Augustine, Lungay Victor K, Robert Willie, Kanneh Lansana D, Fonnie Richard, Lash RR, Reynolds Mary G, Abel Jason, MacNeil Adam, Moses Lina M, Damon Inger K, Karem Kevin, Bausch Daniel G   +12 more
doaj   +1 more source

Operationalizing a Hub‐and‐Spoke Telemedicine Model for Mpox Surveillance in a High‐Alert, Zero‐Prevalence Setting: An Observational Study, Real‐World Experience From Iran

Interdisciplinary Perspectives on Infectious Diseases, Volume 2026, Issue 1, 2026.
Background The global monkeypox (Mpox) outbreak prompted heightened surveillance in regions with significant travel links. Fars Province, Iran, implemented a structured telemedicine response to manage patients presenting with Mpox‐like symptoms. Objectives This study aimed to describe and evaluate the impact of a tiered, hub‐and‐spoke telemedicine ...
Owrang Eilami, Nader Eilami, Alireza Heiran, Mehdi Nejat, Mehrab Sayadi, Suraiya Saleem   +5 more
wiley   +1 more source

The Impact of Monkeypox Virus Infection on Pregnancy Outcome: Clinical Features and Potential Pathogenic Mechanisms

Journal of Immunology Research, Volume 2026, Issue 1, 2026.
Monkeypox has garnered significant attention following its emergence in multiple countries and its designation as a global health emergency in 2022. There is a notable deficiency in clinical and experimental data regarding pregnancy outcomes following monkeypox infection.
Jingyi Wu, Fangbin Huang, Qingliang Zheng, Poorani Gurumallesh   +3 more
wiley   +1 more source