Results 61 to 70 of about 11,628 (248)

Changes in HIV‐1 Reservoir Dynamics After Mpox Infection

Journal of Medical Virology, Volume 97, Issue 11, November 2025.
ABSTRACT In May 2022, a large outbreak of monkeypox virus (MPXV) occurred in several non‐endemic regions worldwide. Another outbreak in 2024 raised global concerns, particularly for immunocompromised individuals like people with HIV (PWH). Since the latent HIV‐1 reservoir remains a major barrier to a cure, we investigated how past mpox infection ...
Guiomar Casado‐Fernández, Olivia de la Calle‐Jiménez, Inés Armenteros, Luis Lemus Aguilar, Daniel Fuertes, Juan Cantón, Elena Mateos, Noemi Cabello, Javier Rodríguez Añover, Anabel Negredo, Miguel Cervero, María Paz Sánchez Seco, Montserrat Torres, Vicente Estrada, Mayte Coiras   +14 more
wiley   +1 more source

Seasonality of human orthopoxvirus infections

, 2022
Variola infections (smallpox) showed seasonality in temperate climates. This sharp seasonality (peaking in the Winter-Spring) may have important ramifications for control and elimination of human monkeypox (MPX) and should be considered in planning public health response.
Andrew Lover, Andrew Noymer
openaire   +1 more source

Structural conservation and functional diversity of the Poxvirus Immune Evasion (PIE) domain superfamily [PDF]

, 2015
Poxviruses encode a broad array of proteins that serve to undermine host immune defenses. Structural analysis of four of these seemingly unrelated proteins revealed the recurrent use of a conserved beta-sandwich fold that has not been observed in any ...
Alcami, Alejo, Altekar, Altschul, Baker, Buatois, Bursill, Byun, Christopher Nelson, Clark, Dabbagh, Daved Fremont, Deane, Finn, Graham, Hendrickson, Hnatiuk, Jabari Elliott, Kelley, Kelley, Lalani, Lateef, Lateef, Lee, Lin, Loparev, McCoy, Megan Epperson, Ng, Pelham, Reading, Rozwarski, Ruiz-Arguello, Seet, Silverman, Smith, Sukrit Singh, Upton, Werden, White, Wilkins   +40 more
core   +3 more sources

Pixelated pathologies: Camera trapping as a tool for monitoring wildlife health

Journal of Applied Ecology, Volume 62, Issue 11, Page 2894-2913, November 2025.
Given the increasing emergence of diseases, some with conservation and public health implications, improving and expanding wildlife health surveillance strategies is imperative. Camera trapping is particularly relevant for detecting new outbreaks, monitoring high‐risk zones and evaluating risk mitigation measures. Abstract Camera trapping has become an
Patricia Barroso, Pablo Palencia
wiley   +1 more source

Genesis of Monkeypox

Journal of Pure and Applied Microbiology, 2022
A zoonotic orthopoxvirus known as monkeypox inadvertently produces a smallpox-like illness in humans but with far fewer fatalities. This infection is indigenous to most parts of the African continent, with outbreaks throughout the Western World linked to
Abdul Basit, Jasni Mohamad Zain, Hafiza Zoya Mojahid, Mushtaq Ali   +3 more
doaj   +1 more source

Primary Human Macrophages Serve as Vehicles for Vaccinia Virus Replication and Dissemination [PDF]

, 2014
Human monocytic and professional antigen-presenting cells have been reported only to exhibit abortive infections with vaccinia virus (VACV). We found that monocyte-derived macrophages (MDMs), including granulocyte macrophage colony-stimulating factor (GM-
Amet, Tohti, Byrd, Daniel, Desai, Mona, Hu, Ningjie, Lan, Jie, Shepherd, Nicole, Yang, Kai, Yu, Qigui   +7 more
core   +1 more source

Organoid Models to Study Human Infectious Diseases

Cell Proliferation, Volume 58, Issue 11, November 2025.
Our manuscript reviews the role of organoids as models for studying human infectious diseases, highlighting their irreplaceable contributions to drug testing and vaccine development for significant infectious diseases including HIV, ZIKV, SARS‐CoV‐2 and MPXV.
Sijing Zhu, Dan Chen, Xinzhi Yang, Liuliu Yang, Yuling Han   +4 more
wiley   +1 more source

Smallpox, Monkeypox and Other Human Orthopoxvirus Infections

Viruses, 2022
Considering that vaccination against smallpox with live vaccinia virus led to serious adverse effects in some cases, the WHO, after declaration of the global eradication of smallpox in 1980, strongly recommended to discontinue the vaccination in all countries.
Galina A. Shchelkunova, Sergei N. Shchelkunov   +1 more
openaire   +3 more sources

Potential Risk of Local Transmission of Mpox in Nepal: An Emerging Public Health Concern

Health Science Reports, Volume 8, Issue 9, September 2025.
ABSTRACT Background and Aims Monkeypox (Mpox) is a zoonotic disease caused by the monkeypox virus, a double‐stranded DNA virus of the Orthopoxvirus genus with two major clades (Clades I and II), with Clade IIb responsible for most global cases reported during 2022–2024.
Yogendra Shah, Ankit Kumar Singh, Bipin Kumar Acharya, Mandira Lamichhane, Ram Singh Dhami, Kishor Pandey, Shyam Prakash Dumre, Kouichi Morita, Basu Dev Pandey, Meghnath Dhimal   +9 more
wiley   +1 more source

Ophthalmic Features and Implications of Poxviruses: Lessons from Clinical and Basic Research

Microorganisms, 2022
Amidst the ongoing monkeypox outbreak, global awareness has been directed towards the prevention of viral transmission and case management, with the World Health Organization declaring the outbreak a public health emergency of international concern ...
Tolulope Fashina, Ye Huang, Joanne Thomas, Christopher D. Conrady, Steven Yeh   +4 more
doaj   +1 more source