Results 161 to 170 of about 2,452 (215)

Potential of rosmarinic acid from Orthosiphon aristatus extract for inflammatory induced diseases and its mechanisms of action.

Life Science, 2023
Orthosiphon aristatus has been traditionally used as a medicinal herb for various illnesses in Southeast Asia and Europe. The most dominant bioactive compound of the herb is rosmarinic acid (RosA) which has been demonstrated for its remarkable anti ...
S. E. Saberi, Lee Suan Chua
semanticscholar   +1 more source

Novel cytotoxic constituents of Orthosiphon diffusus

Tetrahedron Letters, 2011
Abstract Chemical investigation on Orthosiphon diffusus resulted in the isolation of four relatively rare, novel polychiral furanopyrans, orthodiffenes A–D (1–4) which were characterized from detailed studies of their 1D and 2D NMR spectra. The X-ray crystallographic analysis of orthodiffene A (1) was accomplished.
Holla, Harish, Srinivas, Yallamalla, Majhi, Anjoy, Srinivasulu, Gannoju, Sridhar, Balasubramanian, Krishna, Arepalli Sai, Rao, Janapala Venkateswara, Das, Biswanath   +7 more
openaire   +2 more sources

Molecular Modeling and Simulation of Transketolase from Orthosiphon stamineus

Current Computer-Aided Drug Design, 2019
Background: Orthosiphon stamineus is a traditional medicinal plant in Southeast Asia countries with various well-known pharmacological activities such as antidiabetic, diuretics and antitumor activities. Transketolase is one of the proteins identified in the leaves of the plant and transketolase is believed able to lower blood sugar level in human ...
Ng, Mei Ling, Rahmat, Zaidah, Omar, Mohd. Shahir Shamsir   +2 more
openaire   +3 more sources

Diuretic Action of AqueousOrthosiphonExtract in Rats

Planta Medica, 1992
An aqueous extract of Orthosiphonis folium, given orally, enhances considerably ion excretion in rat to a level comparable to that obtained with furosemide. No aqueretic action is observed. The increased ion excretion is not due to the potassium content of the starting material.
J, Englert, G, Harnischfeger
openaire   +2 more sources

Biswulfenioidins A–E, dioxygen-bridged abietane-type diterpenoid dimers with anti-Zika virus potential from Orthosiphon wulfenioides

Organic Chemistry Frontiers
Six dioxygen-bridged abietane-type diterpenoid dimers with unprecedented angular fused and rare parallel fused structures were isolated from Orthosiphon wulfenioides.
Wen‐Chao Tu, Yong-Xiang Huang, Yuan-Lin Kong, Bo Li, Bin-Bao Wang, Tian-Hao Dong, Wei-chi Chen, Muhammad Aurang Zeb, Xiao-Li Li, Mei-Feng Liu, Chang-Bo Zheng, Weilie Xiao   +11 more
semanticscholar   +1 more source

Dual Phytochemical/Activity-Guided Optimal Preparation and Bioactive Material Basis of Orthosiphon Stamineus Benth. (Shen Tea) against Nonalcoholic Fatty Liver Disease.

Journal of Agricultural and Food Chemistry
Orthosiphon stamineus Benth. (OSB) is a popular plant used for making "Shen tea" or "Java tea". It has been demonstrated with antioxidant, anti-inflammatory, and hepatoprotective activities.
Zheng Li, Qiongyue Cao, Hao Chen, Junyi Yang, Zhihao Wang, Xiangquan Qu, Yuqin Yao, Zhengkun Zhou, Wei Zhang   +8 more
semanticscholar   +1 more source

Four Highly Oxygenated Isopimarane-Type Diterpenes of Orthosiphon stamineus

Planta Medica, 2002
Four highly oxygenated isopimarane-type diterpenes, named orthosiphols O, P and Q and nororthosiphonolide A, have been isolated from the aerial parts of Orthosiphon stamineus from Myanmar, together with three known diterpenes, orthosiphols D and E and orthosiphonone A. Their structures were determined on the basis of extensive spectral analysis.
Awale, Suresh, Tezuka, Yasuhiro, Banskota, Arjun H., Kouda, Kyoji, Tun, Kyaw Myint, Kadota, Shigetoshi   +5 more
openaire   +3 more sources

Staminol A, a novel diterpene from Orthosiphon stamineus

Tetrahedron Letters, 1999
Abstract From the aerial part of a Vietnamese medicinal plant, Orthosiphon stamineus Benth . (Lamiaceae), staminol A (1), a diterpene with a novel carbon framework, was isolated together with four new isopimarane-type diterpenes, orthosiphols FI (2–5). Their structures were elucidated by the spectroscopic analyses.
Stampoulis, Pavlos, Tezuka, Yasuhiro, Banskota, Arjun H., Tran, Kim Qui, Saiki, Ikuo, Kadola, Shigetoshi   +5 more
openaire   +2 more sources

Bioactivity-guided isolation of potent inflammasome and mitochondria damage inhibitory diterpenoids from Orthosiphon wulfenioides.

Phytochemistry
Orthosiphon wulfenioides is a medicinal plant to treat arthritis, vascular inflammation, edema, and dyspepsia. To explore the anti-inflammatory components and their mechanism of action, 12 previously undescribed highly oxidized diterpenes, wulfenioidones
Wen‐Chao Tu, Peng-Yun Yang, Xing-Jie Zhang, Yuan-Lin Kong, Bo Li, Hui-Juan Wang, Muhammad Aurang Zeb, Xiao-Li Li, Mei-Feng Liu, Weilie Xiao   +9 more
semanticscholar   +1 more source

APPLICATION OF ORTHOSIPHON STAMINEUS FOR DIURETIC EFFECT

2017
Journal of Medicine and Health Sciences, 24 ...
openaire   +1 more source