Results 91 to 100 of about 1,477,564 (205)
Neurobiology of Disease, 2020 L-DOPA-induced dyskinesia (LID) is a major complication of long-term dopamine replacement therapy in Parkinson's disease. Characteristic neural oscillation and abnormal activity of striatal projection neurons (SPNs) are typical pathological events of LID,
Cong Zheng +10 more
doaj
Proceedings of the National Academy of Sciences of the United States of America, 2006 Notch signaling components such as the basic helix-loop-helix gene Hes1 are cyclically expressed by negative feedback in the presomitic mesoderm (PSM) and constitute the somite segmentation clock.
Yoshito Masamizu +7 more
semanticscholar +1 more source
Free Energy of ATP hydrolysis manipulates the cellular calcium signals [PDF]
arXiv, 2018 In living cells, oscillation of the concentration of cytosolic Ca2+ is an important and pervasive signal for the intercellular and intracellular information conduction. To generate the oscillation, the hydrolysis of ATP is always needed. Many recent studies show that both ATP molecules themselves and the free energy by ATP hydrolysis play significant ...
arxiv
Anesthesia and Analgesia, 2004 Accumulating evidence suggests that reduction of intrinsic excitability or synaptic excitation and/or an enhancement of synaptic inhibition underlie the general anesthetic condition.
E. Masaki, M. Kawamura, F. Kato
semanticscholar +1 more source
Signal transduction by the platelet integrin alpha IIb beta 3: induction of calcium oscillations required for protein-tyrosine phosphorylation and ligand-induced spreading of stably transfected cells. [PDF]
, 1992 Anthony J. Pelletier +2 more
openalex +1 more source
Plant Physiology, 2015 Rapid closure of stomata occurs at an optimum frequency in Ca2+ and voltage oscillations, but this optimum emerges in simulations as a by-product of the transport that drives closure rather than as a signal that regulates it.
Carla Minguet-Parramona +8 more
semanticscholar +1 more source
ATP-Independent Luminal Oscillations and Release of Ca2+ and H+ from Mast Cell Secretory Granules: Implications for Signal Transduction [PDF]
, 2003 Iván Quesada +2 more
openalex +1 more source
Linear noise approximation of noise-induced oscillation in NF-κB signaling network [PDF]
arXiv, 2010 NF-{\kappa}B, one of key regulators of inflammation, apoptosis, and differentiation, was found to have noisy oscillatory shuttling between the nucleus and the cytoplasm in single cells when cells are stimulated by cytokine TNF{\alpha}. We present the analytical analysis which uncovers the underlying physical mechanisms of this spectacular noise-induced
arxiv
From Intracellular Signaling to Population Oscillations: Bridging Scales in Collective Behavior [PDF]
arXiv, 2014 Collective behavior in cellular populations is coordinated by biochemical signaling networks within individual cells. Connecting the dynamics of these intracellular networks to the population phenomena they control poses a considerable challenge because of network complexity and our limited knowledge of kinetic parameters.
arxiv
A p53 Oscillator Model of DNA Break Repair Control [PDF]
arXiv, 2005 The transcription factor p53 is an important regulator of cell fate. Mutations in p53 gene are associated with many cancers. In response to signals such as DNA damage, p53 controls the transcription of a series of genes that cause cell cycle arrest during which DNA damage is repaired, or triggers programmed cell death that eliminates possibly cancerous
arxiv