Results 91 to 100 of about 50,029 (292)

Rapid and sustained nuclear–cytoplasmic ERK oscillations induced by epidermal growth factor

open access: yesMolecular Systems Biology, 2009
Although the ERK pathway has a central role in the response of cells to growth factors, its regulatory structure and dynamics are incompletely understood. To investigate ERK activation in real time, we expressed an ERK–GFP fusion protein in human mammary
Harish Shankaran   +6 more
doaj   +1 more source

Pluripotency, differentiation, and reprogramming: A gene expression dynamics model with epigenetic feedback regulation

open access: yes, 2015
Characterization of pluripotent states, in which cells can both self-renew and differentiate, and the irreversible loss of pluripotency are important research areas in developmental biology. In particular, an understanding of these processes is essential
Furusawa, Chikara   +2 more
core   +3 more sources

5,11‐Di(thiophen‐2‐yl)Tetracene: A Novel Tetracene Derivative for Efficient Singlet Fission with Enhanced Physical and Chemical Stability in Thin Films

open access: yesAdvanced Functional Materials, EarlyView.
In this work, a new tetracene derivative, 5,11‐di(thiophen‐2‐yl)tetracene (2T‐Tc) is introduced, exhibiting enhanced physical and chemical stability, and retaining favorable singlet fission kinetics with near unity triplet pair yield in thin films.
Jieun Lee   +11 more
wiley   +1 more source

The circadian clock protein Cryptochrome 1 is a direct target and feedback regulator of the Hippo pathway

open access: yesiScience, 2023
Summary: Circadian clock controls daily behavior and physiology. The activity of various signaling pathways affects clock gene expression. Here, we show that the core circadian clock gene CRY1 is a direct target of the Hippo pathway effector YAP.
Abdelhalim Azzi   +5 more
doaj  

Phase responses of oscillating components in a signaling pathway

open access: yesFrontiers in Physiology, 2013
Signal transduction pathways control various events in mammalian cells such as growth, proliferation,differentiation, apoptosis, or migration in response to environmental stimuli.Because of their importance, the activity of signaling pathways is ...
Masaki eNomura, Mariko eOkada-Hatakeyama
doaj   +1 more source

Carbon Nanotube 3D Integrated Circuits: From Design to Applications

open access: yesAdvanced Functional Materials, EarlyView.
As Moore's law approaches its physical limits, carbon nanotube (CNT) 3D integrated circuits (ICs) emerge as a promising alternative due to the miniaturization, high mobility, and low power consumption. CNT 3D ICs in optoelectronics, memory, and monolithic ICs are reviewed while addressing challenges in fabrication, design, and integration.
Han‐Yang Liu   +3 more
wiley   +1 more source

A nested bistable module within a negative feedback loop ensures different types of oscillations in signaling systems

open access: yesScientific Reports, 2023
In this article, we consider a double phosphorylation cycle, a ubiquitous signaling component, having the ability to display bistability, a behavior strongly related to the existence of positive feedback loops.
Juan Ignacio Marrone   +2 more
doaj   +1 more source

Multi‐Pathway Upconversion Emission in Symmetry‐Broken Nanocavities: Broadband Multiresonant Enhancement and Anti‐Correlated Interfacial Sensitivity

open access: yesAdvanced Functional Materials, EarlyView.
Symmetry‐broken plasmonic nanoantenna arrays achieve broadband multiresonant enhancement of second harmonic generation (SHG), third harmonic generation (THG), and upconversion photoluminescence (UCPL), under femtosecond laser excitation across the near‐infrared range (1000–1600 nm).
Elieser Mejia   +9 more
wiley   +1 more source

A Novel Approach to Implementing Artificial Thalamic Neurons with Ferroelectric Transistors

open access: yesAdvanced Functional Materials, EarlyView.
Artificial neurons created using CMOS technology often require a large number of transistors and capacitors. This study introduces an artificial thalamic neuron that employs only five CMOS compatible ferroelectric transistors. The manufactured thalamic neuron demonstrates leaky integrate‐and‐fire‐or‐burst (LIFB) functionalities, featuring self ...
Andreas Grenmyr   +7 more
wiley   +1 more source

In vivo characterization of hippocampal electrophysiological processes in the heterozygous Pten knockout model of autism [PDF]

open access: yes, 2018
While cognitive deficits have been described in the heterozygous Pten (+/-) KO mouse model of autism, little work has been done to demonstrate how corresponding in vitro physiological alterations in this model may underpin these cognitive deficits in ...
Barry, Jeremy   +2 more
core   +1 more source

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