Results 81 to 90 of about 50,029 (292)

A case report of a family with developmental arrest of human prokaryotic stage zygote

open access: yesFrontiers in Cell and Developmental Biology
To study the genetic variation leading to the arrest phenotype of pronuclear (PN) zygotes. We recruited a family characterized by recurrent PN arrest during in vitro fertilization (IVF) and intracytoplasmic sperm injection cycles (ICSI) and performed ...
Tianzhong Ma   +5 more
doaj   +1 more source

Receptor-specific Ca2+ oscillation patterns mediated by differential regulation of P2Y purinergic receptors in rat hepatocytes

open access: yesiScience, 2021
Summary: Extracellular agonists linked to inositol-1,4,5-trisphosphate (IP3) formation elicit cytosolic Ca2+ oscillations in many cell types, but despite a common signaling pathway, distinct agonist-specific Ca2+ spike patterns are observed.
Juliana C. Corrêa-Velloso   +5 more
doaj  

An oscillating reaction network with an exact closed form solution in the time domain

open access: yesBMC Bioinformatics, 2023
Background Oscillatory behavior is critical to many life sustaining processes such as cell cycles, circadian rhythms, and notch signaling. Important biological functions depend on the characteristics of these oscillations (hereafter, oscillation ...
Joseph Hellerstein
doaj   +1 more source

Oscillating on Borrowed Time: Diffusible Signals from Immortalized Suprachiasmatic Nucleus Cells Regulate Circadian Rhythmicity in Cultured Fibroblasts [PDF]

open access: yesThe Journal of Neuroscience, 2001
The capacity to generate circadian rhythms endogenously and to confer this rhythmicity to other cells was compared in immortalized cells derived from the suprachiasmatic nucleus (SCN) and a fibroblast line to differentiate SCN pacemaker properties from the oscillatory behavior of non-clock tissues.
Jodie Rappe   +3 more
openaire   +3 more sources

Print‐and‐Plate Architected Electrodes for Electrochemical Transformations Under Flow

open access: yesAdvanced Functional Materials, EarlyView.
Typical flow cell electrodes are composed of stochastic porous carbon, limiting understanding of electrode structure‐performance relationships. This work describes an approach, termed “print‐and‐plate,” to prepare porous electrodes by direct ink writing followed by conformal metal coating.
Dylan M. Barber   +12 more
wiley   +1 more source

Oscillatory calcium release and sustained store-operated oscillatory calcium signaling prevents differentiation of human oligodendrocyte progenitor cells

open access: yesScientific Reports, 2022
Endogenous remyelination in demyelinating diseases such as multiple sclerosis is contingent upon the successful differentiation of oligodendrocyte progenitor cells (OPCs).
Richard A. Seidman   +4 more
doaj   +1 more source

Toward Architected Microstructures Using Advanced Laser Beam Shaping in Laser Powder Bed Fusion of Ti‐6Al‐4V

open access: yesAdvanced Functional Materials, EarlyView.
This research applies advanced laser beam shaping (LCoS‐SLM) to fabricate the Ti‐6Al‐4V alloy via laser powder bed fusion. A tailored beam is used to prevent martensite formation and create a dual α+β microstructure by controlling cooling rates.
Reza Esmaeilzadeh   +8 more
wiley   +1 more source

Stochasticity of intranuclear biochemical reaction processes controls the final decision of cell fate associated with DNA damage. [PDF]

open access: yesPLoS ONE, 2014
A massive integrative mathematical model of DNA double-strand break (DSB) generation, DSB repair system, p53 signaling network, and apoptosis induction pathway was constructed to explore the dominant factors of unknown criteria of cell fate decision.
Kazunari Iwamoto   +3 more
doaj   +1 more source

Bioorthogonal Engineering of Cellular Microenvironments Using Isonitrile Ligations

open access: yesAdvanced Functional Materials, EarlyView.
Highly selective chemistries are required for fabrication and post‐cross–linking modification of cell‐encapsulating hydrogels used in tissue engineering applications. Isonitrile ligation reactions represent a promising class of bioorthogonal chemistries for engineering hydrogel‐based cellular microenvironments. Isonitrile‐based hydrogels are stable and
Ping Zhou   +2 more
wiley   +1 more source

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