Results 111 to 120 of about 115,464 (311)
Advanced Science, EarlyView.A periosteum‐inspired Janus piezoelectric scaffold converts micromechanical forces into electrical signals and synergizes with controlled resveratrol release. This dual action reprograms endothelial metabolism, drives H‑type vessel formation, and restores bone–vessel coupling in diabetic bone defects.
Kai Wang, Kai Jiang
wiley +1 more source
Cell therapy in bone healing disorders
Orthopedic Reviews, 2010 In addition to osteosynthetic stabilizing techniques and autologous bone transplantations, so-called orthobiologics play an increasing role in the treatment of bone healing disorders.
Marcus Jäger +6 more
doaj +1 more source
FOS3D: A Fluorescence‐Enabled Toolkit for Characterizing a Three‐dimensional Osteosarcoma Model
Advanced Science, EarlyView.FOS3D describes fluorescent (F) osteosarcoma (OS) cells in a tri‐dimensional (3D) model. The study comprises three phases: development, where biofabrication parameters are tuned to achieve cytocompatibility and tumor‐specific mechanical properties in cell‐laden gelatin methacryloyl constructs; validation, where whole‐well fluorescence reading is ...
William Humble +9 more
wiley +1 more source
Enhancement of osteoblast activity on nanostructured NiTi/hydroxyapatite coatings on additive manufactured NiTi metal implants by nanosecond pulsed laser sintering [PDF]
, 2018 Biwei Deng,1,2 Angela Bruzzaniti,3 Gary J Cheng1,2 1School of Industrial Engineering, Purdue University, West Lafayette, IN 47907, USA; 2Birck Nanotechnology Center, Purdue University, West Lafayette, IN 47907, USA; 3Department of Biomedical and Applied
Deng B, Cheng GJ, Bruzzaniti A
core
Promoting implant osseointegration via the osteoblast-selective β-amino acid polymer strategy
Nature CommunicationsOsseointegration for implants, especially bioinert implants, poses significant clinical challenges. Overcoming fibrotic encapsulation and promoting osseointegration at the implant interface are critical for successful bone repair, which highly expected ...
Qi Chen +10 more
doaj +1 more source
Advanced Science, EarlyView.This study utilized alloy micro‐galvanic coupling design to regulate the release of essential elements, thereby programming immune responses and promoting regeneration. The sacrificial anodic process of Zn‐0.8Mg reduced Zn2+ release compared to the “large cathode‐small anode” coupling of Zn‐0.8Fe.
Chaoyang Sun +14 more
wiley +1 more source
On a Class of Bone Cell-Based Remodeling Laws with Spatial Fading Influence of Stimuli
Engineering Transactions, 2015 In the present paper the class of cell-based bone remodeling laws is considered. The fundamental assumption is that of fading in space influence on actor cells osteocytes functioning as sensors.
T. Lekszycki
doaj +1 more source
Advanced Science, EarlyView.Both SVF and CD31+ SVF improve spontaneous osteoarthritis, but CD31+ enrichment refines the therapeutic profile rather than broadly enhancing all effects. More distinct benefits are observed in extracellular matrix remodeling, osteochondral integrity, and subchondral/trabecular bone preservation, supporting CD31+‐enriched SVF as a biologically enhanced
Sijia Zhou +16 more
wiley +1 more source
Effects of simvastatin-loaded polymeric micelles on human osteoblast-like MG-63 cells [PDF]
, 2012 To develop an optimized simvastatin (SV) delivery device for bone regeneration, SV-loaded poly(ethylene glycol)-poly(ɛ-caprolactone) (PECL) micelles were constructed. The micelles had an average size of 80 nm.
Shaobing Li +10 more
core
Induction of osteoblast apoptosis stimulates macrophage efferocytosis and paradoxical bone formation
Bone ResearchApoptosis is crucial for tissue homeostasis and organ development. In bone, apoptosis is recognized to be a main fate of osteoblasts, yet the relevance of this process remains underexplored.
Lena Batoon +11 more
doaj +1 more source