Results 111 to 120 of about 38,017 (252)

Unveiling the potential of Butylphthalide: inhibiting osteoclastogenesis and preventing bone loss

Frontiers in Pharmacology
Osteoporosis, resulting from overactive osteoclasts and leading to elevated fracture risk, has emerged as a global public health concern due to the aging population.
Feng Yanbin, Feng Yanbin, Teng Yilin, Mo Yaomin, Xi Deshuang, Zhou Junhong, Zeng Gaofeng, Zong Shaohui, Zong Shaohui   +8 more
doaj   +1 more source

Nanostructured magnesium has fewer detrimental effects on osteoblast function

, 2013
Lucy Weng, Thomas J Webster School of Engineering and Department of Orthopedics, Brown University, Providence, RI, USA Abstract: Efforts have been made recently to implement nanoscale surface features on magnesium, a biodegradable metal, to increase bone
Weng L, Webster TJ
core  

Osteoblast - 2

, 2010
An image from a bone marrow showing an osteoblast (labeled)
Fraser, Marion
core   +1 more source

The Adipose‐Sympathetic Nerve Crosstalk: FSTL1 as an Adipocyte‐Derived Neurotrophic Factor for WAT Browning

Advanced Science, EarlyView.
As a novel adipose‐derived neurotrophic factor, Follistatin‐like 1 is endocytosed by sympathetic neurons primarily via tropomyosin‐related kinase B. This process promotes sympathetic innervation in adipose tissue and norepinephrine release, leading to white adipose tissue browning, enhanced thermogenesis, and anti‐obesity effects in mice.
Xiao‐Wei Jia, Jia‐Xin Liu, Rui‐Ping Wang, Xue‐Qin Wu, Yao Che, Mu‐Chen Wu, Hong‐Wei Shang, Xin Lu, Tao Lu, Lu‐Lu Wang, Chun‐Yan Jiang, Dong‐Liang Fang, Chun Yang, Yan Gao   +13 more
wiley   +1 more source

Role of oxytocin in bone

Frontiers in Endocrinology
Oxytocin (OT) is a posterior pituitary hormone that, in addition to its role in regulating childbirth and lactation, also exerts direct regulatory effects on the skeleton through peripheral OT and oxytocin receptor (OTR).
Tianming Wang, Jianya Ye, Jianya Ye, Yongqiang Zhang, Jiayi Li, Tianxiao Yang, Yufeng Wang, Xiao Jiang, Qingqiang Yao   +8 more
doaj   +1 more source

Nanocoating with plant-derived pectins activates osteoblast response in vitro

, 2016
J Folkert,1 A Meresta,1 T Gaber,2 K Miksch,1 F Buttgereit,2 J Detert,2 N Pischon,3,* K Gurzawska3,4,* 1Environmental Biotechnology Department, Faculty of Power and Environmental, Silesian University of Technology, Gliwice, Poland; 2Department of ...
Meresta A, Detert J, Gurzawska K, Pischon N, Miksch K, Buttgereit F, Folkert J, Gaber T   +7 more
core  

Osteoblast - 1

, 2014
An image from a bone marrow showing an osteoblast (labeled)
Fraser, Marion
core   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Potential threats of environmental microplastics to the skeletal system: current insights and future directions

Frontiers in Endocrinology
Micro- and nanoplastics (MNPs), as emerging environmental pollutants, have attracted global attention due to their pervasive presence in ecosystems and human living environments.
Haofan Zhao, Sirong Mu, Weizhou Wang, Xi Li   +3 more
doaj   +1 more source

Osteoblast - 3

, 2010
An image from a bone marrow showing an osteoblast (labeled)
Fraser, Marion
core   +1 more source