Results 101 to 110 of about 115,464 (311)

Osteoblasts subjected to tensile force induce osteoclastic differentiation of murine macrophages in a coculture system

open access: yesJournal of Dental Sciences, 2015
Background/purpose: Bone remodeling is regulated by the replacement of old bone with new bone through sequential osteoclastic resorption and osteoblastic bone formation.
Yi-Jyun Chen   +5 more
doaj   +1 more source

BCMA‐Engineered Dendritic Cell‐Derived Exosomes as Bi‐Functional Therapeutics Orchestrating Cytokine Sequestration and Immune Activation for Multiple Myeloma

open access: yesAdvanced Science, EarlyView.
A dual‐function cell‐free therapeutic based on DC2.4 cell‐derived exosomes engineered to display BCMA. (Left) Soluble Ligand Sequestration (Decoy Function): DB Exo act as molecular decoys that predominantly sequester soluble APRIL with partial BAFF attenuation, effectively disrupting the NF‐κB survival signaling axis and suppressing myeloma cell ...
Yuqing Zeng   +5 more
wiley   +1 more source

Cytokine Release from Osteoblasts in Response to Ultrasound Stimulation [PDF]

open access: yes, 2009
Bone is a dynamic tissue with a well-balanced homeostasis preserved by both formation and resorption of bone. Normal turnover of bone, however, can be upset by either increased osteoclast activity or decreased osteoblast function; either mechanism alone ...
Li, J.K.; Chang, W.H.; Lin, J.C.; Ruaan, R.C.; Liu, H.C.; Sun, J.S.   +1 more
core  

Type I diabetic osteoporosis and osteoblast apoptosis [PDF]

open access: yes, 2012
TYPE I DIABETIC OSTEOPOROSIS AND OSTEOBLAST APOPTOSIS ByLindsay Martin CoeType I diabetes is a metabolic disorder that affects roughly 1 million people in the United States.
Coe, Lindsay Martin
core   +1 more source

The Enkephalinergic Osteoblast [PDF]

open access: yesJournal of Bone and Mineral Research, 1998
H, Rosen, A, Krichevsky, Z, Bar-Shavit
openaire   +2 more sources

Osteoblasts and The Hematopoietic Microenvironment

open access: yesHematology, 1999
Cells of the bone marrow are chiefly dedicated to two processes; the production of blood, and the production of bone that houses the hematopoietic organ. The majority of our understanding of these processes comes from data focused on one of these functions. Yet, in vivo the processes are intermixed.
R S, Taichman, M J, Reilly, S G, Emerson
openaire   +2 more sources

Oxygen Vacancy‐Enriched Platinum Single‐Atom Nanozyme Wrapped in Nanoislands: Unlocking Catalytic Activity and Reprogramming Redox Microenvironment for Osteonecrosis Repair

open access: yesAdvanced Science, EarlyView.
CeO2‐x/Pt single‐atom nano‐island is constructed via low‐temperature reduction, featuring abundant oxygen vacancies and an island–sea structure. It delivers outstanding multi‐enzyme‐mimetic activity and ROS‐scavenging efficiency. Density functional theory reveals optimized electronic structures and reaction pathways.
Yang Zhu   +12 more
wiley   +1 more source

Engineered Exosomal miR‐146a‐5p Reprograms BMSC Fate and Restores Mitochondrial Homeostasis in Glucocorticoid‐Induced Osteonecrosis of Femoral Head

open access: yesAdvanced Science, EarlyView.
Exosomal miR‐146a‐5p is identified as a pivotal regulator in steroid‐induced osteonecrosis. Its reduction activates NF‐κB signaling, compromises mitophagy, and disrupts mitochondrial bioenergetics, resulting in autophagic disequilibrium. Engineered exosomes delivering miR‐146a‐5p reinstate mitochondrial function, augment oxidative phosphorylation and ...
Zehui Lv   +13 more
wiley   +1 more source

Osteoblast-derived vesicle protein content is temporally regulated during osteogenesis: Implications for regenerative therapies [PDF]

open access: yes, 2019
Osteoblast-derived extracellular vesicles (EV) are a collection of secreted (sEVs) and matrix-bound nanoparticles that function as foci for mineral nucleation and accumulation.
Owen Davies (1253895)   +8 more
core  

Greater osteoblast and endothelial cell adhesion on nanostructured polyethylene and titanium [PDF]

open access: yes, 2010
Theresa Raimondo, Sabrina Puckett, Thomas J WebsterSchool of Engineering and Department of Orthopedics, Brown University, Providence, RI, USAAbstract: Mostly due to desirable mechanical properties (such as high durability and low wear), certain synthetic
Theresa Raimondo   +3 more
core   +1 more source

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