Results 81 to 90 of about 38,017 (252)

Osteoarthritic cartilage chondrocytes alter subchondral bone osteoblast\ud differentiation via MAPK signalling pathway involving ERK1/2

, 2010
Osteoarthritic subchondral bone is characterized by abnormal bone density and enhanced production of\ud bone turnover markers, an indication of osteoblast dysfunction.
Shi, Wei, Friis, Thor, Prasadam, Indira, Crawford, Ross, Xiao, Yin, van Gennip, Stijn   +5 more
core   +1 more source

Ion‐Driven Regulation of Ca2+ Flow by Ti/Zn Composite Activates ERK/MAPK Signaling and Maintains Mitochondrial Homeostasis to Promote Macrophage‐Mediated Bone Regeneration

Advanced Science, EarlyView.
A 3D‐printed interpenetrating Ti/Zn composite enables sustained Zn2+ release to regulate intracellular Ca2+ redistribution, preserve mitochondrial homeostasis, activate ERK/MAPK signaling, and promote M2 macrophage polarization, thereby enhancing osteoimmune‐mediated bone regeneration and peri‐implant osseointegration.
Wanyi Huang, Qiyue Zhang, Yueyang Qiu, Haocheng Suo, Zengqian Liu, Bing Bai, Qiang Wang, Qing Zhou   +7 more
wiley   +1 more source

TFEB-mediated autophagy stimulation as an anabolic strategy for bone: insights from TFEB activation in the osteoblast lineage

Autophagy Reports
Autophagy in the osteoblast lineage is essential for bone formation and skeletal homeostasis, yet the mechanisms through which it supports bone formation remain unclear.
Melda Onal
doaj   +1 more source

The Enkephalinergic Osteoblast [PDF]

Journal of Bone and Mineral Research, 1998
H, Rosen, A, Krichevsky, Z, Bar-Shavit
openaire   +2 more sources

Premature Osteoblast Clustering by Enamel Matrix Proteins Induces Osteoblast Differentiation through Up-Regulation of Connexin 43 and N-Cadherin [PDF]

, 2011
In recent years, enamel matrix derivative (EMD) has garnered much interest in the dental field for its apparent bioactivity that stimulates regeneration of periodontal tissues including periodontal ligament, cementum and alveolar bone.
Zhang, Yufeng, Buser Daniel, Hedbom Erik, Gemperli Anja C., Ruggiero, Sabrina, Mauth Corinna, Ruggiero Sabrina, Gemperli, Anja C, Yufeng Zhang, Tateyuki Iizuka, Daniel Buser, Miron, Richard, Bosshardt Dieter D., Richard J. Miron, Anja C. Gemperli, Iizuka Tateyuki, Richard J Miron, Erik Hedbom, Corinna Mauth, Sculean Anton, Iizuka, Tateyuki, Anton Sculean, Hedbom, Erik, Zhang Yufeng, Sabrina Ruggiero, Miron Richard J., Buser, Daniel, Anja C Gemperli, Dieter D Bosshardt, Sculean, Anton, Mauth, Corinna, Bosshardt, Dieter, Dieter D. Bosshardt   +32 more
core   +3 more sources

Engineered Xenogeneic Bone Scaffold with IL‐10 Nanodelivery System: Immunomodulation and BMSC Fate Programming for Skull Defect Repair

Advanced Science, EarlyView.
A multifunctional regenerative composite is constructed by 3D‐printing thermosensitive PNIPAM hydrogel embedded with MPDA@IL‐10 nanoparticles and autologous BMSCs onto antigen‐depleted porcine bone matrix for beagle critical‐sized skull defect reconstruction.
Weihao Lv, Lei Zhang, Fei Fei, Zhibin Wu, Xiuquan Wu, Ya‐nan Dou, Yihao Fu, Hao Chang, Yujie Qiang, Huaxia Xie, Ni An, Leiying Chen, Hongchen Zhang, Min‐Wen Zheng, Hongqing Chen, Xia Li, Zhou Fei   +16 more
wiley   +1 more source

Effects of an antibacterial membrane on osteoblast-like cells in vitro

, 2011
Jun Ye1, Qianqian Yao1, Anchun Mo2, Jing Nie2, Wenwen Liu1, Cui Ye1, Xianji Chen11State Key Laboratory of Oral Diseases, 2Department of Oral Implant, West China College of Stomatology, Sichuan University, Chengdu, People's Republic of ...
Xianji Chen, Qianqian Yao, Ye C, Mo A, Nie J, Yao Q, Wenwen Liu, Liu W, Mo Anchun, null Ye, Jing Nie, Chen X, null Cui Ye, Ye J   +13 more
core   +1 more source

Bioadhesive‐Integrated 3D‐Printed Multilayer Scaffolds Secure a Mechanically‐Stable Osteoimmune Niche for Enhanced Bone Augmentation

Advanced Science, EarlyView.
A 3D‑printed multilayer adhesive scaffold, firmly anchored to bone defects by simple finger pressing, suppresses micromotion and secures mechanical stability of the osteogenic niche. This stabilization likely contributes to the enhanced bone augmentation by fostering a pro‑regenerative mechano‐immune profile—characterized by M2‑like macrophage ...
Delu Zhao, Qiuyi Li, Lingyun Wang, Chongao Zhang, Yutian Cheng, Shuang Liu, Fulan Wei, Zheqin Dong   +7 more
wiley   +1 more source

Purinergic signalling in osteoblasts

Frontiers in Bioscience, 2012
The skeleton is maintained throughout life via the finely tuned actions of osteoblasts and osteoclasts, with disruption in this balance eventually leading to bone disease. The exact mechanisms balancing these actions are not fully known, although several regulatory systems are known to be involved.
Gartland, Alison, Orriss, Isabel R., Rumney, Robin M.H., Bond, Alistair P., Arnett, Timothy, Gallagher, James A.   +5 more
openaire   +3 more sources

Self-assembling peptide-enriched electrospun polycaprolactone scaffolds promote the h-osteoblast adhesion and modulate differentiation-associated gene expression [PDF]

, 2012
Electrospun polycaprolactone (PCL) is able to support the adhesion and growth of h-osteoblasts and to delay their degradation rate to a greater extent with respect to other polyesters. The drawbacks linked to its employment in regenerative medicine arise
V. Samouillan, Brun, Paola, Castagliuolo, Ignazio, Brun P, Iucci, Giovanna, Brunelli K, Delaunay, Florian, Roso, Martina, Dettin, Monica, Danesin, Roberta, Samouillan, Valérie, G. Iucci, Delaunay F, Ghezzo, Francesca, Samouillan V, Ghezzo F, Castagliuolo I, F. Delaunay, Dettin M., Roso M, Modesti M, Modesti, Michele, Danesin R, Brunelli, Katya   +23 more
core   +1 more source