Results 231 to 240 of about 197,424 (329)

Self‐Assembled Myricetin‐Arginine Conjugate Nanozymes for Targeted Suppression of Joint Inflammation and Osteoclastogenesis in Rheumatoid Arthritis

Advanced Science, EarlyView.
Carrier‐free myricetin‐arginine conjugate nanozymes (MANZs) have been fabricated through a Mannich reaction and spontaneous self‐assembly. MANZs selectively accumulate in inflamed joints by targeting M1 macrophages via CAT2‐mediated uptake. The nanozymes can effectively modulate macrophage polarization, suppress osteoclast differentiation, and mitigate
Jiachang Hong, Penghao Ji, Jinxi An, Junchao Huang, Ziheng Bu, Xudong Zhang, Wei Liu, Tingyu Wu, Sen Wang, Wei Zhu, Yuhui Li, Jixian Wan, Sudan Xu, Minfeng Huo, Peng Wu   +14 more
wiley   +1 more source

Vildagliptin and Omarigliptin Differentially Bind to DPP-4 Homodimers and Modulate Osteoclast-Mediated Bone Resorption. [PDF]

Compr Physiol
Aeimlapa R, Panmanee J, Teerapornpuntakit J, Wongdee K, Thongbunchoo J, Panupinthu N, Svasti S, Apaijai N, Sa-Nguanmoo P, Chattipakorn S, Chattipakorn N, Charoenphandhu N.   +11 more
europepmc   +1 more source

Mineralized matrix deposition by marrow stromal osteoblasts in 3D perfusion culture increases with increasing fluid shear forces

, 2003
Vassilios I. Sikavitsas, Gregory N. Bancroft, Heidi L. Holtorf, John A. Jansen, Antonios G. Mikos   +4 more
openalex   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

Advanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang, Tao Zhang, Yuan Chen, Nikolaos Kourkoumelis, Mo Chen, Jiale Dong, Zhenyu Li, Yanling Zhou, Ning Li, Chen Zhu, Xifu Shang, Jiaxiang Bai, Xianzuo Zhang   +12 more
wiley   +1 more source

WNT16 Overexpression is Insufficient to Counteract Inflammation-induced Bone Loss in Female Mice. [PDF]

Calcif Tissue Int
Nilsson KH, Henning P, Lagerquist MK, Wu J, Bally M, Lerner UH, Gjertsson I, Ohlsson C, Movérare-Skrtic S.   +8 more
europepmc   +1 more source

Wnt signaling and cellular metabolism in osteoblasts

, 2016
Courtney M. Karner, Fanxin Long
openalex   +1 more source

CGRP Enhances the Regeneration of Bone Defects by Regulating Bone Marrow Mesenchymal Stem Cells Through Promoting ANGPTL4 Secretion by Bone Blood Vessels

Advanced Science, EarlyView.
ABSTRACT Bone angiogenesis is important for bone formation and regeneration after bone injury. Endothelial‐derived angiogenic factors are key signal transducers in the bone microenvironment and maintain vascular–osteogenic coupling during bone regeneration.
Qiong Lu, Qiyue Zheng, Zhaokai Zhou, Yajun Chen, Yun Chen, Wenjie Chen, Jiaojiao Wang, Ren Guo, Ren Wu, Lina Chen   +9 more
wiley   +1 more source

Progress on the mechanism of Polycystin-1 in bone remodeling. [PDF]

Front Cell Dev Biol
Guo J, Hu G, Li X, Yi X, Chang B, Li T.
europepmc   +1 more source

A Universal Metal–Flavonoid Coating Strategy: Engineering Biomaterials for Diabetic Bone Regeneration

Advanced Science, EarlyView.
Construction of metal–flavonoid functionalized coatings on conventional bone repair materials. A one‐pot method is used to directly construct multifunctional metal–flavonoid coatings on the surface of traditional bone repair materials by selecting metal ions with osteogenic/angiogenic properties and flavonoids with reactive oxygen species scavenging ...
Chen Yang, Chenle Dong, Lefeng Su, Zhiqiang Liu, Lingyi Hu, Qishu Jin, Hao Chen, Chunlong Zhang, Yihao Wu, Jiang Chang, Zhaowenbin Zhang, Jiandong Yuan   +11 more
wiley   +1 more source

Complete Blood Count Parameters and Bone Health: Clinical and Experimental Evidence. [PDF]

Endocrinol Metab (Seoul)
Ha J, Ono M, Zhu H, Cencer C, Ge X, Wu JY.   +5 more
europepmc   +1 more source