Results 11 to 20 of about 2,079,758 (368)
Osteoblast Differentiation at a Glance [PDF]
Medical Science Monitor Basic Research, 2016 Ossification is a tightly regulated process, performed by specialized cells called osteoblasts. Dysregulation of this process may cause inadequate or excessive mineralization of bones or ectopic calcification, all of which have grave consequences for ...
A. Rutkovskiy, K. Stensløkken, I. Vaage
semanticscholar +3 more sources
p38 MAPK Signaling in Osteoblast Differentiation [PDF]
Frontiers in Cell and Developmental Biology, 2016 The skeleton is a highly dynamic tissue whose structure relies on the balance between bone deposition and resorption. This equilibrium, which depends on osteoblast and osteoclast functions, is controlled by multiple factors that can be modulated post ...
Eddie Rodríguez-Carballo +2 more
semanticscholar +5 more sources
Bioenergetic Metabolism In Osteoblast Differentiation
Current Osteoporosis Reports, 2022 Osteoblasts are responsible for bone matrix production during bone development and homeostasis. Much is known about the transcriptional regulation and signaling pathways governing osteoblast differentiation. However, less is known about how osteoblasts obtain or utilize nutrients to fulfill the energetic demands associated with osteoblast ...
Leyao Shen, G. Hu, Courtney M. Karner
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miR-452-3p inhibited osteoblast differentiation by targeting Smad4 [PDF]
PeerJ, 2021 Osteoblast differentiation is a complex process that is essential for normal bone formation. A growing number of studies have shown that microRNAs (miRNAs) are key regulators in a variety of physiological and pathological processes, including ...
Ming Wu +6 more
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Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
, 2017 Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
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Frontiers in Endocrinology, 2021 Neural cell adhesion molecule (NCAM) is involved in cell multi-directional differentiation, but its role in osteoblast differentiation is still poorly understood.
Bin-Feng Cheng +10 more
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Regulation of Osteoblast Differentiation by Cytokine Networks
International Journal of Molecular Sciences, 2021 Osteoblasts, which are bone-forming cells, play pivotal roles in bone modeling and remodeling. Osteoblast differentiation, also known as osteoblastogenesis, is orchestrated by transcription factors, such as runt-related transcription factor 1/2, osterix,
Dulshara Sachini Amarasekara +2 more
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Osteoblast Differentiation and Signaling: Established Concepts and Emerging Topics
International Journal of Molecular Sciences, 2021 Osteoblasts, the cells that build up our skeleton, are remarkably versatile and important cells that need tight regulation in all the phases of their differentiation to guarantee proper skeletal development and homeostasis.
M. Ponzetti, N. Rucci
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Autophagy, 2022 Maintenance of bone integrity is mediated by the balanced actions of osteoblasts and osteoclasts. Because macroautophagy/autophagy regulates osteoblast mineralization, osteoclast differentiation, and their secretion from osteoclast cells, autophagy ...
G. Yoshida +13 more
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BMP-2 Induced Expression of Alx3 That Is a Positive Regulator of Osteoblast Differentiation. [PDF]
PLoS ONE, 2013 Bone morphogenetic proteins (BMPs) regulate many aspects of skeletal development, including osteoblast and chondrocyte differentiation, cartilage and bone formation, and cranial and limb development.
Takashi Matsumoto +10 more
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