Role of galectin-3 in bone cell differentiation, bone pathophysiology and vascular osteogenesis [PDF]
Galectin-3 is expressed in various tissues, including the bone, where it is considered a marker of chondrogenic and osteogenic cell lineages. Galectin-3 protein was found to be increased in the differentiated chondrocytes of the metaphyseal plate ...
Fantauzzi, Claudia Blasetti +3 more
core +2 more sources
Gastric carcinoma with osteoblastic differentiation
Carcinosarcoma is a rare malignant biphasic tumor which has sarcomatous and carcinomatous components. Stomach localization is very rare. We discuss the diagnosis, follow-up and treatment of patients diagnosed with gastric carcinosarcoma in company with the literature review.A 73-year-old white male patient applied to hospital with dyspeptic complaints ...
Selcukbiricik, Fatih +4 more
openaire +2 more sources
Proteomic Analysis of Human Osteoblastic Cells: Relevant Proteins and Functional Categories for Differentiation [PDF]
Osteoblasts are the bone forming cells, capable of secreting an extracellular matrix with mineralization potential. The exact mechanism by which osteoblasts differentiate and form a mineralized extracellular matrix is presently not fully understood.
Alves, R.D.A.M. (Rodrigo) +7 more
core +1 more source
Osteoblast differentiation and migration are regulated by Dynamin GTPase activity [PDF]
Bone formation is controlled by osteoblasts but the signaling proteins that control osteoblast differentiation and function are still unclear. We examined if the dynamin GTPase, which is associated with actin remodeling and migration in other cells ...
Bruzzaniti, Angela +4 more
core +2 more sources
IGFBP-2 Directly Stimulates Osteoblast Differentiation [PDF]
ABSTRACT Insulin-like growth factor binding protein 2 (IGFBP-2) is important for acquisition of normal bone mass in mice; however, the mechanism by which IGFBP-2 functions is not defined. These studies investigated the role of IGFBP-2 in stimulating osteoblast differentiation.
Gang, Xi +4 more
openaire +2 more sources
Changes in PGE2 signaling after submandibulectomy alter post–tooth extraction socket healing [PDF]
Saliva is very important to oral health, and a salivary deficit has been shown to bring serious problems to oral health. There is scant information about the mechanisms through which salivary glands participate in post–tooth extraction socket healing ...
Bozzini, Clarisa +5 more
core +1 more source
Cyclophilin E (CypE) belongs to the cyclophilin family and exhibits peptidyl-prolyl cis-trans isomerase (PPIase) activity. It participates in various biological processes through the regulation of peptidyl-prolyl isomerization. However, the specific role
Meiyu Piao +5 more
doaj +1 more source
Mathematical modelling of the pathogenesis of multiple myeloma-induced bone disease [PDF]
Multiple myeloma (MM) is the second most common haematological malignancy and results in destructive bone lesions. The interaction between MM cells and the bone microenvironment plays an important role in the development of the tumour cells and MM ...
Blum B +6 more
core +1 more source
JAK2-STAT5B pathway and osteoblast differentiation [PDF]
Osteoblast differentiation is a critical step in the maintenance of bone homeostasis. Osteoblast differentiation is generally maintained by growth hormone (GH) and various other endocrine and autocrine/paracrine factors. JAK2-STAT5B pathway is a central axis in the mechanism of GH signaling.
Darvin, Pramod +2 more
openaire +2 more sources
Double acid etching treatment of dental implants for enhanced biological properties [PDF]
Background: The topographical features on the surface of dental implants have been considered as a critical parameter for enhancing the osseointegration of implants.
Delgado, Luis M. +6 more
core +2 more sources

