Results 51 to 60 of about 71,796 (264)

Light‐Assisted 3D Printing Techniques and Photocrosslinking Strategies: Recent Advances in Musculoskeletal Tissue Engineering

Advanced Engineering Materials, EarlyView.
In this review, the current state of light‐assisted 3D printing as it pertains to engineering musculoskeletal tissues including bone, cartilage, skeletal muscle, tendon, and ligaments is summarized. Common printing techniques, photoreactive materials, and study design choices are compiled and reviewed.
Meagan Morgan, Bin Zhang, Roger Narayan
wiley   +1 more source

A microRNA regulatory mechanism of osteoblast differentiation [PDF]

Proceedings of the National Academy of Sciences, 2009
Growing evidence shows that microRNAs (miRNAs) regulate various developmental and homeostatic events in vertebrates and invertebrates. Osteoblast differentiation is a key step in proper skeletal development and acquisition of bone mass; however, the physiological role of non-coding small RNAs, especially miRNAs, in osteoblast differentiation remains ...
Hiroyuki, Inose, Hiroki, Ochi, Ayako, Kimura, Koji, Fujita, Ren, Xu, Shingo, Sato, Makiko, Iwasaki, Satoko, Sunamura, Yasuhiro, Takeuchi, Seiji, Fukumoto, Kuniaki, Saito, Takashi, Nakamura, Haruhiko, Siomi, Hiroshi, Ito, Yoshiyasu, Arai, Ken-ichi, Shinomiya, Shu, Takeda   +16 more
openaire   +2 more sources

Magnesium‐Based Transient Bioelectronics, Bio‐Optics and Bio‐Scaffolds

Advanced Functional Materials, EarlyView.
This paper reviews the state of the art and recent advances in magnesium‐based thin‐film, foils, and scaffolds for applications in transient bio‐optics, bioelectronics and tissue engineering. The design principles, fabrication methods, material properties, and integration strategies are discussed in detail.
Massimo Mariello, Yves Leterrier
wiley   +1 more source

Eucommia ulmoides Oliver polysaccharide alleviates glucocorticoid-induced osteoporosis by stimulating bone formation via ERK/BMP-2/SMAD signaling

Scientific Reports
Osteoporosis (OP) is a metabolic disease characterized by low bone mineral mass owing to osteoblast dysfunction. Eucommia ulmoides Oliver (EuO) is a Chinese herbal medicine traditionally used to treat OP.
Jiyu Song, Yongfeng Zhang, Xinghui Jin, Yanfeng Zhu, Yutong Li, Min Hu   +5 more
doaj   +1 more source

Hedgehog signaling in tumor cells facilitates osteoblast-enhanced osteolytic metastases. [PDF]

PLoS ONE, 2012
The remodeling process in bone yields numerous cytokines and chemokines that mediate crosstalk between osteoblasts and osteoclasts and also serve to attract and support metastatic tumor cells.
Shamik Das, J Allan Tucker, Shikha Khullar, Rajeev S Samant, Lalita A Shevde   +4 more
doaj   +1 more source

Effect of asymmetric dimethylarginine on osteoblastic differentiation [PDF]

Kidney International, 2001
Asymmetric dimethylarginine (ADMA) is an endogenous inhibitor of nitric oxide synthase (NOS) that accumulates in renal insufficiency and may be a uremic toxin. To determine whether ADMA inhibits bone metabolism, we investigated the in vitro effect of ADMA on osteoblastic differentiation in mouse bone marrow-derived mesenchymal stem cells (BMSCs).The ...
Xiao, Z. Sheng, Quarles, L. Darryl, Chen, Q. Quan, Yu, Y. Hui, Qu, X. Ping, Jiang, C. Hong, Deng, H. Wu, Li, Y. Jian, Zhou, H. Hao   +8 more
openaire   +2 more sources

Therapeutic Extracellular Vesicles from Synovial Fibroblast‐Primed MSCs for Osteoarthritis Treatment

Advanced Healthcare Materials, EarlyView.
EVs derived from the microenvironment of SFs transferred MSCs (miSF‐MSC‐EVs) enhanced the expression of miRNAs that regulate cell migration, cell adhesion, and the TGF‐β signaling pathway, demonstrating superior anti‐inflammatory and cartilage regeneration effects compared to conventional MSC‐EVs.
Seo Jeong Kim, Ji Seob Kim, Min Hee Moon, Jae‐Hyeok Jang, In Sun Hwang, Byung‐Hyun Cha   +5 more
wiley   +1 more source

Fibronectin regulates calvarial osteoblast differentiation [PDF]

Journal of Cell Science, 1996
ABSTRACT The secretion of fibronectin by differentiating osteoblasts and its accumulation at sites of osteogenesis suggest that fibronectin participates in bone formation. To test this directly, we determined whether fibronectin-cell interactions regulate progressive differentiation of cultured fetal rat calvarial osteoblasts.
A M, Moursi, C H, Damsky, J, Lull, D, Zimmerman, S B, Doty, S, Aota, R K, Globus   +6 more
openaire   +2 more sources

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

BMP2-dependent gene regulatory network analysis reveals Klf4 as a novel transcription factor of osteoblast differentiation

Cell Death and Disease, 2021
Transcription factors (TFs) regulate the expression of target genes, inducing changes in cell morphology or activities needed for cell fate determination and differentiation.
Shuaitong Yu, Jinqiang Guo, Zheyi Sun, Chujiao Lin, Huangheng Tao, Qian Zhang, Yu Cui, Huanyan Zuo, Yuxiu Lin, Shuo Chen, Huan Liu, Zhi Chen   +11 more
doaj   +1 more source