Results 21 to 30 of about 71,796 (264)
Biphasic regulation of osteoblast development via the ERK MAPK–mTOR pathway
eLife, 2022 Emerging evidence supports that osteogenic differentiation of skeletal progenitors is a key determinant of overall bone formation and bone mass. Despite extensive studies showing the function of mitogen-activated protein kinases (MAPKs) in osteoblast ...
Jung-Min Kim +8 more
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BMC Musculoskeletal Disorders, 2020 Background The differentiation of human stromal (mesenchymal) stem cells (hMSCs) is a critical procedure for the development of osteoblast. SNHG14 is a newly discovered lncRNA that has been barely studied.
Mingchang Du +5 more
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BMC Oral Health, 2021 Background The dentin is a tissue, which is formed by odontoblasts at the pulp interface of the teeth that supports the enamel. Odontoblasts, the cranial neural crest cells are derived from ectodermal mesenchymal stem cells (MSCs) and are long and ...
Young-Bum Son +8 more
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eLife, 2022 Cellular differentiation is associated with the acquisition of a unique protein signature that is essential to attain the ultimate cellular function and activity of the differentiated cell.
Leyao Shen +5 more
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Gastric carcinoma with osteoblastic differentiation
International Journal of Surgery Case Reports, 2012 Carcinosarcoma is a rare malignant biphasic tumor which has sarcomatous and carcinomatous components. Stomach localization is very rare. We discuss the diagnosis, follow-up and treatment of patients diagnosed with gastric carcinosarcoma in company with the literature review.A 73-year-old white male patient applied to hospital with dyspeptic complaints ...
Selcukbiricik, Fatih +4 more
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The Roles of SNHG Family in Osteoblast Differentiation
Genes, 2022 Small nucleolar RNA host genes (SNHGs), members of long-chain noncoding RNAs (lncRNAs), have received increasing attention regarding their roles in multiple bone diseases. Studies have revealed that SNHGs display unique expression profile during osteoblast differentiation and that they could act as promising biomarkers of certain bone diseases, such as
Tan, An-Qi, Zheng, Yun-Fei
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The effects of Omarigliptin on promoting osteoblastic differentiation [PDF]
Bioengineered, 2021 Osteoporosis significantly impacts the normal life of the elderly and is reported to be closely related to dysfunction of osteoblastic differentiation. Runt-related transcription factor-2 (Runx2) is a critical transcriptional factor involved in the regulation of osteoblast differentiation.
Fake Liao, Xiunian Hu, Rijiang Chen
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Cells, 2023 Cyclophilin E (CypE) belongs to the cyclophilin family and exhibits peptidyl-prolyl cis-trans isomerase (PPIase) activity. It participates in various biological processes through the regulation of peptidyl-prolyl isomerization. However, the specific role
Meiyu Piao +5 more
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Indirect osteoblast differentiation by liposomal clodronate [PDF]
Journal of Cellular and Molecular Medicine, 2017 AbstractBisphosphonates impair function of osteoclasts and prevent bone resorption, the mechanism of which has been studied extensively. However, the possible effects of bisphosphonates on chondroblast differentiation and calcium deposition by osteoblasts have only been demonstrated recently.
Emi Okada +4 more
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Wdr5 Is Essential for Osteoblast Differentiation
Journal of Biological Chemistry, 2008 Wdr5 is developmentally expressed in osteoblasts and accelerates osteoblast differentiation in vitro and in vivo. To address whether Wdr5 is essential for osteoblast differentiation, plasmid-based small interfering RNAs were used to stably suppress endogenous Wdr5 protein levels in MC3T3-E1 cells.
Eric D, Zhu +2 more
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