Results 31 to 40 of about 1,211,688 (156)

Technical Case Report of a Cranioplasty With ex vivo Frozen Ostoblastic Bone Graft From Large Skull Metastasis

open access: yesFrontiers in Surgery, 2021
Objective: Liquid nitrogen cryotherapy has shown efficacy in the treatment of bone tumors of the extremities with good oncologic and functional outcomes.
Pang-Shuo Perng   +7 more
doaj   +1 more source

Exosomes derived from osteogenic tumor activate osteoclast differentiation and concurrently inhibit osteogenesis by transferring COL1A1‐targeting miRNA‐92a‐1‐5p

open access: yesJournal of Extracellular Vesicles, 2021
In patients with prostate cancer (PCa), bone lesions appear osteoblastic in radiographs; however, pathological fractures frequently occur in PCa patients, and bone resorption is observed in all metastatic lesions under histopathologic assessment.
Lijuan Yu   +10 more
doaj   +1 more source

Pseudoprogression after advanced first-line endocrine therapy in metastatic breast cancer with bone metastasis: A case report

open access: yesFrontiers in Oncology, 2023
Approximately 75% of patients with advanced breast cancer develop bone metastasis, which significantly affects both the quality of life and the survival rate of patients. Accurate determination of the status of bone metastases is important for developing
Aijuan Tian   +6 more
doaj   +1 more source

Research Progress of Tumor Microenvironment and Prostate Cancer Bone Metastasis

open access: yesZhongliu Fangzhi Yanjiu, 2018
The majority of prostate cancer (PCa)-induced deaths is due to the development of metastatic disease, 80% of which is primarily localized in the bone. The types of bone metastasis of PCa are mainly osteoblastic or osteoclastic lesions.
MENG Jie, LU Yi, ZHANG Jian
doaj   +1 more source

Disseminated Mixed Lytic‐Sclerotic Skeletal Metastases as Initial Presentation of Gallbladder Carcinoma: A Case Report [PDF]

open access: yesClin Case Rep
ABSTRACT Gallbladder carcinoma is an aggressive malignancy often diagnosed at an advanced stage. Skeletal metastasis, especially mixed lytic‐sclerotic lesions, is rare and typically occurs late. This report highlights an unusual presentation where widespread bony metastases were the initial manifestation, leading to the diagnosis of gallbladder ...
Rao S, Adhikari B, Khatiwada A.
europepmc   +2 more sources

Regulation of bone homeostasis by MERTK and TYRO3

open access: yesNature Communications, 2022
The TAM family of receptor tyrosine kinases exerts pleiotropic functions in health and disease. Here, the authors show that TAM receptors control osteoblastic bone formation and identified MERTK as a novel target for bone anabolic therapy and mitigation ...
Janik Engelmann   +20 more
doaj   +1 more source

Calvarial Bone Implantation and in vivo Imaging of Tumor Cells in Mice

open access: yesBio-Protocol, 2019
Bone is one of common metastasis sites for many types of cancer. In bone metastatic microenvironment, tumor-bone interactions play a significant role in the regulation of osteolytic or osteoblastic bone metastasis.
Kyoko Hashimoto   +4 more
doaj   +1 more source

Roles of renin-angiotensin system in the regulation of prostate cancer bone metastasis: a critical review

open access: yesAnnals of Urologic Oncology, 2021
Mestastatic prostate cancer cells (MPCCs) frequently metastasize to bone, which is a “favorite soil” for colonization and proliferation of MPCCs. Prostate cancer bone mestastasis is tightly associated with tumor-induced bone lesions, most commonly caused
Manh Tien Tran
doaj   +1 more source

An unusual case of osteoblastic metastasis from gastric carcinoma.

open access: yes, 2002
We report an unusual case of osteoblastic metastasis from gastric carcinoma. In this case, bone metastasis was the initial manifestation of the cancer. The laboratory findings revealed mild hypocalcemia and markedly elevated alkaline phosphatase levels ...
Choi, TY   +6 more
core   +1 more source

Metastatic Lung Adenocarcinoma to the Uterus Mimicking a Primary Uterine Malignancy: A Case Report [PDF]

open access: yesCancer Rep (Hoboken)
ABSTRACT Background Lung adenocarcinoma is the most prevalent subtype of non‐small cell lung cancer and exhibits a high tendency for distant metastasis. However, uterine metastasis with synchronous multiorgan involvement is extremely rare and prone to misdiagnosis due to atypical clinical presentations.
Sun P, Wang Y.
europepmc   +2 more sources

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