Results 151 to 160 of about 4,458,897 (200)
Some of the next articles are maybe not open access.
Pinacidil stimulates osteoblast function in osteoblastic MC3T3-E1 cells
Immunopharmacology and Immunotoxicology, 2013This study examined the effect of pinacidil, a nonselective adenosine triphosphate-sensitive potassium channel opener, on the function of osteoblastic MC3T3-E1 cells. Pinacidil caused a significant elevation of collagen synthesis, alkaline phosphatase activity, osteocalcin synthesis and mineralization in the cells (p
Kwang Sik, Suh +2 more
openaire +2 more sources
Osteoblastic cells: Differentiation and trans-differentiation
Archives of Biochemistry and Biophysics, 2008The osteoblast is the bone forming cell and is derived from mesenchymal stem cells (MSC) present among the bone marrow stroma. MSC are capable of multi-lineage differentiation into mesoderm-type cells such as osteoblasts and adipocytes. Understanding the mechanisms underlying osteoblast differentiation from MSC is a central topic in bone biology that ...
Kassem, Moustapha +2 more
openaire +2 more sources
Study of osteoblastic cells in a microfluidic environment
Biomaterials, 2006Bone tissue engineering consists of culturing osteoblastic cells onto synthetic three-dimensional (3D) porous scaffolds. The organization of bone cells into 3D scaffolds is crucial for ex vivo tissue formation. Diffusional rates of nutrients could be greatly improved by perfusing media through the 3D microporous scaffolds.
Leclerc, E. +6 more
openaire +3 more sources
Estrogen modulation of osteoblastic cell-to-cell communication
Journal of Cellular Biochemistry, 1998Two osteoblastic cell populations, calvarial and marrow stromal cells, were exposed to estrogen derivatives in vitro. The hormonal effect was monitored by following intracellular Ca+2 levels [Ca+2]i and gap-junction communication. We measured fast changes in intracellular Ca+2 levels in response, of these cells, to the steroid hormones.
R, Massas, R, Korenstein, D, Benayahu
openaire +2 more sources
Collagenase synthesis by osteoblast-like cells
Calcified Tissue International, 1984Cultures of osteoblast-like cells from a rat sarcoma and osteoblast-enriched populations of rat calvarial cells synthesize and secrete a true collagenase and collagenase inhibitor. The enzyme, which is produced in a latent form, appears to be similar to the enzyme produced by fibroblasts.
K, Otsuka, J, Sodek, H F, Limeback
openaire +2 more sources
Circulating Osteoblast-Lineage Cells in Humans
New England Journal of Medicine, 2005Although current evidence suggests that only a minuscule number of osteoblast-lineage cells are present in peripheral blood, we hypothesized that such cells circulate but that their concentration has been vastly underestimated owing to the use of assays that required adherence to plastic.
Guiti Z, Eghbali-Fatourechi +5 more
openaire +2 more sources
Osteoblastic metastases in renal cell carcinoma
The British Journal of Radiology, 1981Renal cell carcinoma (hypernephroma, renal adenocarcinoma) metastasizes to the skeleton in approximately 10% of cases and characteristically produces expansile lytic lesions (Forbes et al., 1977). Although sclerotic changes may be seen following radiotherapy, osteosclerotic metastases in this condition prior to therapy are virtually unknown (Forbes et ...
A I, Neugut +3 more
openaire +2 more sources
Effects of risedronate on osteoblastic cell cultures
Archives of Oral Biology, 2016Bisphosphonates (BPs) have been widely used in the treatment of bone disorders due to their ability to modulate bone turnover. The biological mechanisms through BFs exert their effects on osteoclasts are well established. However, the role of BFs on the osteoblasts is controversial.
Maurilio, Malavasi +7 more
openaire +2 more sources
The Intrinsic Incompressibility of Osteoblast-like Cells
Tissue Engineering, 1996This paper presents a new methodology, apparatus design, and the experimental results of ongoing research into the measurement of the mechanical properties of musculoskeletal tissue at the cellular level. A microchamber was constructed that provides a controlled hydrostatic pressure environment for these cells where optical sectioning, via ...
R P, Wilkes, K A, Athanasiou
openaire +2 more sources
Steroid Sulfatase Activity in Osteoblast Cells
Biochemical and Biophysical Research Communications, 1997We have demonstrated steroid sulfatase activity in osteoblast cells and characteristics of the enzyme were also investigated. Cell free homogenate of rat osteoblast cell line, UMR106-01 and human osteoblast cell lines, MG-63, HOS were incubated with [3H] dehydroepiandrosterone-sulfate (DHEA-sulfate) or [3H] estrone-sulfate (E1-sulfate).
H, Fujikawa +7 more
openaire +2 more sources