Results 1 to 10 of about 1,211,688 (156)

The role of prostate-specific antigen in the osteoblastic bone metastasis of prostate cancer: a literature review [PDF]

Frontiers in Oncology, 2023
Prostate cancer is the only human malignancy that generates predominantly osteoblastic bone metastases, and osteoblastic bone metastases account for more than 90% of osseous metastases of prostate cancer.
Xu Zhang, Peng Jiang, Chaojun Wang
doaj   +6 more sources

Changes in Osteoblastic Bone Metastasis Detected Incidentally by Cone-Beam Computed Tomography: A Case Report [PDF]

Case Reports in Oncology
Introduction: Although cone-beam computed tomography (CBCT) is essential for tumor positioning in image-guided radiotherapy, its diagnostic application is limited by low image quality.
Uchina Hiya, Masashi Endo, Kohei Okada, Satoru Takahashi, Kazunari Ogawa, Machi Nakagawa, Michiko Nakamura, Chiaki Shibayama, Yukiko Fukuda, Keiko Akahane, Masahiro Kawahara, Harushi Mori, Katsuyuki Shirai   +12 more
doaj   +3 more sources

Canine prostatic cancer cell line (LuMa) with osteoblastic bone metastasis [PDF]

Prostate, 2020
Background Osteoblastic bone metastasis represents the most common complication in men with prostate cancer (PCa). During progression and bone metastasis, PCa cells acquire properties similar to bone cells in a phenomenon called osteomimicry, which ...
Said M Elshafae, Wachiraphan Supsavhad, Aylin A Demirer   +2 more
exaly   +3 more sources

Proteoglycans as Molecular Regulators of Bone Metastasis: Extracellular Matrix Remodeling, Tumor–Bone Crosstalk, Dormancy, and Therapeutic Opportunities [PDF]

Biomolecules
Background: Bone metastasis is a frequent and debilitating complication of advanced cancer, particularly in breast and prostate cancer, and is driven by complex interactions among tumor cells, bone-resident cells, immune populations, vascular components,
Zoila Mora Guzmán, Ibzan Jahzeel Salvador Ibarra, Patricia Juárez, Anahí Jobeth Borrás Enríquez, Edmar de Jésús Díaz García, Hector Alejandro Cabrera-Fuentes, María Teresa Hernández-Huerta   +6 more
doaj   +3 more sources

A case of ROS1-rearranged lung adenocarcinoma with osteoblastic bone metastasis [PDF]

Respiratory Medicine Case Reports, 2020
A 53-year-old woman was referred to our hospital for detailed examination of abnormal chest shadows recognized on CT imaging. Transbronchial lung biopsy of a right S6 nodular shadow led to a diagnosis of lung adenocarcinoma.
Yutaka Takahara, Kouichi Yamamura, Saki Matsuura, Takashi Sakuma, Kazuaki Nishiki, Keisuke Nakase, Masafumi Nojiri, Ryo Kato, Shohei Shinomiya, Rieko Oikawa, Yuki Fujimoto, Taku Oikawa, Kazuhiro Osanai, Yoshimichi Ueda, Shiro Mizuno   +14 more
doaj   +2 more sources

Wnt1 induces osteoblastic changes in a well‐established osteolytic skeletal metastatic model derived from breast cancer

Cancer Reports, 2023
Background Osteoblastic skeletal metastasis is frequently observed in prostate cancer. An effective therapy has not been developed due to the unclear molecular mechanism.
Aya Sugyo, Atsushi B. Tsuji, Hitomi Sudo, Yoshiya Sugiura, Mitsuru Koizumi, Tatsuya Higashi   +5 more
doaj   +2 more sources

Relationship between clinical features and gene mutations in non-small cell lung cancer with osteoblastic bone metastasis

Cancer Treatment and Research Communications, 2021
Objective: Lung cancer patients presenting with osteoblastic bone metastases at the first visit is rare. We investigated the clinical characteristics and gene mutation rate of non-small cell lung cancer patients with osteoblastic bone metastases at the ...
Yutaka Takahara, Keisuke Nakase, Masafumi Nojiri, Ryo Kato, Shohei Shinomiya, Taku Oikawa, Shiro Mizuno   +6 more
doaj   +3 more sources

Antagonizing exosomal miR-18a-5p derived from prostate cancer cells ameliorates metastasis-induced osteoblastic lesions by targeting Hist1h2bc and activating Wnt/β-catenin pathway

Genes and Diseases, 2023
More than 50% of prostate cancer (PCa) patients have bone metastasis with osteoblastic lesions. MiR-18a-5p is associated with the development and metastasis of PCa, but it remains unclear whether it is involved in osteoblastic lesions.
Fanchun Zeng, Chunrong Zhao, Rujie Wang, Lingyan Ren, Hao Qiu, Zhi Zou, Haibin Ding, Zhongyi Sun, Jianmei Li, Shiwu Dong   +9 more
doaj   +3 more sources

Two cases of osteoblastic bone metastasis from muscle-invasive bladder cancer with discrepancy in response to chemotherapy: problems and limitations of bone biopsy [PDF]

International Cancer Conference Journal, 2020
Naoya Masumori, Ko Kobayashi, Toshiaki Tanaka   +2 more
exaly   +2 more sources

Mechanisms of Osteoblastic Bone Metastasis in Prostate Cancer: Role of Prostatic Acid Phosphatase [PDF]

Journal of the Endocrine Society, 2019
Alice C Levine, Mariana Quiroz-Munoz, Dushyanthy Arumugam   +2 more
exaly   +2 more sources