Results 21 to 30 of about 81,269 (285)

Mesenchymal Stem Cell Spheroids Retain Osteogenic Phenotype Through α2β1 Signaling. [PDF]

, 2016
Unlabelled: The induction of mesenchymal stem cells (MSCs) toward the osteoblastic lineage using osteogenic supplements prior to implantation is one approach under examination to enhance their bone-forming potential.
Harvestine, Jenna N, Hoch, Allison I, Leach, J Kent, Murphy, Kaitlin C, Zhou, Dejie   +4 more
core   +1 more source

Involvement of microRNAs in regulation of osteoblastic differentiation in mouse induced pluripotent stem cells. [PDF]

PLoS ONE, 2012
UNLABELLED: BACKGOROUND: MicroRNAs (miRNAs), which regulate biological processes by annealing to the 3'-untranslated region (3'-UTR) of mRNAs to reduce protein synthesis, have been the subject of recent attention as a key regulatory factor in cell ...
Hideharu Okamoto, Yoshiaki Matsumi, Yoshiko Hoshikawa, Kazuko Takubo, Kazuo Ryoke, Goshi Shiota   +5 more
doaj   +1 more source

Single-Cell Transcriptomics Reveals the Complexity of the Tumor Microenvironment of Treatment-Naive Osteosarcoma

Frontiers in Oncology, 2021
Osteosarcoma (OS), which occurs most commonly in adolescents, is associated with a high degree of malignancy and poor prognosis. In order to develop an accurate treatment for OS, a deeper understanding of its complex tumor microenvironment (TME) is ...
Yun Liu, Wenyu Feng, Yan Dai, Yan Dai, Yan Dai, Mengying Bao, Mengying Bao, Mengying Bao, Zhenchao Yuan, Mingwei He, Zhaojie Qin, Shijie Liao, Juliang He, Qian Huang, Zhenyuan Yu, Zhenyuan Yu, Zhenyuan Yu, Yanyu Zeng, Yanyu Zeng, Yanyu Zeng, Binqian Guo, Binqian Guo, Binqian Guo, Rong Huang, Rong Huang, Rong Huang, Rirong Yang, Rirong Yang, Rirong Yang, Yonghua Jiang, Yonghua Jiang, Yonghua Jiang, Jinling Liao, Jinling Liao, Jinling Liao, Zengming Xiao, Xinli Zhan, Chengsen Lin, Jiake Xu, Yu Ye, Yu Ye, Yu Ye, Jie Ma, Qingjun Wei, Qingjun Wei, Zengnan Mo, Zengnan Mo, Zengnan Mo   +47 more
doaj   +1 more source

Primary osteoblasts, osteoblast precursor cells or osteoblast‐like cell lines: Which human cell types are (most) suitable for characterizing 45S5‐bioactive glass? [PDF]

Journal of Biomedical Materials Research Part A, 2019
AbstractThe question how bioactive glasses (BGs) influence the viability and osteogenic differentiation of human osteogenic cells has already been addressed by several studies. However, a literature review revealed great differences in the type of cells used for these experiments.
Sebastian Wilkesmann, Jörg Fellenberg, Qaisar Nawaz, Bruno Reible, Arash Moghaddam, Aldo R. Boccaccini, Fabian Westhauser   +6 more
openaire   +3 more sources

Glial cell line-derived neurotrophic factor influences proliferation of osteoblastic cells [PDF]

, 2012
Little is known about the role of neurotrophic growth factors in bone metabolism. This study investigated the short-term effects of glial cell line-derived neurotrophic factor (GDNF) on calvarial-derived MC3T3-E1 osteoblasts.
Airaksinen, Baldassarre, Ben A. Scheven, Chen, Costantini, Cuccuru, De Ceuninck, Declercq, Edery, Figiel, Forander, Frost, Gale, Gao, Garcia, Gattei, Gattei, Glass, Gowen, Hashino, Hefferan, Hellmich, Janssens, Jiang, Kashani, Krieglstein, Kuno, Kurozumi, Lencel, Li, Luukko, Modrowski, Nakayama, Nanes, Nosrat, Nosrat, Paratcha, Paul R. Cooper, Peterziel, Rawlinson, Remy, Remy, Robinson, Saarma, Sariola, Scheven, Scheven, Shi, Subramaniam, van den Bos, Wang, Wang, Yajima, Yan, Yanaga, Zins, Zoe Gale   +56 more
core   +2 more sources

OSU53 Rescues Human OB-6 Osteoblastic Cells from Dexamethasone through Activating AMPK Signaling.

PLoS ONE, 2016
Excessive dexamethasone (Dex) application causes osteoblast cell death, which could lead to osteoporosis or osteonecrosis. AMP-activated protein kinase (AMPK) activation is shown to protect osteoblasts/osteoblastic cells from Dex.
Dawei Xu, Wei Zhao, Xinhui Zhu, Jianbo Fan, Shengyu Cui, Yuyu Sun, Xiang Chen, Wei Liu, Zhi-Ming Cui   +8 more
doaj   +1 more source

Aplidin (plitidepsin) is a novel anti-myeloma agent with potent anti-resorptive activity mediated by direct effects on osteoclasts [PDF]

, 2019
Despite recent progress in its treatment, Multiple Myeloma (MM) remains incurable and its associated bone disease persists even after complete remission.
Atkinson, Emily G., Bellido, Teresita, Delgado-Calle, Jesus, Galmarini, Carlos Maria, Kurihara, Noriyoshi, Miyagawa, Kazuaki, Nelson, Jessica, Roodman, G. David   +7 more
core   +1 more source

Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferation

Grasas y Aceites, 2014
The aim of this study was, first, to investigate the influence of olive variety and elevation of orchards on the phenolic compound content of Sicilian virgin olive oils (VOOs) and, second, to investigate the effects of VOO phenolic extracts on osteoblast
O. García-Martínez, G. Mazzaglia, A. Sánchez-Ortiz, F. M. Ocaña-Peinado, A. Rivas   +4 more
doaj   +1 more source

Zinc Sulfate Stimulates Osteogenic Phenotypes in Periosteum-Derived Cells and Co-Cultures of Periosteum-Derived Cells and THP-1 Cells

Life, 2021
Coupling between osteoblast-mediated bone formation and osteoclast-mediated bone resorption maintains both mechanical integrity and mineral homeostasis. Zinc is required for the formation, mineralization, growth, and maintenance of bones. We examined the
Jin-Ho Park, Su A Park, Young-Hoon Kang, So Myeong Hwa, Eun-Byeol Koh, Sun-Chul Hwang, Se Heang Oh, June-Ho Byun   +7 more
doaj   +1 more source

Polarity of Osteoblasts and Osteoblast-like UMR-108 Cells

Journal of Bone and Mineral Research, 1999
Abstract Enveloped viruses, such as vesicular stomatitis virus (VSV) and Influenza virus, have been widely used in studying epithelial cell polarity. Viral particles of VSV-infected epithelial cells bud from the basolateral membrane, which is in contact with the internal milieu and the blood supply.
J, Ilvesaro, K, Metsikkö, K, Väänänen, J, Tuukkanen   +3 more
openaire   +2 more sources