OSU53 Rescues Human OB-6 Osteoblastic Cells from Dexamethasone through Activating AMPK Signaling.
PLoS ONE, 2016 Excessive dexamethasone (Dex) application causes osteoblast cell death, which could lead to osteoporosis or osteonecrosis. AMP-activated protein kinase (AMPK) activation is shown to protect osteoblasts/osteoblastic cells from Dex.
Dawei Xu +8 more
doaj +2 more sources
Cord blood-derived macrophage-lineage cells rapidly stimulate osteoblastic maturation in mesenchymal stem cells in a glycoprotein-130 dependent manner. [PDF]
PLoS ONE, 2013 In bone, depletion of osteoclasts reduces bone formation in vivo, as does osteal macrophage depletion. How osteoclasts and macrophages promote the action of bone forming osteoblasts is, however, unclear.
Tania J Fernandes +8 more
doaj +4 more sources
Decorin Promotes Osteoblastic Differentiation of Human Periodontal Ligament Stem Cells
Molecules, 2022 The aim of this study is to clarify the biological functions of decorin (DCN) in the healing and regeneration of wounded periodontal tissue. We investigated the expression pattern of DCN during the healing of wounded periodontal tissue in rats by ...
Orie Adachi +13 more
doaj +2 more sources
Vinpocetine Attenuates the Osteoblastic Differentiation of Vascular Smooth Muscle Cells. [PDF]
PLoS ONE, 2016 Vascular calcification is an active process of osteoblastic differentiation of vascular smooth muscle cells; however, its definite mechanism remains unknown.
Yun-Yun Ma +8 more
doaj +2 more sources
The role of lysophosphatidylcholine acyltransferase 2 in osteoblastic differentiation of C2C12 cells
FEBS Open BioGlycerophospholipids, a primary component of cellular membranes, play important structural and functional roles in cells. In the remodelling pathway (Lands' cycle), the concerted actions of phospholipase As and lysophospholipid acyltransferases (LPLATs ...
Shirou Tabe +5 more
doaj +2 more sources
Vitamin D Effects on Osteoblastic Differentiation of Mesenchymal Stem Cells from Dental Tissues [PDF]
Stem Cells International, 2016 1α,25-Dihydroxyvitamin D3 (1,25(OH)2D3), the active metabolite of vitamin D (Vit D), increases intestinal absorption of calcium and phosphate, maintaining a correct balance of bone remodeling.
Francesca Posa +8 more
doaj +2 more sources
A Neuroprotective Bovine Colostrum Attenuates Apoptosis in Dexamethasone-Treated MC3T3-E1 Osteoblastic Cells. [PDF]
Int J Mol Sci, 2021 Glucocorticoid-induced osteoporosis (GIO) is one of the most common secondary forms of osteoporosis. GIO is partially due to the apoptosis of osteoblasts and osteocytes.
Martin-Aragon S +10 more
europepmc +2 more sources
Effects of rmBMP-7 on Osteoblastic Cells Grown on a Nanostructured Titanium Surface. [PDF]
Biomimetics (Basel), 2022 This study evaluates the effects of the availability of exogenous BMP-7 on osteoblastic cells’ differentiation on a nanotextured Ti surface obtained by chemical etching (Nano-Ti). The MC3T3-E1 and UMR-106 osteoblastic cell lines were cultured for 5
Zuardi LR +6 more
europepmc +3 more sources
BMC Cancer, 2017 Background Metastasis of breast cancer displays site-specificity towards bone. Recently, studies have emerged indicating that primary tumors may remotely influence creation of a pre-metastatic niche.
Karis Chin-Quee, Henry J. Donahue
doaj +1 more source
Cancer Reports, 2023 Background Osteoblastic skeletal metastasis is frequently observed in prostate cancer. An effective therapy has not been developed due to the unclear molecular mechanism.
Aya Sugyo +5 more
doaj +1 more source