Results 11 to 20 of about 4,458,897 (200)

OSU53 Rescues Human OB-6 Osteoblastic Cells from Dexamethasone through Activating AMPK Signaling.

PLoS ONE, 2016
Excessive dexamethasone (Dex) application causes osteoblast cell death, which could lead to osteoporosis or osteonecrosis. AMP-activated protein kinase (AMPK) activation is shown to protect osteoblasts/osteoblastic cells from Dex.
Dawei Xu, Wei Zhao, Xinhui Zhu, Jianbo Fan, Shengyu Cui, Yuyu Sun, Xiang Chen, Wei Liu, Zhi-Ming Cui   +8 more
doaj   +2 more sources

The role of lysophosphatidylcholine acyltransferase 2 in osteoblastic differentiation of C2C12 cells

FEBS Open Bio
Glycerophospholipids, a primary component of cellular membranes, play important structural and functional roles in cells. In the remodelling pathway (Lands' cycle), the concerted actions of phospholipase As and lysophospholipid acyltransferases (LPLATs ...
Shirou Tabe, Hisako Hikiji, Tomomi Hashidate‐Yoshida, Hideo Shindou, Takao Shimizu, Kazuhiro Tominaga   +5 more
doaj   +2 more sources

Vitamin D Effects on Osteoblastic Differentiation of Mesenchymal Stem Cells from Dental Tissues [PDF]

Stem Cells International, 2016
1α,25-Dihydroxyvitamin D3 (1,25(OH)2D3), the active metabolite of vitamin D (Vit D), increases intestinal absorption of calcium and phosphate, maintaining a correct balance of bone remodeling.
Francesca Posa, Adriana Di Benedetto, Graziana Colaianni, Elisabetta A. Cavalcanti-Adam, Giacomina Brunetti, Chiara Porro, Teresa Trotta, Maria Grano, Giorgio Mori   +8 more
doaj   +2 more sources

A Neuroprotective Bovine Colostrum Attenuates Apoptosis in Dexamethasone-Treated MC3T3-E1 Osteoblastic Cells. [PDF]

Int J Mol Sci, 2021
Glucocorticoid-induced osteoporosis (GIO) is one of the most common secondary forms of osteoporosis. GIO is partially due to the apoptosis of osteoblasts and osteocytes.
Martin-Aragon S, Bermejo-Bescós P, Benedí J, Raposo C, Marques F, Kydonaki EK, Gkiata P, Koutedakis Y, Ntina G, Carrillo AE, Amorim T.   +10 more
europepmc   +2 more sources

Limitations of bone formation in oral implantology: inhibition of osteoblast functions by gingival tissues [PDF]

, 2010
PhDClinical observation suggest that bone formation is influenced by the environmental niche where it takes place and specifically that soft connective tissues may inhibit the bone healing process.
Al-Masri, Maher
core   +4 more sources

Osteogenic Potential of Pre-Osteoblastic Cells on a Chitosan-graft-Polycaprolactone Copolymer. [PDF]

Materials (Basel), 2018
Georgopoulou A, Kaliva M, Vamvakaki M, Chatzinikolaidou M.   +3 more
europepmc   +2 more sources

Antagonizing exosomal miR-18a-5p derived from prostate cancer cells ameliorates metastasis-induced osteoblastic lesions by targeting Hist1h2bc and activating Wnt/β-catenin pathway

Genes and Diseases, 2023
More than 50% of prostate cancer (PCa) patients have bone metastasis with osteoblastic lesions. MiR-18a-5p is associated with the development and metastasis of PCa, but it remains unclear whether it is involved in osteoblastic lesions.
Fanchun Zeng, Chunrong Zhao, Rujie Wang, Lingyan Ren, Hao Qiu, Zhi Zou, Haibin Ding, Zhongyi Sun, Jianmei Li, Shiwu Dong   +9 more
doaj   +1 more source

Investigation of FGFR2-IIIC signaling via FGF-2 ligand for advancing GCT stromal cell differentiation. [PDF]

PLoS ONE, 2012
Giant cell tumor of bone (GCT) is an aggressive bone tumor consisting of multinucleated osteoclast-like giant cells and proliferating osteoblast-like stromal cells.
Shalini Singh, Mohini Singh, Isabella W Y Mak, Robert Turcotte, Michelle Ghert   +4 more
doaj   +1 more source

MDA-MET-conditioned-medium augments the chemoattractant-dependent migration of MDA-MET cells towards hFOB-conditioned medium and increases collagenase activity

BMC Cancer, 2017
Background Metastasis of breast cancer displays site-specificity towards bone. Recently, studies have emerged indicating that primary tumors may remotely influence creation of a pre-metastatic niche.
Karis Chin-Quee, Henry J. Donahue
doaj   +1 more source

Downregulation of miR-184 facilitates osseous differentiation in periodontal ligament stem cells by modulating nuclear factor I-C

Journal of Dental Sciences, 2021
Background/purpose: PDLSCs (periodontal ligament stem cells), derived from dental tissues, are candidate cells for regeneration of dental tissues. MiRNAs could regulate osteogenic differentiation and the transformation into osteoblasts.
Chunying Li, Guanglin Duan, Yaopu Feng
doaj   +1 more source