Results 21 to 30 of about 5,649,689 (153)

The role of prostate-specific antigen in the osteoblastic bone metastasis of prostate cancer: a literature review

open access: yesFrontiers in Oncology, 2023
Prostate cancer is the only human malignancy that generates predominantly osteoblastic bone metastases, and osteoblastic bone metastases account for more than 90% of osseous metastases of prostate cancer.
Xu Zhang, Peng Jiang, Chaojun Wang
doaj   +1 more source

Mesenchymal Differentiation and Organ Distribution of Established Human Stromal Cell Lines in NOD/SCID Mice [PDF]

open access: yes, 2001
Two human stromal cell lines were established previously from bone marrow-derived primary long-term cultures by immortalization using the SV40 large T antigen and cellular cloning. After irradiation, the fibroblast-like cell lines L87/4 and L88/5 support
Thalmeier, Karin   +6 more
core   +1 more source

Phenolic content of Sicilian virgin olive oils and their effect on MG-63 human osteoblastic cell proliferation

open access: yesGrasas y Aceites, 2014
The aim of this study was, first, to investigate the influence of olive variety and elevation of orchards on the phenolic compound content of Sicilian virgin olive oils (VOOs) and, second, to investigate the effects of VOO phenolic extracts on osteoblast
O. García-Martínez   +4 more
doaj   +1 more source

Proposal of a Novel Natural Biomaterial, the Scleral Ossicle, for the Development of Vascularized Bone Tissue In Vitro

open access: yesBiomedicines, 2017
Recovering of significant skeletal defects could be partially abortive due to the perturbations that affect the regenerative process when defects reach a critical size, thus resulting in a non-healed bone.
Marta Checchi   +6 more
doaj   +1 more source

Single-Cell Transcriptomics Reveals the Complexity of the Tumor Microenvironment of Treatment-Naive Osteosarcoma

open access: yesFrontiers in Oncology, 2021
Osteosarcoma (OS), which occurs most commonly in adolescents, is associated with a high degree of malignancy and poor prognosis. In order to develop an accurate treatment for OS, a deeper understanding of its complex tumor microenvironment (TME) is ...
Yun Liu   +47 more
doaj   +1 more source

Involvement of microRNAs in regulation of osteoblastic differentiation in mouse induced pluripotent stem cells. [PDF]

open access: yesPLoS ONE, 2012
UNLABELLED: BACKGOROUND: MicroRNAs (miRNAs), which regulate biological processes by annealing to the 3'-untranslated region (3'-UTR) of mRNAs to reduce protein synthesis, have been the subject of recent attention as a key regulatory factor in cell ...
Hideharu Okamoto   +5 more
doaj   +1 more source

Zinc Sulfate Stimulates Osteogenic Phenotypes in Periosteum-Derived Cells and Co-Cultures of Periosteum-Derived Cells and THP-1 Cells

open access: yesLife, 2021
Coupling between osteoblast-mediated bone formation and osteoclast-mediated bone resorption maintains both mechanical integrity and mineral homeostasis. Zinc is required for the formation, mineralization, growth, and maintenance of bones. We examined the
Jin-Ho Park   +7 more
doaj   +1 more source

IL-6 stimulation enhances expressions of osteoblastic factors and cell proliferation factors in ligamentum flavum cells.

open access: yes, 2022
(A) Effect of IL-6 on expressions of osteoblastic factors BMP2, ALP and RUNX2. Gene expressions were determined via qRT-PCR in ligamentum flavum cells with (IL-6) or without (Ctrl) IL-6 stimulation; (B) Effect of IL-6 on expressions of osteoblastic ...
Zhongqiang Chen (191240)   +3 more
core   +1 more source

Different titanium surfaces influence in vitro the biological behavior of SaOS-2 human osteoblast-like cells. [PDF]

open access: yes, 2009
Osseointegrated dental implants have been successfully used over the past several years, allowing functional replacement of missing teeth. Surface properties of titanium dental implants seem to affect bone cell response.
Capece, Gabriele
core   +1 more source

Platelet-Derived Growth Factor Stimulates Osteoprotegerin Production in Osteoblastic Cells

open access: yes, 2008
Osteoprotegerin (OPG) is a major regulator of osteoclastogenesis, bone resorption and vascular calcification. OPG is produced by various cell types including mesenchymally derived cells, in particular, osteoblastic cells.
Williams, John H. H.   +3 more
core   +2 more sources

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