Results 41 to 50 of about 4,458,897 (200)

The Effect of Zoledronic Acid on BSP Expression and Methylation during Osteoblastic Differentiation of Mesenchymal Stem Cells [PDF]

پیاورد سلامت, 2011
Background and Aim: Bone sialoprotein (BSP) is a specific marker of osteoblastic differentiation. In this research, the effect of Zoledronic Acid on BSP expression and methylation status during osteoblastic differentiation of mesenchymal stem cells (MSCs)
M Mahmodi Niya Meymand, S Kaviyany, M Soleymani, Y Mortazavi, M Nowrozi Niya, M Farsh Dusty Hagh   +5 more
doaj   +2 more sources

Thyroid-Stimulating Hormone Favors Runx2-Mediated Matrix Mineralization in HOS and SaOS2 Cells: An In Vitro and In Silico Approach

Molecules, 2022
Osteoporosis is a skeletal disease that is both systemic and silent characterized by an unbalanced activity of bone remodeling leading to bone loss.
Ramajayam Govindan, Mohamed El-Sherbiny, Khalid Mohamed Morsy Ibraheem, Srinivasan Narasimhan, Mohamed EL-Dosoky Mohamed Salama, Fazil Ahmad, Selvaraj Jayaraman, Vishnu Priya Veeraraghavan, Srinivasan Vengadassalapathy, Surapaneni Krishna Mohan, Vidhya Rekha Umapathy, Gayathri Rengasamy, Shazia Fathima Jaffer Hussain, Maheshkumar Poomarimuthu, Senthilkumar Kalimuthu   +14 more
doaj   +1 more source

Kynurenine suppresses osteoblastic cell energetics in vitro and osteoblast numbers in vivo [PDF]

Experimental Gerontology, 2020
Aging is a progressive process associated with declining tissue function over time. Kynurenine, an oxidized metabolite of the essential amino acid tryptophan that increases in abundance with age, drives cellular processes of aging and dysfunction in many tissues, and recent work has focused on understanding the pathways involved in the harmful effects ...
Jessica L, Pierce, Rachel L, Roberts, Kanglun, Yu, Riley K, Kendall, Helen, Kaiser, Colleen, Davis, Maribeth H, Johnson, William D, Hill, Carlos M, Isales, Wendy B, Bollag, Mark W, Hamrick, Meghan E, McGee-Lawrence   +11 more
openaire   +2 more sources

RRBP1 depletion of bone metastatic cancer cells contributes to enhanced expression of the osteoblastic phenotype

Frontiers in Oncology, 2022
Bone metastatic cancer-secreted extracellular factors are capable of modifying the bone microenvironment through interacting with bone cells, including osteoblasts.
Rui Chen, Yue Wang, Yang Xu, Yaohui He, Qing Li, Chun Xia, Bing Zhang   +6 more
doaj   +1 more source

Transcriptional Profiling of Bone Marrow Stromal Cells in Response to Porphyromonas gingivalis Secreted Products [PDF]

, 2012
Periodontitis is an infectious inflammatory disease that destroys the tooth-supporting (periodontal) tissues. Porphyromonas gingivalis is an oral pathogen highly implicated in the pathogenesis of this disease.
Reddi, D, Belibasakis, GN, Belibasakis, Georgios N, Durga Reddi (140451), Georgios N Belibasakis, Reddi, Durga, Georgios N. Belibasakis (140456), Reddi Durga, Durga Reddi, Belibasakis Georgios N.   +9 more
core   +2 more sources

Identification of a clinical signature predictive of differentiation fate of human bone marrow stromal cells

Stem Cell Research & Therapy, 2021
Background Transplantation of human bone marrow stromal cells (hBMSCs) is a promising therapy for bone regeneration due to their ability to differentiate into bone forming osteoblastic cells.
Justyna Magdalena Kowal, Sören Möller, Dalia Ali, Florence Figeac, Torben Barington, Hagen Schmal, Moustapha Kassem   +6 more
doaj   +1 more source

The role of osteoblast cells in the pathogenesis of unicameral bone cysts

, 2012
PurposeThe pathogenesis of unicameral bone cysts (UBCs) remains largely unknown. Osteoclasts have been implicated, but the role of osteoblastic cells has, to date, not been explored.
Tayton, Edward R, Fowler, Darren J., Edward D. Gent, Richard O. C. Oreffo, Smith, James O., Oreffo, Richard O.C., Caroline J. Edwards, Edward R. Tayton, James O. Smith, Aarvold, Alexander, Darren J. Fowler, Gent, Edward D., Edwards, Caroline J., Alexander Aarvold   +13 more
core   +1 more source

Overexpression of hsa-miR-125b during osteoblastic differentiation does not influence levels of Runx2, osteopontin, and ALPL gene expression

Brazilian Journal of Medical and Biological Research, 2013
Multipotent mesenchymal stromal cells (MSCs) were first isolated from bone marrow and then from various adult tissues including placenta, cord blood, deciduous teeth, and amniotic fluid.
M.T. Pinto, L.D.F. Nicolete, E.S. Rodrigues, P.V.B. Palma, M.D. Orellana, S. Kashima, D.T. Covas   +6 more
doaj   +1 more source

lncRNA TUG1 promotes proliferation and differentiation of osteoblasts by regulating the miR-545-3p/CNR2 axis [PDF]

Brazilian Journal of Medical and Biological Research, 2020
Osteoblast differentiation is an effective way to promote bone formation. Long non-coding RNA taurine upregulated 1 (TUG1) has been identified as a crucial modulator of multiple biological processes. This study was designed to investigate the function of
Ruizheng Hao, Bin Wang, Hui Wang, Yongxin Huo, Yang Lu   +4 more
doaj   +1 more source

Cell Death in Chondrocytes, Osteoblasts, and Osteocytes [PDF]

International Journal of Molecular Sciences, 2016
Cell death in skeletal component cells, including chondrocytes, osteoblasts, and osteocytes, plays roles in skeletal development, maintenance, and repair as well as in the pathogenesis of osteoarthritis and osteoporosis. Chondrocyte proliferation, differentiation, and apoptosis are important steps for endochondral ossification.
openaire   +2 more sources