Results 51 to 60 of about 4,458,897 (200)

The importance of cellular and exosomal miRNAs in mesenchymal stem cell osteoblastic differentiation

open access: yesScientific Reports, 2021
The differentiation of osteoblasts is under complex regulation that includes autocrine and paracrine signaling from MSCs. Exosomes are important components of the MSC secretome and their cargo contains numerous miRNAs.
Sajjad Shirazi   +5 more
doaj   +1 more source

Effects of (+)-Catechin on the Function of Osteoblastic Cells.

open access: yesBiological and Pharmaceutical Bulletin, 2003
Tumor necrosis factor-alpha (TNF-alpha) and interleukin-6 (IL-6) are candidate cytokines which are produced by osteoblastic linage cells and promote osteoblast apoptosis, osteoclastogenesis and bone resorption. Here, we examined the effect of (+)-catechin, one of the most common grape flavonols, on osteoblastic MC3T3-E1 cells.
Choi, Eun-Mi, Hwang, Jae-Kwan
openaire   +3 more sources

Prostate Cancer Cells Promote Osteoblastic Bone Metastases through Wnts

open access: yes, 2005
Prostate cancer produces painful osteoblastic bone metastases. Although prostate cancer cells produce numerous osteogenic factors, to date, none have been shown to mediate osteoblastic bone metastases in an in vivo model of prostate cancer.
Christopher L. Hall   +4 more
core   +1 more source

Single-cell resolution of MET- and EMT-like programs in osteoblasts during zebrafish fin regeneration

open access: yesiScience, 2022
Summary: Zebrafish regenerate fin rays following amputation through epimorphic regeneration, a process that has been proposed to involve the epithelial-to-mesenchymal transition (EMT).
W. Joyce Tang   +4 more
doaj   +1 more source

Lithograph-moulded poly-L-co-D,L lactide porous membranes for osteoblastic culture [PDF]

open access: yesMaterials Research, 2013
Pore size, shape, wall morphology, porosity, and interconnectivity are important characteristics of the scaffolds. Lithography is a manufacturing technique that allows the production of tridimensional scaffolds with a controllable and reproducible inner ...
Andre D. Messias   +4 more
doaj  

Osteoblast‐derived extracellular vesicles exert osteoblastic and tumor‐suppressive functions via SERPINA3 and LCN2 in prostate cancer

open access: yesMolecular Oncology, 2023
Clinically, the osteolytic phenotype is rare in prostate cancer (PCa), and the prognosis is generally worse than that of the osteoblastic phenotype. Osteoblastic prostate cancer (BPCa) is a major type of bone metastasis.
Kagenori Ito   +13 more
doaj   +1 more source

Fibroblast growth factor 2 supports osteoblastic niche cells during hematopoietic homeostasis recovery after bone marrow suppression

open access: yesCell Communication and Signaling, 2017
Background Hematopoietic stem cell (HSC) maintenance requires a specific microenvironment. HSC niches can be activated by tissue damaging chemotherapeutic drugs and various cell signaling molecules such as SDF-1 and FGF, which might also result in bone ...
Kyung-Ae Yoon   +4 more
doaj   +1 more source

JAK2 Inhibition by Fedratinib Reduces Osteoblast Differentiation and Mineralisation of Human Mesenchymal Stem Cells

open access: yesMolecules, 2021
Several signalling pathways, including the JAK/STAT signalling pathway, have been identified to regulate the differentiation of human bone marrow skeletal (mesenchymal) stem cells (hBMSCs) into bone-forming osteoblasts.
Nihal AlMuraikhi   +5 more
doaj   +1 more source

Primary osteoblasts, osteoblast precursor cells or osteoblast‐like cell lines: Which human cell types are (most) suitable for characterizing 45S5‐bioactive glass? [PDF]

open access: yesJournal of Biomedical Materials Research Part A, 2019
AbstractThe question how bioactive glasses (BGs) influence the viability and osteogenic differentiation of human osteogenic cells has already been addressed by several studies. However, a literature review revealed great differences in the type of cells used for these experiments.
Sebastian Wilkesmann   +6 more
openaire   +3 more sources

Manifestation of osteoblastic phenotypes in the sarcomatous component of epithelial carcinoma and sarcomatoid carcinoma

open access: yesTumor Biology, 2017
Epithelial carcinomas occasionally have sarcomatous components that consist primarily of spindle and cuboidal cells, which often resemble osteoblasts. Sarcomatoid carcinomas consist of similar cells. Recent studies have characterized these phenomena as a
Yasutoshi Takashima   +7 more
doaj   +1 more source

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