Strontium potently inhibits mineralisation in bone-forming primary rat osteoblast cultures and reduces numbers of osteoclasts in mouse marrow cultures [PDF]
, 2014 D. P. Wornham +3 more
openalex +1 more source
Artificial Intelligence for Bone: Theory, Methods, and Applications
Advanced Intelligent Discovery, EarlyView.Advances in artificial intelligence (AI) offer the potential to improve bone research. The current review explores the contributions of AI to pathological study, biomarker discovery, drug design, and clinical diagnosis and prognosis of bone diseases. We envision that AI‐driven methodologies will enable identifying novel targets for drugs discovery. The
Dongfeng Yuan +3 more
wiley +1 more source
Pharmacological inhibition of RAS pathway alleviates spine deformity in a mouse model of neurofibromatosis type 1. [PDF]
Bone ResKovaci F +7 more
europepmc +1 more source
Helical Rosette Nanotubes: Topographical and Chemical Roles in Osteoblast Attachment
, 2006 Ai Lin Chun +2 more
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An in vivo assay for osteoclast activity using mouse calvaria
Animal Models and Experimental Medicine, EarlyView.This study describes a novel method for measuring osteoclast‐mediated bone resorption in vivo using a mouse model. Localized injection of RANKL in a basement membrane matrix above the cranium induced osteoclast‐mediated bone resorption. Utilizing micro‐computed tomography and a semiautomated three‐dimensional analysis program, osteoclast resorption pit
Christopher Grieg +2 more
wiley +1 more source
Cytocompatibility and Microbiological Effects of Ti6Al4V Particles Generated During Implantoplasty on Human Fibroblasts, Osteoblasts, and Multispecies Oral Biofilm. [PDF]
Materials (Basel)Vegas-Bustamante E +8 more
europepmc +1 more source
Comprehending the Membrane Properties for Emulation in Organs‐on‐a‐Chip
Advanced NanoBiomed Research, EarlyView.The advent of organ‐on‐chip models allows closer emulation of in vivo conditions, leading to effective, less costly, and specific drugs. Although a number of membrane‐based on‐chip models exist, better emulating functional models need to be devised for organ simulations.
Tanmayee Makarand Sathe +1 more
wiley +1 more source
The Crosstalk Between B Cells and the Skeletal System During Development, Aging, and in Pathological Conditions. [PDF]
Curr Osteoporos RepTerhaar H +9 more
europepmc +1 more source
Regulatory Mechanism of Osteoblast Differentiation by Recombinant Amelogenin
, 2009 Mitsuhiro Matsuzawa
openalex +1 more source
3D Hydrogel Cell Cultures and Their Biomedical Applications
Advanced NanoBiomed Research, EarlyView.The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai +7 more
wiley +1 more source