Spatially resolved osteoblast-traced transcriptomics uncovers TGF-β as a combination target with sclerostin in osteoporosis. [PDF]
Choi A +16 more
europepmc +1 more source
Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang +13 more
wiley +1 more source
Intraosseous therapy: harnessing the potential of tissue regeneration and repair. [PDF]
Artamonov MY, Minenko IA.
europepmc +1 more source
Abstract Background Autogenous particulate dentin has emerged as one of the promising biocompatible alternatives to traditional bone graft materials in alveolar ridge augmentation. Although its clinical success is documented, comprehensive studies combining histological and radiographic evaluations remain limited. This case report addresses this gap by
Kosuke Kashiwagi +4 more
wiley +1 more source
Lipid nanoparticles for nucleic acid delivery to osteoblasts and osteoblast-lineage cells: A systematic review. [PDF]
Murphy AI, Vargas C, Pomerantz JH.
europepmc +1 more source
Subperiosteal peri‐implant augmented layer to correct bone dehiscence at immediate implant placement
Abstract Background The purpose of the present case report is to describe the potential of the subperiosteal peri‐implant augmented layer (SPAL) technique in peri‐implant bone dehiscence (PIBD) correction at immediate implant placement (IIP). Methods This case report describes the application of the SPAL technique in two patients undergoing IIP at ...
Tommaso Grenzi +3 more
wiley +1 more source
Piezo1 ion channel: a core target for mechanotransduction in orthodontic alveolar bone remodeling. [PDF]
Yan Y +7 more
europepmc +1 more source
A nanoporous carbon‐coated FeCoNiCrZn multi‐element alloy on carbon cloth (FeCoNiCrZn‐C@CC) is fabricated by ultrafast pulsed laser irradiation. It has excellent OER performance, achieving an overpotential of only 233 mV at 10 mA cm−2 and remarkable stability for 94 h at 250 mA cm−2, which is due to multiple factors.
Yu Liang +12 more
wiley +1 more source
Region- and Compartment-Specific Elevation of Bone Mass in Mice Following Tsc1 Deletion in 8-kb Dmp1-Cre-Expressing Cells. [PDF]
Ghassib I +13 more
europepmc +1 more source
Discontinuing Long‐Term Denosumab in Treating Fragile Bone: Why, for Whom, and How?
Discontinuation of denosumab (Dmab) may be necessary due to adverse events or an unfavorable long‐term risk–benefit profile. However, accumulating evidence demonstrates pronounced rebound phenomena after withdrawal, most notably a marked increase in multiple vertebral fractures, and, in some reports, elevated mortality.
Ko‐Hsiu Lu +5 more
wiley +1 more source

