ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley +1 more source
Influence of Ti-6Al-4V Scaffold Architecture on Early Cellular Responses Relevant to Bone Regeneration. [PDF]
Armakolas A +8 more
europepmc +1 more source
Senotherapeutics for Knee Osteoarthritis
ABSTRACT Osteoarthritis (OA) is a chronic disease that imposes a significant economic burden and deteriorates quality of life. Nevertheless, current therapeutic options for OA are limited to symptomatic remedies. As such, there is a high interest in novel methods for treating or preventing OA.
Ezgi Duman +6 more
wiley +1 more source
mTOR signalling mediates the spinal osteoblast pathotype at the curve apex in adolescent idiopathic scoliosis. [PDF]
Northall EH +7 more
europepmc +1 more source
Recent Advances in Cryogel Applications for Musculoskeletal Regeneration
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim +4 more
wiley +1 more source
Role of the Antioxidant Lycopene in Bone Health: Emphasis on the RANKL/RANK/OPG Signaling Pathway. [PDF]
Esmaili H +3 more
europepmc +1 more source
Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli +5 more
wiley +1 more source
Research Progress in Smart Hydrogel-Based Colloidal Systems for Osteoporosis Treatment. [PDF]
Wang Z, Zhang J, Zhang B, Jiang Y.
europepmc +1 more source
The Audiologic and Otolaryngologic Phenotype in WHIM Syndrome
Abstract Objective WHIM syndrome (warts, hypogammaglobulinemia, infections, and myelokathexis syndrome) is an ultra‐rare primary immunodeficiency disease caused by autosomal dominant hyperfunctional mutations in the chemokine receptor CXCR4. Otolaryngologists are frequently consulted to evaluate WHIM patients because of recurrent acute ear and sinus ...
Christopher K. Zalewski +7 more
wiley +1 more source
Inherent tissue homeostasis of the juvenile metaphysis provides a foundation for osteosarcoma development. [PDF]
Saito M +16 more
europepmc +1 more source

