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mTOR signalling mediates the spinal osteoblast pathotype at the curve apex in adolescent idiopathic scoliosis

open access: yes
Northall EH   +7 more
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The migration of osteoblasts

Cell and Tissue Research, 1977
The endocranial matrix surfaces of parietal bones of 2-week old Albino Wistar rats were partly denuded of osteoblasts and then cultured for various periods up to 24 h, in control or PTE-enriched medium. They were examined by scanning electron microscopy and evidence for cell locomotion was found.
S J, Jones, A, Boyde
openaire   +2 more sources

Regulation of Osteoblast Differentiation by Slit2 in Osteoblastic Cells

Cells Tissues Organs, 2008
<i>Background/Aims:</i> There is an urgent need to identify the molecular factors involved in osteoblast proliferation and differentiation in order to improve bone formation and treat bone disease. Recent studies demonstrate that many ‘axon guidance’ molecules play important roles in the development and remodeling of bone through their ...
Hongli, Sun   +3 more
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Regulation of Osteoblast Activity and the Osteoblast-Osteocyte Transformation

1982
According to currently held concepts of bone formation (Table 1), osteoblasts develop from mitotically competent marrow stromal cells by a process of non-mitotic differentiation (modulation) (1,2). Osteoblasts are attracted to the bone surfaces, and are activated to elaborate lamellae of collagen-rich organic matrix (osteoid) which is subsequently ...
W A, Peck, L, Rifas
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Osteoclast–osteoblast communication

Archives of Biochemistry and Biophysics, 2008
Cells in osteoclast and osteoblast lineages communicate with each other through cell-cell contact, diffusible paracrine factors and cell-bone matrix interaction. Osteoclast-osteoblast communication occurs in a basic multicellular unit (BMU) at the initiation, transition and termination phases of bone remodeling.
Koichi, Matsuo, Naoko, Irie
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Osteoblasts: yes, they can

Blood, 2008
In this issue of Blood , Mayak and Wagers report on a new method to isolate putative osteoblastic cells that can regulate hematopoietic stem cell proliferation and function. The cellular and extracellular matrix components that support and regulate hematopoietic stem cells (HSCs) form niches ...
Daniel, Lucas, Paul S, Frenette
openaire   +2 more sources

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