Results 71 to 80 of about 31,358 (262)

Gelatin-based biomaterials as a delivery strategy for osteosarcoma treatment

open access: yesFrontiers in Pharmacology
Osteosarcoma is the most common primary malignant bone tumor. Although surgery and chemoradiotherapy have made some progress in the treatment of osteosarcoma.
Qifan Yang   +3 more
doaj   +1 more source

Enabling Real‐Time, Non‐Ionizing 3D Imaging of Implantable Magnetic Cements Using Magnetic Particle Imaging

open access: yesAdvanced Materials Interfaces, EarlyView.
This study reports the first implantable resin cement capable of orientation‐sensitive Magnetic Particle Imaging (MPI). By coating the cement with an ultrathin iron film, the authors achieve a strong, angle‐dependent MPI signal that enables non‐ionizing, real‐time tracking of both implant position and orientation, opening new possibilities for safe ...
Gabriel C. Pinto   +10 more
wiley   +1 more source

Fabrication, Properties, and Applications of Scaffolds for Bone Tissue Regeneration

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores cutting‐edge biomaterials and fabrication techniques for scaffolds in bone tissue regeneration. It conducts a critical comparison of various strategies, meticulously analyzes the key contradictions in the field, and outlines an integrated development path spanning from biomaterial selection to clinical application, while ...
Shangsi Chen, Min Wang
wiley   +1 more source

CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro

open access: yesBone & Joint Research
Aims: To investigate the role of CXCR4 in response to teriparatide (TPTD) treatment in osteoblasts and osteoclasts. Methods: Primary murine and human osteoblasts and osteoclasts, MC3T3 cell lines, and hMSC-TERT4 cell lines were treated with TPTD and/or
Beatriz Larraz-Prieto   +9 more
doaj   +1 more source

Evaluation of Light-Emitting Diode (LED-660 Nm) Application over Primary Osteoblast-Like Cells on Titanium Surfaces: An In Vitro Study [PDF]

open access: gold, 2011
Abdülkadir Burak Çankaya   +6 more
openalex   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

open access: yesAdvanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias   +4 more
wiley   +1 more source

A Three-Dimensional Dense Collagen Hydrogel to Model Cancer Cell/Osteoblast Interactions

open access: yesJournal of Functional Biomaterials, 2018
No curative treatment options exist once breast cancer metastasizes to bone. This is due, in part, to an incomplete understanding of how osteolytic cancers interact with bone.
Mark James-Bhasin   +2 more
doaj   +1 more source

Engineered Microfluidic Organoid Systems: New Paradigms for Menopause Mechanism Research and Personalized Medicine

open access: yesAdvanced Materials Technologies, EarlyView.
This review explores the integration of microfluidic technology with organoid systems as an innovative platform for studying menopausea complex multi‐organ condition. By enabling precise simulation of inter‐organ communication and hormone responses, microfluidic organoids offer a physiologically relevant model for investigating menopausal syndrome and ...
Qianyi Zhang   +4 more
wiley   +1 more source

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

open access: yesAdvanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang   +7 more
wiley   +1 more source

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