Results 91 to 100 of about 197,419 (304)

Histological and immunohistochemical evaluation of mandibular bone tissue regeneration [PDF]

, 2018
The purpose of the study was to perform an immunohistochemical and histological evaluation of samples taken from different bone regeneration procedures in atrophic human mandible.
Brauner, E, Cimpian, A M, CIOBANU, GALINA, De Angelis, F, Di Carlo, S, Papi, P, Pompa, G, Rosella, D, Saptefrati, L   +8 more
core   +1 more source

Opinion: Gavage Administration of MXene as a Route‐Specific Alternative to Intravenous Injection into the Bloodstream of Laboratory Animals for Reducing Systemic Nanotoxicity Risks in Immunosuppression and Post‐Transplantation Models with Bile Acid Modification

Advanced Healthcare Materials, EarlyView.
Recent studies reported immunosuppressive properties of specific MXene nanomaterials. Their intravenous injection into the bloodstream of laboratory animals has been a common delivery method to suppress systemic inflammation and prevent transplant rejection.
Alireza Rafieerad, M. Akif Rahman, Ahmad Amiri   +2 more
wiley   +1 more source

The Roles of Fibrinolytic Factors in Bone Destruction Caused by Inflammation

Cells
Chronic inflammatory diseases, such as rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, Crohn’s disease, periodontitis, and carcinoma metastasis frequently result in bone destruction.
Yosuke Kanno
doaj   +1 more source

Recapitulating Endochondral Ossification for Bone Repair: From Development to Engineering Strategy

Advanced Healthcare Materials, EarlyView.
This review summarizes the developmental basis of endochondral ossification (ECO) and its applications in bone tissue engineering (BTE). It first outlines the key biological processes and signaling pathways underlying ECO, then discusses biomaterial‐based engineering strategies derived from these principles, and finally highlights future directions for
Yiqi Su, Zihao He, Qianqian Chen, Long Chen, Caiyi Wei, Zijin Zhou, Jianhao Lin, Hui Li, Dan Xing   +8 more
wiley   +1 more source

Alterations in the self-renewal and differentiation ability of bone marrow mesenchymal stem cells in a mouse model of rheumatoid arthritis [PDF]

, 2010
Introduction: Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease primarily involving the synovium. Evidence in recent years has suggested that the bone marrow (BM) may be involved, and may even be the initiating site of the disease ...
Bellantuono, I., Coulton, L., Croucher, P.I., Gambardella, A., Hughes, D., Kottam, L., Mohanty, S.T., Nicklin, M.J., Wilson, A.G.   +8 more
core   +3 more sources

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source

Osteoblast-derived CCN1 : A paracrine regulator of osteoclastogenesis?

, 2011
Peer ...
Aspden, R. M., Crockett, J. C., Schuetze, N., Wang, W.   +3 more
core   +1 more source

Osteoclast differentiation from human blood precursors on biomimetic calcium-phosphate substrates [PDF]

, 2017
The design of synthetic bone grafts to foster bone formation is a challenge in regenerative medicine. Understanding the interaction of bone substitutes with osteoclasts is essential, since osteoclasts not only drive a timely resorption of the biomaterial,
Avnet, Sofia, Baldini, Nicola, Ciapetti, Gabriela, Díez Escudero, Anna, Ginebra Molins, Maria Pau, Martini, Desirée, Montufar Jiménez, Edgar Benjamin, Pompo, Gemma di   +7 more
core   +2 more sources

Mesoporous Silica Nanoparticles in Biomedicine: Advances and Prospects

Advanced Materials, EarlyView.
Mesoporous silica nanoparticles offer unique properties like high surface area, tunable pores, and functionalization. They excel in drug delivery, tissue engineering, and stimuli‐responsive therapies, enabling targeted and controlled treatments. With roles in cancer therapy and diagnostics, their clinical translation requires addressing challenges in ...
Miguel Manzano, María Vallet‐Regí
wiley   +1 more source

Gelatin-based biomaterials as a delivery strategy for osteosarcoma treatment

Frontiers in Pharmacology
Osteosarcoma is the most common primary malignant bone tumor. Although surgery and chemoradiotherapy have made some progress in the treatment of osteosarcoma.
Qifan Yang, Xingpeng Chen, Jing Liu, Yeteng He   +3 more
doaj   +1 more source