Results 91 to 100 of about 136,319 (308)

ZDHHC9‐Mediated Palmitoylation of ACSL4 Drives Ferroptosis in Diabetes Mellitus–Induced Erectile Dysfunction

open access: yesAdvanced Science, EarlyView.
ABSTRACT Diabetes mellitus‐induced erectile dysfunction (DMED) is a highly prevalent complication among diabetic patients; however, its underlying pathogenic mechanisms remain incompletely understood. Metabolic disorder is a hallmark of diabetes, yet its precise contribution to DMED progression is not well defined.
Wanyang Guo   +14 more
wiley   +1 more source

Multi‐Enzyme Mimetic Molybdenum Nitride Nanozymes Reshape Subgingival Microenvironment for Synergistic Periodontitis Therapy via ROS Regulation and Microbiome Remodeling

open access: yesAdvanced Science, EarlyView.
ABSTRACT Periodontitis, a chronic inflammatory disease initiated and sustained by plaque microorganisms and host immune response, remains an intractable oral disease and a leading cause of tooth loss worldwide. Traditional mechanical debridement and adjunctive antibiotic or antiseptic therapy often shows limited efficacy due to the complex anatomical ...
Weiyu Zhang   +12 more
wiley   +1 more source

In Vitro Differentiation of Preosteoblast-Like Cells, MC3T3-E1, to Adipocytes Is Enhanced by 1,25(OH)2 Vitamin D3

open access: yesFrontiers in Endocrinology, 2017
Osteoblasts and adipocytes originate from common mesenchymal progenitor cells and are controlled by specific transcription factors. While 1,25-dihydroxyvitamin D3 (vitamin D) is known to be an important factor for osteoblast differentiation, there are ...
Elisha Pendleton, Nalini Chandar
doaj   +1 more source

Lipoic Acid‐Intervened Decellularized Stem Cell Spheroid‐Based Injectable Granular Gel for Diabetic Tissue Regeneration

open access: yesAdvanced Science, EarlyView.
ABSTRACT Advancements in tissue engineering have revolutionized therapeutic paradigms for diabetic tissue defects; however, the lack of applicable scaffold containing various bioactive substance aggregates remained a critical bottleneck hindering satisfactory repair effect.
Tao Wang   +8 more
wiley   +1 more source

Different titanium surfaces influence in vitro the biological behavior of SaOS-2 human osteoblast-like cells.

open access: yes, 2009
Osseointegrated dental implants have been successfully used over the past several years, allowing functional replacement of missing teeth. Surface properties of titanium dental implants seem to affect bone cell response.
Capece, Gabriele
core  

Vesicular trafficking in osteoblasts [PDF]

open access: yes, 2001
Secretion of bone matrix proteins is highly directional. Osteoblasts secrete newly synthesised bone matrix proteins towards the bone surface and away from neighbouring capillaries.
Prele, Cecilia M. A.
core  

Osteoblasts of calvaria induce higher numbers of osteoclasts than osteoblasts from long bone

open access: yes, 2016
Several studies have demonstrated the existence of functional differences between osteoclasts harbored in different bones. The mechanisms involved in the occurrence of such a heterogeneity are not yet understood.
Schoenmaker, T.   +12 more
core   +1 more source

The role of osteoblasts in bone metastasis [PDF]

open access: yes, 2016
The primary role of osteoblasts is to lay down new bone during skeletal development and remodelling. Throughout this process osteoblasts directly interact with other cell types within bone, including osteocytes and haematopoietic stem cells. Osteoblastic
Penelope D Ottewell   +2 more
core   +1 more source

Metabolic differences between RTS and FC osteoblasts.

open access: yes, 2021
(A-E) Enzyme activity of complexes I and III (A), complex II (B), complexes II and III (C), complex IV (D), and citrate synthase (E) show no significant difference between RTS and FC osteoblasts, leaving complex I as the only component of the electron ...
Linchao Lu (11886284)   +28 more
core   +1 more source

Free Fatty Acids in Bone Pathophysiology of Rheumatic Diseases

open access: yesFrontiers in Immunology, 2019
Obesity—in which free fatty acid (FFA) levels are chronically elevated—is a known risk factor for different rheumatic diseases, and obese patients are more likely to develop osteoarthritis (OA) also in non-weight-bearing joints.
Klaus W. Frommer   +17 more
doaj   +1 more source

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