Results 101 to 110 of about 136,319 (308)

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Metabolic differences between RTS and FC osteoblasts demonstrate the role of OXPHOS in increasing ATP production in RTS osteoblasts.

open access: yes, 2021
(A) Enzyme activity of complex I is increased in RTS osteoblasts. n = 3 biological replicates. (B) Seahorse assays indicate increased oxygen consumption rate, a measure of OXPHOS, in RTS osteoblasts. n = 3 biological replicates.
Linchao Lu (11886284)   +28 more
core   +1 more source

Cell Biological and Antibacterial Evaluation of a New Approach to Zirconia Implant Surfaces Modified with MTA

open access: yesBiomimetics
Peri-implantitis continues to be one of the major reasons for implant failure. We propose a new approach to the incorporation of MTA into zirconia implant surfaces with Nd:YAG laser and investigate the biological and the microbiological responses of peri-
Beatriz Ferreira Fernandes   +8 more
doaj   +1 more source

Senolytic Therapy as a Preventive Strategy for Spine Degeneration and Pain

open access: yesAdvanced Science, EarlyView.
Cellular senescence promotes inflammation, tissue degeneration, and chronic back pain. In sparc‐null mice, early oral administration of the senolytic agents o‐vanillin and RG‐7112 reduced senescent cell burden and pro‐inflammatory SASP signaling across intervertebral discs, endplates, vertebral bone, and spinal cord.
Saber Ghazizadeh   +7 more
wiley   +1 more source

Effects of hyperbaric oxygen on proliferation and differentiation of osteoblasts derived from human alveolar bone

open access: yes, 2007
In view of the controversy of the clinical use of hyperbaric oxygen (HBO) treatment to stimulate fracture healing and bone regeneration, we have analysed the effects of daily exposure to HBO on the proliferation and differentiation of human osteoblasts ...
Malda, Jos   +3 more
core   +1 more source

Self-assembling peptide-enriched electrospun polycaprolactone scaffolds promote the h-osteoblast adhesion and modulate differentiation-associated gene expression [PDF]

open access: yes, 2012
Electrospun polycaprolactone (PCL) is able to support the adhesion and growth of h-osteoblasts and to delay their degradation rate to a greater extent with respect to other polyesters. The drawbacks linked to its employment in regenerative medicine arise
V. Samouillan   +23 more
core   +1 more source

The Roles of Fibrinolytic Factors in Bone Destruction Caused by Inflammation

open access: yesCells
Chronic inflammatory diseases, such as rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, Crohn’s disease, periodontitis, and carcinoma metastasis frequently result in bone destruction.
Yosuke Kanno
doaj   +1 more source

The Enkephalinergic Osteoblast [PDF]

open access: yesJournal of Bone and Mineral Research, 1998
H, Rosen, A, Krichevsky, Z, Bar-Shavit
openaire   +2 more sources

Osteoblasts and The Hematopoietic Microenvironment

open access: yesHematology, 1999
Cells of the bone marrow are chiefly dedicated to two processes; the production of blood, and the production of bone that houses the hematopoietic organ. The majority of our understanding of these processes comes from data focused on one of these functions. Yet, in vivo the processes are intermixed.
R S, Taichman, M J, Reilly, S G, Emerson
openaire   +2 more sources

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

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