Results 111 to 120 of about 136,319 (308)

Highly Flexible and Conformable ZnO/FeGa Magnetoelectric Heterostructures for Skin wound Healing

Advanced Science, EarlyView.
The magnetic field‐induced electric field generated by a highly flexile ZnO(piezoelectric)/FeGa(magnetostrictive) magnetoelectric heterostructure embedded in the low Young's modulus elastomer PDMS has been used to stimulate the wound healing processes.
Filippos Perdikos, Laia Bagur, Cristina Vaca, Aritz Lafuente, Joaquin Llacer‐Wintle, Bojan Ambrožič, Christina Stefani, Minsoo Kim, Goran Dražić, Darja Lisjak, Jordi Sort, Xiang‐Zhong Chen, Maria Jose Esplandiu, Salvador Pané, Carme Nogués, Josep Nogués, Andreu Blanquer, Borja Sepúlveda   +17 more
wiley   +1 more source

Internalization of ACB-OBAb by osteoblasts.

, 2020
Upper Panel (scale 20μm)—The binding of ACB-OBAb to osteoblasts. (a) DIC image of osteoblast treated with ACB-OBAb. (b) ACB-OBAb stained (red) with AF555 secondary goat anti-mouse IgG. (c) The ACB-OBAb treated osteoblasts treated with DAPI (blue).
Jamil Azzi (613106), Said Mansour (8697699), Tahir Abdulrehman (8697696), Sini Skariah (130134), Ali Sultan (380590), Yousef Haik (2610628), Shahnaz Qadri (2610634)   +6 more
core   +1 more source

An Implantable Optogenetics‐Engineered Hydrogel for Amelioration of Rheumatoid Arthritis through Light‐Controlled Metabolic Reprogramming of Synovial Macrophages

Advanced Science, EarlyView.
An implantable hydrogel is designed to enable in situ and on‐demand secretion of GLP‐1 in synovium through blue light irradiation to activate GLP‐1R/HK2/VDAC1 pathway for upregulating tricarboxylic acid cycle and oxidative phosphorylation in macrophage, facilitating tissue repair and bone erosion recovery.
Dahai Hu, Yaru Sun, Qi Lu, Yi Zhang, Jieruo Li, Huige Hou, Huajun Wang, Hui Tang, Yunsong Zhang, Xiaofei Zheng, Qingsong Mei   +10 more
wiley   +1 more source

Gelatin-based biomaterials as a delivery strategy for osteosarcoma treatment

Frontiers in Pharmacology
Osteosarcoma is the most common primary malignant bone tumor. Although surgery and chemoradiotherapy have made some progress in the treatment of osteosarcoma.
Qifan Yang, Xingpeng Chen, Jing Liu, Yeteng He   +3 more
doaj   +1 more source

tBid‐Mediated Genetic Ablation of Connective Tissue Cells Reveals Their Key Regulatory Function During Limb Regeneration in Axolotls

Advanced Science, EarlyView.
We establish a tBid‐mediated cell ablation system in axolotls, achieve rapid and efficient ablation of multiple cell types, including muscle stem cell, spinal cord cell, and connective tissue (CT) cells. We investigate the role of CT using tBid‐mediated CT ablation and identify its essential role for limb development and regeneration.
Yan Hu, Weimin Feng, Zitian He, Jiayi Zeng, Jingyi Tang, Shulin Li, Tongbo Yu, Sulei Fu, Hui Ma, Binbin Lu, Yanmei Liu, Ji‐Feng Fei   +11 more
wiley   +1 more source

Differential effects of nanoselenium doping on healthy and cancerous osteoblasts in coculture on titanium

, 2010
In the present study, selenium (Se) nanoclusters were grown through heterogeneous nucleation on titanium (Ti) surfaces, a common orthopedic implant material.
Tran, PA, Tran, Phong A., Hurt, RH, Sarin, Love, Hurt, Robert H., Webster, Thomas J., Sarin, L, Webster, TJ   +7 more
core   +1 more source

Hyperlipidemia Aggravates Alveolar Bone Loss via Periodontal Ligament Stem Cell Ferroptosis Through GSK3β Dependent Ubiquitin‐Mediated NRF2 Degradation

Advanced Science, EarlyView.
Lipid metabolic stress triggers ferroptosis in PDLSCs through the GSK3β/NRF2 pathway, thereby aggravating periodontal bone loss. Upregulated GSK3β promotes NRF2 ubiquitination and proteasomal degradation via β‐TrCP, suppressing NRF2 nuclear translocation and antioxidant target expression.
Yuxiao Zhang, Xiangyao Wang, Yaxin Wu, Liping Liu, Gaoshaer Nuerlan, Ahsawle Ozathaley, Xiaorui Zhang, Jinping Wang, Bowen Yang, Jing Mao, Yan Liu, Shiqiang Gong   +11 more
wiley   +1 more source

CXCR4 is a response gene for parathyroid hormone which affects osteoblast and osteoclast function in vitro

Bone & Joint Research
Aims: To investigate the role of CXCR4 in response to teriparatide (TPTD) treatment in osteoblasts and osteoclasts. Methods: Primary murine and human osteoblasts and osteoclasts, MC3T3 cell lines, and hMSC-TERT4 cell lines were treated with TPTD and/or
Beatriz Larraz-Prieto, Louise Hjorth Lind, Jacob Bastholm Olesen, Asim Azfer, Morten Svarer Hansen, Morten Frost, Abbas Jafari, Stuart H. Ralston, Kent Søe, Nerea Alonso   +9 more
doaj   +1 more source

Bamboo‐Like Whiskers‐Reinforced Bioceramics Accelerate Large Segmental Bone Regeneration via Dual Modulation of Type‐H Vessels and Osteoinduction

Advanced Science, EarlyView.
The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng, Haibo Teng, Chuyao Xu, Jiaze He, Keting Liu, Xueying Li, Kai Zhang, Xiangdong Zhu, Xiangfeng Li, Jianguo Xu, Xingdong Zhang   +10 more
wiley   +1 more source

CCN3 increases BMP-4 expression and bone mineralization in osteoblasts

, 2012
[[abstract]]"The nephroblastoma overexpressed (NOV) gene, also called CCN3, regulates differentiation of skeletal mesenchymal cells. Bone morphogenetic proteins (BMPs) play important roles in osteoblast differentiation and bone formation, but the ...
黃元勵;Huang, Yuan-Li;Chen, YH;Tang, CH
core