Results 131 to 140 of about 112,140 (265)

Harnessing blood clot as a native scaffold for orchestrating tissue repairs and regeneration

BMEMat, EarlyView.
The blood clot, owing to its dynamic composition and unique microenvironment, holds significant yet underappreciated potential for tissue engineering. This review systematically summarizes the pathophysiology of clot formation, the key regulatory factors shaping its microenvironment, and its applications in both pre‐clinical and clinical settings ...
Gao‐peng Dang, Yu‐zhu Wang, Yi‐fei Wang, Que Bai, Jia‐xin Hao, Zhi‐ting Li, Xiao‐qing Cao, Yu Wei, Yue Feng, Ji‐hua Chen, Franklin R. Tay, Rui‐bing Wang, Jun‐ting Gu, Li‐na Niu   +13 more
wiley   +1 more source

Hijacking the bone niche: mechanistic insights into bone metastasis in breast cancer. [PDF]

Bone Res
Wu J, Deng M, Ye F, Deng W, Wu Z, Zheng X, Song C, Zou Y, Tang H.   +8 more
europepmc   +1 more source

Caveolin‐1 enriched apoptotic bodies derived from oral hard palate orchestrate bone remodeling to treat heterotopic ossification

BMEMat, EarlyView.
Downregulated CAV1 in HO is restored via apoptotic bodies from PMSCs, which reprogram bone remodeling by delivering CAV1 to target cells, highlighting the therapeutic role of EV subtypes in heterotopic ossification. Abstract Heterotopic ossification (HO) is a pathological process characterized by ectopic bone formation in non‐osseous tissues, with an ...
Yuchen Wang, Like Tang, Zhou Yu, Wenjin Cai, Qifeng Jiang, Zhikang Wang, Yitong Chen, Kaichen Lai, Ying Wang, Tim Forouzanfar, Chiyuan Ma, Gang Wu, Tingben Huang, Guoli Yang   +13 more
wiley   +1 more source

In vitro behaviour of osteoblast cells seeded into a COL/β-TCP composite scaffold

Open Life Sciences, 2008
Oprita Elena, Moldovan Lucia, Craciunescu Oana, Zarnescu Otilia   +3 more
doaj   +1 more source

Targeting N¹-methyladenosine modification in osteoblasts through tRNA methyltransferase 10C reverses mitochondrial dysfunction and ameliorates osteoporosis. [PDF]

Signal Transduct Target Ther
Sun H, Wang W, Zhang C, Zhang T, Yang X, Feng Y, Shan L, Yang Z, Zhang Y, Liu S, Wang W, Wang J, Hou X, Feng S.   +13 more
europepmc   +1 more source

Mechanism study of an articular cartilage repair material and its forward‐looking test for space medicine

BMEMat, EarlyView.
The regeneration process following dLhCG engraftment progressed through four distinct and interconnected stages. dLhCG maintained its regenerative efficacy after 6 months of cosmic exposure, supporting its potential application in space medicine.
Xu Hu, Hang Yao, Zhen Zhang, Zhonglian Wu, Huiqun Zhou, Bangheng Liu, Liang Ma, Yulei Mu, Dong‐An Wang   +8 more
wiley   +1 more source

Blocking interaction of sclerostin loop3 with osteoblastic LRP4 counteracts bone loss without increasing arterial stiffness during mechanical unloading. [PDF]

J Orthop Translat
Wang L, Zhang N, Jiang H, Tao X, Ma Y, Hu Z, Zhong C, Yang X, Yu S, Zhang H, Liu J, Yu Y, Liu F, Chen Z, Luo H, Ding S, Zhang Y, Sun M, Zhang S, Ferdinandy P, Yu R, Zhang T, Lu A, Qin L, Zhang S, Zhang B, Zhang G.   +26 more
europepmc   +1 more source

Multifunctional polycaprolactone‐based composite fibers with icariin and glutathione for effective repair of critical‐sized bone defects

BMEMat, EarlyView.
A multifunctional PCL‐based scaffold co‐delivering Icariin and Glutathione synergistically enhances osteogenesis, angiogenesis, and oxidative stress resistance, achieving near‐complete repair of critical‐sized bone defects in vivo. This cell‐free platform represents a promising strategy for accelerated bone regeneration.
Abdurohman Mengesha Yessuf, Yaqi Zhang, Bharat Prasad Sharma, Yake Wang, Tibebu Shiferaw Kassa, Abdul Qadir, Ye Jinqiu, Mohamedazeem M. Mohideen, Ahmed M. Salama, Weiguo Wang, Qidong Zhang, Yong Liu   +11 more
wiley   +1 more source

Path Analysis Results on Bone Markers That Influence Accelerated Bone Remodeling: An Experimental Study. [PDF]

Clin Exp Dent Res
Dewi RK, Oktawati S, Gani A, Suhartono E, Hamrun N, Samad R, Natsir N, Apriasari ML, Hasanuddin H.   +8 more
europepmc   +1 more source

Combination of autogenous dentin graft and allograft for horizontal ridge augmentation: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background Autogenous particulate dentin has emerged as one of the promising biocompatible alternatives to traditional bone graft materials in alveolar ridge augmentation. Although its clinical success is documented, comprehensive studies combining histological and radiographic evaluations remain limited. This case report addresses this gap by
Kosuke Kashiwagi, Yu‐Cheng Chang, Tun‐Jan Wang, Dumitru Gogarnoiu, Rodrigo Neiva   +4 more
wiley   +1 more source