Results 61 to 70 of about 136,319 (308)

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

Advanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir, Jixing Lin, Yuncang Li, Li Zhu, Paul F. A. Wright, Cuie Wen   +5 more
wiley   +1 more source

Primary cultures of chick osteocytes retain functional gap junctions between osteocytes and between osteocytes and osteoblasts

, 2008
The inaccessibility of osteocytes due to their embedment in the calcified bone matrix in vivo has precluded direct demonstration that osteocytes use gap junctions as a means of intercellular communication.
Sugawara, Yasuyo, Kamioka, Hiroshi, Murshid, Sakhr A., Ishihara, Yoshihito, Ris, Hans, Yamamoto, Teruko Takano, Lim, Soo-Siang   +6 more
core   +1 more source

Aerobic Glycolysis in Osteoblasts [PDF]

Current Osteoporosis Reports, 2014
Osteoblasts, the chief bone-making cells in the body, are a focus of osteoporosis research. Although teriparatide, a synthetic fragment of the human parathyroid hormone (PTH), has been an effective bone anabolic drug, there remains a clinical need for additional therapeutics that safely stimulates osteoblast number and function.
Emel, Esen, Fanxin, Long
openaire   +2 more sources

Packed for Ossification: High‐Density Bioprinting of hPDC Spheroids in HAMA Toward Endochondral Ossification

Advanced Healthcare Materials, EarlyView.
Human periosteum‐derived cell spheroids bioprinted at high density within a hyaluronic acid matrix promote fusion and hypertrophic cartilage formation in vitro. Early encapsulation enhances spheroid interaction and matrix maturation, generating scalable cartilage templates intended for endochondral bone regeneration.
Ane Albillos Sanchez, Maria Paula Marks, Paula Casademunt, Adrián Seijas‐Gamardo, Ioannis Papantoniou, Lorenzo Moroni, Carlos Mota   +6 more
wiley   +1 more source

G protein-coupled receptor 91 activations suppressed mineralization in Porphyromonas gingivalis–infected osteoblasts

Scientific Reports
Succinate receptor GPR91 is one of the G protein-coupled receptors (GPCRs) that interacts with various proteins to regulate diverse cellular functions such as cell morphology, apoptosis, and differentiation.
Wenqi Su, Dandan Zhang, Yujia Wang, Lang Lei, Houxuan Li   +4 more
doaj   +1 more source

A Fully Human Engineered Bone Niche With Endogenous Osteoclastogenesis Reveals Osteoclast‐Dependent Osteomimicry in Prostate Cancer Cells

Advanced Healthcare Materials, EarlyView.
A human 3D bone niche integrating osteoblasts and osteoclasts enables co‐culture with prostate cancer cell lines and patient‐derived organoids. The engineered niche (i) models aspects of reciprocal phenotypic regulation between osteoblasts and cancer cells, (ii) captures osteoclast‐enhanced osteomimicry in tumor cells, and (iii) establishes a ...
Andrea Mazzoleni, Robin Dolgos, Thomas Menter, Boris Dasen, Arnaud Scherberich, Clémentine Le Magnen, Manuele G. Muraro, Ivan Martin   +7 more
wiley   +1 more source

Development and transplantation of a mineralized matrix formed by osteoblasts in vitro for bone regeneration

, 2004
The use of extracellular matrix materials as scaffolds for the repair and regeneration of tissues is receiving increased attention. The current study was undertaken to test whether extracellular matrix formed by osteoblasts in vitro could be used as a ...
Bartold, P. Mark, Xiao, Y., Young, William G., Young, W., Bartold, P., Xiao, Yin, Haase, H., Hasse, Helen   +7 more
core   +1 more source

Transcriptional analysis of RTS osteoblasts and osteosarcoma.

, 2021
(A) Reactome analysis demonstrates enrichment of multiple canonical pathways in RTS compared to FC MSCs (D0), pre-osteoblasts (D15), and osteoblasts (D24). (B) Left, GO_BPs enriched in osteosarcoma by EnrichmentMap analysis. Network visualization of gene
Linchao Lu (11886284), Zhongming Zhao (40519), Yi-Hung Chen (1506184), Holger K. Eltzschig (11886302), Ruoji Zhou (11886290), Lisa L. Wang (11886305), Huihui Fan (182099), Ruiying Zhao (9752981), Christopher Vellano (7487243), Mo Liu (10658546), An Xu (24577), Jian Tu (490588), Erica L. Underwood (11886287), Benny Abraham Kaipparettu (411669), Zijun Huo (11886293), Nino Rainusso (10983403), Yitian Xu (5146028), Brittany E. Jewell (11886281), Mo-Fan Huang (9990698), Ying Liu (18461), Weidong Jin (3938906), Jun Hyoung Park (411671), Philip Jones (14235), Danielle A. Bazer (9990704), Dung-Fang Lee (9990710), Shu-Hsia Chen (11886296), Nathaniel K. Berg (11886299), Dandan Zhu (513418), Julian A. Gingold (9990701)   +28 more
core   +1 more source

3D‐Printed Piezoionic/Bioelectronic Hydrogel for Electro‐Metabolic Regulation of Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
A 3D‐printed piezoionic GPMx hydrogel enables stable electromechanical signal generation under mechanical loading, exhibiting long‐term durability and low fatigue. As a bioactive patch, it restores endogenous bioelectricity to stimulate osteogenesis via Ca2+ influx and mitochondrial activation, while simultaneously enabling label‐free alkaline ...
Sayan Deb Dutta, Myoung Joon Jeon, Youjin Seol, Ki‐Taek Lim   +3 more
wiley   +1 more source

Immunoinflammatory Mechanisms and Biocompatibility of Bioactive Dental Biomaterials: From Fundamental Insights to Clinical Translation

Advanced Healthcare Materials, EarlyView.
Surface‐host dialogue at the implant interface governs biological fate and osseointegration. Surface physicochemical properties of titanium (Ti) dental implants, including microgrooves, nanopatterns, nanotopography, roughness, and wettability, modulate the initial adsorption of proteins and the formation of a dynamic biointerface.
Daniela Moreira Cunha, Amanda Paino Santana, Marta Maria Alves Pereira, Mariana Martins Guerreiro, Jose Mauro Granjeiro, Jamil Awad Shibli, Jeroen J. J. P. van den Beucken, Anton Sculean, Rafael Scaf de Molon, Erica Dorigatti de Avila   +9 more
wiley   +1 more source