Results 161 to 170 of about 100,119 (298)

PARG inhibition suppresses osteoclast differentiation through transcriptional activation of an NRF2-dependent pathway. [PDF]

PLoS One
Sasaki Y, Nakatsuka R, Taniguchi R, Inoue A, Masutani M, Nozaki T.   +5 more
europepmc   +1 more source

Serum osteocalcin is associated with scintigraphic abnormalities in lame and clinically sound racehorses

Equine Veterinary Journal, EarlyView.
Abstract Background Musculoskeletal injury is a major welfare and economic challenge in racehorses, with stress‐related bone injury contributing to training interruption and catastrophic failure. Advanced imaging modalities can detect early skeletal pathology but remain limited in routine screening environments.
Peter Tually, Dominique Blache, Jack Meadows, Shiphrah Tagore, Paul O'Callaghan, Matilda Hathway, Ian Fulton, Geoffrey Currie   +7 more
wiley   +1 more source

In Silico and Experimental Evidence for Theasaponin E2 as a Modulator of the AKT1/GSK-3β Signaling Axis in Osteoclast Differentiation. [PDF]

Int J Mol Sci
Zhang L, Ding Y, Bao X, Deepak V.
europepmc   +1 more source

Untethered Electrical Stimulation Using Optoelectricity and Piezoelectricity for Tissue Regeneration

FlexTech, EarlyView.
Untethered electrical stimulation from optoelectronic and piezoelectric materials can aid regeneration of damaged tissue. ABSTRACT Electrical signals are increasingly recognized as important regulators of tissue development and regeneration, with outcomes linked to behaviors including proliferation, differentiation, cell migration, and more.
Ryan Yao, Baochun Xu, Cunjiang Yu
wiley   +1 more source

Oxidative Stress and Metabolic Reprogramming in Osteoclastogenesis: Molecular Mechanisms and Antioxidant Therapy for Bone Disorders. [PDF]

Antioxidants (Basel)
Alam MI, Farhana F, Khan TR, Sharmin F, Hurunnaher M, Katsuma Y, Sakai E, Sumita Y.   +7 more
europepmc   +1 more source

Viability of Tumor Cells in Bone Dust: Implications for Oncologic Skull Base Surgery

Head &Neck, EarlyView.
ABSTRACT Background Head and neck tumors with skull base involvement may require drilling of tumor infiltrated bone. We hypothesize that bone dust generated during this process contains viable tumor cells that may seed the surgical field. Methods Tumors with gross bone invasion were drilled, and dust was collected for H&E, cell viability analysis, and ...
Kelly Bridgham, Hani Samarah, Emma De Ravin, Hannah Kenny, Eric Mastrolonardo, Annie Moroco, Suhao Han, Oliver Abinader, Ramkrishna Mitra, Alban Linnenbach, Gurston Nyquist, Christopher Farrell, Stacey Gargano, Andrew P. South, Adam Luginbuhl   +14 more
wiley   +1 more source

Evidence-Calibrated Reanalysis of an Otosclerosis Locus Generates a Testable Myeloid State Hypothesis. [PDF]

Genes (Basel)
Ma W, Cheng Y, Li H, Lv H.
europepmc   +1 more source

Pregnancy‐ and lactation‐associated osteoporosis: A position statement of the IAPM, IOF, ECTS, ESCEO, IMS, and EMAS

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Pregnancy‐ and lactation‐associated osteoporosis (PLO) is a syndrome characterized by fragility fractures (most commonly vertebral, often multiple) occurring in late pregnancy or the early postpartum period. This position statement summarizes the current knowledge of PLO, and the recommended procedure for assessment, diagnosis and treatment ...
Peyman Hadji, Apostolos Athanasiadis, Maria‐Luisa Brandi, Marlene Chakhtoura, Manju Chandran, Frank Chervenak, Amos Grünebaum, Irene Lambrinoudaki, Willem F. Lems, Apostolos M. Mamopoulos, Eugene McCloskey, Rossella E. Nappi, Jessica Pepe, Jean‐Yves Reginster, René Rizzoli, Petra Stute, Şansın Tuzun, Amanda J. Vincent, Maria Belen Zanchetta, M. Carola Zillikens, Ioannis Kyvernitakis   +20 more
wiley   +1 more source

RUNX2 promotes osteoclast differentiation and bone resorption via the newly identified LncRNA-ROD: implications for alveolar remodeling. [PDF]

Int J Oral Sci
Li J, Liu Y, Qiao Y, Yan C, Zhao W, Ji L, Liu D, Xin Y, Zhang C, Wang X, Wang Y, Zheng S.   +11 more
europepmc   +1 more source

Cysteine Peptidases in Antitumor Immunity: Unraveling Antigen‐Presenting Cell Regulation and Therapeutic Potential

iMetaMed, EarlyView.
This review systematically summarizes the central role of cysteine peptidases in modulating antigen‐presenting cell (APC) function and antitumor immune responses, highlighting their critical significance in overcoming tumor immune evasion. Current research has established that cysteine peptidase subtypes, including cathepsins B, S, L, and X, exert ...
Yimao Wu, Xiaoyan Chen, Zichang Chen, Yalun Liang, Gokhan Zengin, Qian Zhang, Wenlong Sun, Meng‐Yao Li   +7 more
wiley   +1 more source