ASXL1 impairs osteoclast formation by epigenetic regulation of NFATc1 [PDF]
Abu-Amer, Yousef +6 more
core +1 more source
Histiocytosis development and clinical variation through the lens of genomics
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps +3 more
wiley +1 more source
cGAS-STING pathway mediation in osteoclast function and bone fracture healing. [PDF]
Zheng M +5 more
europepmc +1 more source
Under iron overload conditions, curcumin inhibits cellular senescence and promotes osteogenic differentiation by activating the NRF2/GPX4 signaling pathway in bone marrow mesenchymal stem cells (BMSCs), thereby preventing the onset of osteoporosis. ABSTRACT Dysregulated proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs ...
Jingmin Che +7 more
wiley +1 more source
Uridine inhibits ROS-mediated osteoclast differentiation and alleviates osteoporosis via modulation of PI3K/Akt-FoxO signaling. [PDF]
Bian S +10 more
europepmc +1 more source
The miR4261/PAMM axis in multiple myeloma promotes bone resorption. [PDF]
Cui J +7 more
europepmc +1 more source
Schematic Summary of Circadian Dysregulation in Arthritic Joints. This graphical abstract illustrates the key circadian disruptions observed in the collagen‑induced arthritis (CIA) model. The diagram depicts three main findings: (1) Nocturnal elevations in pro‑inflammatory cytokines (TNF‑α, IL‑6, IL‑17, IL‑1β, MIF) and bone‑destructive factors (DKK‑1 ...
Xiaogang Zhang +7 more
wiley +1 more source
5-methoxyresorcinol mitigates postmenopausal osteoporosis through regulation of the PI3K-AKT-GSK3β signaling pathway and ROS homeostasis. [PDF]
Yang M +6 more
europepmc +1 more source
Global Fluoride Toxicology Landscape: Bibliometric Approaches and Scientific Mapping
ABSTRACT This study analyzed research trends in the 100 most‐cited articles on fluoride toxicology, a topic widely debated due to the toxic effects associated with levels deemed safe for human exposure. A bibliometric analysis was conducted using the Web of Science‐Core Collection, extracting data such as citation count, authors, keywords, journal ...
Maria Karolina Martins Ferreira +8 more
wiley +1 more source
A novel <i>SLC2A10</i> gain-of-function variant links glycolytic macrophage polarization to chronic nonbacterial osteomyelitis. [PDF]
Li X, Shen L, Jia K, Chen S, An J.
europepmc +1 more source

