Results 161 to 170 of about 81,648 (311)

Hijacking the bone niche: mechanistic insights into bone metastasis in breast cancer. [PDF]

Bone Res
Wu J, Deng M, Ye F, Deng W, Wu Z, Zheng X, Song C, Zou Y, Tang H.   +8 more
europepmc   +1 more source

Corticosteroid Exposure in Chronic Rhinosinusitis and Global Airway Disease: Adrenal and Bone Impact

The Laryngoscope, EarlyView.
ABSTRACT Objective To investigate cumulative corticosteroid (CC) burden in patients with chronic rhinosinusitis with nasal polyps (CRSwNP), with or without coexisting asthma (global airway disease, GAD), referred for biologic treatment, and to assess the prevalence of CC‐related comorbidities, including secondary adrenal insufficiency, osteopenia and ...
Christiane Haase, Kjell Erik Julius Håkansson, Peter Schwarz, Kasper Aanæs, Jens Tidemandsen, Charlotte Suppli. Ulrik, Bente Appel Esbensen, Vibeke Backer   +7 more
wiley   +1 more source

Osteoclast Heterogeneity in Osteoarthritis: From Single-Cell Microenvironments to Program-Specific Therapeutic Opportunities. [PDF]

Int J Mol Sci
Tang T, Zhang P, Lin Z, Tang ZH, Chen D.
europepmc   +1 more source

Histiocytosis development and clinical variation through the lens of genomics

The Journal of Pathology, EarlyView.
Abstract Histiocytic neoplasms are rare haematologic diseases characterised by clonal expansions of cells with a monocyte, macrophage or dendritic cell phenotype. Their clinical manifestations are diverse, ranging from indolent lesions to aggressive systemic disease.
Paul G Kemps, Astrid GS van Halteren, Tom van Wezel, Pancras CW Hogendoorn   +3 more
wiley   +1 more source

cGAS-STING pathway mediation in osteoclast function and bone fracture healing. [PDF]

Front Immunol
Zheng M, Zhao L, Nian S, Wei Q, Zhou P, Tang H.   +5 more
europepmc   +1 more source

Development of Novel Models for Studying Osteoclasts

, 2014
Popular Abstract in English My PhD thesis has focused on increasing the understanding of the osteoclasts, the cells responsible for degradation of bone, by studying the rare hereditary disease autosomal recessive osteopetrosis (ARO).
Lund University., Thudium, Christian,
core  

SphK1/mitophagy axis in cementocytes drives orthodontic root resorption via mitochondrial transfer to osteoclasts. [PDF]

Bone Res
Wang H, Chen S, Chen S, Duan C, Zhu L, Lin H, Zou S, Li Y, Duan P.   +8 more
europepmc   +1 more source

BONE: Blocking Osteoclasts Using Novel Experimentation

, 2016
Bone and joint disorders caused by increased autoimmune bone resorption debilitate 27 million Americans who live with osteoarthritis (OA). The lifetime risk of developing OA of the knee and hip is about 46% and 25%, respectively. The normal function of
Parker, William, Elazizi, Mohamad, Speth, Robert, Hernandez, Maria, Goncalves, Flavia, Drukteinis, Saulius, Koutouzis, Theophilos, Mata, Valentina   +7 more
core  

Curcumin Alleviates the Osteogenesis Inhibition and the Aging Process in BMSCs Induced by Iron Overload Through Activating the NRF2/GPX4 Pathway

Phytotherapy Research, EarlyView.
Under iron overload conditions, curcumin inhibits cellular senescence and promotes osteogenic differentiation by activating the NRF2/GPX4 signaling pathway in bone marrow mesenchymal stem cells (BMSCs), thereby preventing the onset of osteoporosis. ABSTRACT Dysregulated proliferation and differentiation of bone marrow mesenchymal stem cells (BMSCs ...
Jingmin Che, Qing Feng, Zhixia Zhao, Jingying Sun, Weihao Ren, Yangmeng Feng, Cuixiang Xu, Xu‐Hui Li   +7 more
wiley   +1 more source

5-methoxyresorcinol mitigates postmenopausal osteoporosis through regulation of the PI3K-AKT-GSK3β signaling pathway and ROS homeostasis. [PDF]

Front Pharmacol
Yang M, Li R, Wang H, Geng Y, Yv Z, Qiao J, Li Y.   +6 more
europepmc   +1 more source