Results 171 to 180 of about 88,889 (259)

Recent Advances in Cryogel Applications for Musculoskeletal Regeneration

Medicinal Research Reviews, EarlyView.
ABSTRACT Hydrogels have been widely used in tissue engineering due to their high‐water content and biocompatibility, yet their densely cross‐linked microstructure inherently limits cell infiltration, mass transport, and mechanical support. Cryogels, formed through partial freezing and crosslinking under subzero conditions, provide unique 3D macroporous
Dohee Kim, Shinwon Kang, Hyejin Jo, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source

Effects of Zoledronate on Alveolar Bone and Teeth in Rats: Relationship Between Root Resorption and Occlusion. [PDF]

Int J Dent
Takahashi T, Iizuka T.
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

VIT-2763, a ferroportin-1 inhibitor, modulates osteoblast and osteoclast functions in hemizygous β^IVSII-654 knock-in thalassemic mice with osteopenia. [PDF]

Cell Death Discov
Aeimlapa R, Teerapornpuntakit J, Thongbunchoo J, Wattano P, Panmanee J, Svasti S, Charoenphandhu N.   +6 more
europepmc   +1 more source

Natural Products Exhibit Therapeutic Potential in Treating Rheumatoid Arthritis by Targeting the PI3K/Akt Signaling Pathway

Phytotherapy Research, EarlyView.
This review summarizes how natural products, mainly including flavonoids, terpenoids, alkaloids, and polyphenols alleviate RA via PI3K/Akt pathway, regulating inflammation, proliferation, apoptosis, angiogenesis, and osteoclast differentiation. The figure was created by Figdraw (https://www.figdraw.com/#/).
Haishuo Ren, Yige Wang, Wenjing Ma, Omachi Daniel Ogaji, Shujing Chen, Kunze Du, Xuemi Zhang, Bo Xu, Shanxing Zhai, Shiming Fang, Yanxu Chang   +10 more
wiley   +1 more source

Research Progress in Smart Hydrogel-Based Colloidal Systems for Osteoporosis Treatment. [PDF]

Int J Nanomedicine
Wang Z, Zhang J, Zhang B, Jiang Y.
europepmc   +1 more source

MACROPHAGE-COLONY-STIMULATING FACTOR STIMULATES SURVIVAL AND CHEMOTACTIC BEHAVIOR IN ISOLATED OSTEOCLASTS [PDF]

, 1993
J M Owens, T J Chambers, Owens, JM, A Wilson, C J Jagger, R Moss, Jagger, CJ, Chambers, TJ, K Fuller, Fuller, K, Wilson, A, Moss, R   +11 more
core   +1 more source

Natural Polysaccharides for Rheumatoid Arthritis Therapy: Mechanism, Drug Delivery and Clinical Application

Phytotherapy Research, EarlyView.
Schematic overview of the experimental models, therapeutic mechanisms, drug delivery systems, and clinical potential of natural polysaccharides in rheumatoid arthritis. ABSTRACT Rheumatoid arthritis (RA) is a systemic autoimmune disease characterized primarily by chronic synovitis.
Luxin Li, Junnan Li, Guangzhi Li, Lili Huang, Tiantian Wen, Yanying Li, Yan Sun, Zhenqiang Liu, Qingshan Chen, Lili Zhang, Tiangang Lu, Ruiyan Wu, Haixue Kuang, Xiaochi Ma, Yan Liu   +14 more
wiley   +1 more source

RUNX2 promotes osteoclast differentiation and bone resorption via the newly identified LncRNA-ROD: implications for alveolar remodeling. [PDF]

Int J Oral Sci
Li J, Liu Y, Qiao Y, Yan C, Zhao W, Ji L, Liu D, Xin Y, Zhang C, Wang X, Wang Y, Zheng S.   +11 more
europepmc   +1 more source

Herbal Therapeutics in Osteoporosis: Mechanisms, Evidence, and Translational Potential

Phytotherapy Research, EarlyView.
Schematic overview of bone remodeling dysregulation in osteoporosis and the multi‐target protective role of herbal therapeutics. ABSTRACT Osteoporosis is a chronic bone disease marked by reduced density and increased fracture risk. Current treatments face limitations in safety, efficacy, and long‐term adherence, prompting interest in alternative ...
Elnaz Vafadar Moradi, Sina Vossoughinia, Zahra Yazdanpanah, Hossein Sobhani, Jalileh Jalali, Mahboobeh Ghasemzadeh Rahbardar   +5 more
wiley   +1 more source