Abstract Background Bifidobacterium animalis subsp. lactis HN019 (B. lactis HN019) is a probiotic bacterial strain with immunomodulatory properties. Its benefits have been observed in healthy and systemically compromised animals with periodontitis (PD). Our objective was to investigate the local and systemic effects of the systemic administration of B.
Átila V. V. Nobre +10 more
wiley +1 more source
Cell signaling and transcriptional regulation of osteoclast lineage commitment, differentiation, bone resorption and diseases. [PDF]
Zhu S, Yan MQ, Masson A, Chen W, Li YP.
europepmc +1 more source
Abstract Background The pathogenesis and etiology of peri‐implantitis demand a deeper understanding to lead to successful treatment modalities. Animal models of peri‐implantitis pathogenesis offer unique insights but their translational impact requires consideration of implant biomaterials science.
Georgios Kotsakis +15 more
wiley +1 more source
The therapeutic potential of descending regulatory pathways from brain to bone in osteoporosis: focusing on the brain-bone axis. [PDF]
Rong Y +7 more
europepmc +1 more source
Abstract Background Titanium nanoparticle (TP) migration into peri‐implant bone may influence osseointegration. It remains unclear how loading protocols may affect TP distribution. This study aimed to detect TP in the bone around implants undergoing different loading protocols in Macaca fascicularis.
Fausto Zamparini +8 more
wiley +1 more source
Fibroblast-derived NEU1 as a therapeutic target for improving cortical bone integrity and fracture healing. [PDF]
Wu Y +9 more
europepmc +1 more source
Reduced prevalence of periodontitis in antidepressant users: Findings from a large‐scale US sample
Abstract Background Periodontitis and major depression disorder have been shown to have a bidirectional association. However, the impact of antidepressants, the primary pharmacological treatment for depression, on periodontal health remains unclear.
María Martínez +3 more
wiley +1 more source
MSDC-0160, a novel clinical-stage mitochondrial pyruvate carrier inhibitor, suppresses osteoclast differentiation and alleviates type 2 diabetes-related bone loss. [PDF]
Wang C +10 more
europepmc +1 more source
Dextran sodium sulfate confounds causal role of periodontitis in inflammatory bowel disease
Abstract Background Emerging evidence supports a bidirectional link between periodontitis and inflammatory bowel disease (IBD). To investigate this relationship, experimental models commonly use dextran sodium sulfate (DSS) to induce colitis. However, DSS is presumed to selectively affect the colon, and its potential off‐target effects on the oral ...
Himanshi Tanwar +11 more
wiley +1 more source
Constitutive activation of TGF-β receptor type I promotes cortical and cancellous bone formation in adult mice. [PDF]
Chotipinit T +6 more
europepmc +1 more source

