Results 261 to 270 of about 81,648 (311)
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Current Opinion in Rheumatology, 2004
It is now dogma that osteoclasts (OCs) arise from cells of the monocyte/macrophage lineage. However, data are accumulating suggesting that a relationship exists between B lymphocytes (B cells) and OC differentiation. Although the exact nature of this relation is unknown, it takes at least two forms.
Mark C, Horowitz, Joseph A, Lorenzo
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It is now dogma that osteoclasts (OCs) arise from cells of the monocyte/macrophage lineage. However, data are accumulating suggesting that a relationship exists between B lymphocytes (B cells) and OC differentiation. Although the exact nature of this relation is unknown, it takes at least two forms.
Mark C, Horowitz, Joseph A, Lorenzo
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Clinical Orthopaedics and Related Research, 1989
The origin of the osteoclast remains controversial even though investigations using light microscopy, tissue culture, electron microscopy, microcinematography, autoradiography, parabiosis, quail chick nuclear markers, giant lysosomal markers in beige mice, Y chromosomes, bone marrow cell culture, and monoclonal antibodies have been performed since its ...
H, Hanaoka, H, Yabe, H, Bun
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The origin of the osteoclast remains controversial even though investigations using light microscopy, tissue culture, electron microscopy, microcinematography, autoradiography, parabiosis, quail chick nuclear markers, giant lysosomal markers in beige mice, Y chromosomes, bone marrow cell culture, and monoclonal antibodies have been performed since its ...
H, Hanaoka, H, Yabe, H, Bun
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Transfection of Osteoclasts and Osteoclast Precursors
2011Osteoclasts and their precursors have traditionally been considered difficult cells to transfect using standard approaches. Here, we describe several methods for transfection of mature osteoclasts and their precursors using the Amaxa™ Nucleofector system, lentiviruses, and adenoviruses.
Julie C, Crockett +2 more
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Biological Reviews, 1949
SummaryOsteoclasts, Kölliker's universal agent of bone destruction, must still be regarded as enigmatical structures. It is likely that their life span is limited to a few days. Regarded by some as resulting from fusion of relatively immobile individuals of connective tissue type, and by others of mobile cells such as macrophages, it seems a ...
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SummaryOsteoclasts, Kölliker's universal agent of bone destruction, must still be regarded as enigmatical structures. It is likely that their life span is limited to a few days. Regarded by some as resulting from fusion of relatively immobile individuals of connective tissue type, and by others of mobile cells such as macrophages, it seems a ...
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Journal of Electron Microscopy, 2003
The mechanism by which bone collagen and other organic components are degraded by the osteoclast during osteoclastic bone resorption was unclear until the 1980s. Studies conducted since the early 1990s have identified lysosomal proteases, mainly cathepsins that are active at low pH, involved in osteoclastic bone resorption.
Tetsuya, Goto +2 more
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The mechanism by which bone collagen and other organic components are degraded by the osteoclast during osteoclastic bone resorption was unclear until the 1980s. Studies conducted since the early 1990s have identified lysosomal proteases, mainly cathepsins that are active at low pH, involved in osteoclastic bone resorption.
Tetsuya, Goto +2 more
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Clinical Orthopaedics and Related Research, 1979
The origin of the osteoclast has long been controversial. Various approaches such as traditional light microscopy, electron microscopy, microcinephotography, autoradiography, parabiosis, quail-chick nuclear marker, etc, have been used in attempts to resolve the problem.
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The origin of the osteoclast has long been controversial. Various approaches such as traditional light microscopy, electron microscopy, microcinephotography, autoradiography, parabiosis, quail-chick nuclear marker, etc, have been used in attempts to resolve the problem.
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Glucocorticoids and the Osteoclast
Annals of the New York Academy of Sciences, 2007Abstract: Glucocorticoid (GC)‐induced bone loss is the most common cause of secondary osteoporosis but its pathogenesis is controversial. GCs clearly suppress bone formation in vivo but the means by which they impact osteoblasts is unclear. Because bone remodeling is characterized by tethering of the activities of the two cells, the osteoclast is a ...
Hyun-Ju, Kim +7 more
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Annals of the New York Academy of Sciences, 2010
Thirty‐five years ago it had become clear that the osteoclast was not a bone cell but an immigrant into bone, derived from the hemopoietic system. Among hemopoietic cells, mononuclear phagocytes seemed the most likely precursors. However, for the progeny of wandering cells such as those to achieve nonrandom localization implies control by the local ...
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Thirty‐five years ago it had become clear that the osteoclast was not a bone cell but an immigrant into bone, derived from the hemopoietic system. Among hemopoietic cells, mononuclear phagocytes seemed the most likely precursors. However, for the progeny of wandering cells such as those to achieve nonrandom localization implies control by the local ...
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Journal of Dental Research, 1966
SYNOPSIS IN INTERLINGUA HISTOGENESE DE OSTEOCLASTAS.— Rattos blanc esseva subjicite a duo injectiones de 200 unitates de Parathormon con un intervallo de 12 horas. Tres horas post le prime injection, thymidina a tritium esseva administrate.
P D, Toto, J J, Magon
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SYNOPSIS IN INTERLINGUA HISTOGENESE DE OSTEOCLASTAS.— Rattos blanc esseva subjicite a duo injectiones de 200 unitates de Parathormon con un intervallo de 12 horas. Tres horas post le prime injection, thymidina a tritium esseva administrate.
P D, Toto, J J, Magon
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