Results 261 to 270 of about 134,929 (355)

Solasodine, a Natural Steroidal Alkaloid, Attenuates RANKL-Induced Osteoclastogenesis and Bone Resorption: A Study Based on Network Pharmacology and Experimental Validation. [PDF]

J Cell Mol Med
Jiang Y, Jin Z, Ji X, Wang M, Cao Z.
europepmc   +1 more source

Bone health in adults with non‐ambulatory neuromuscular disorders: scoping review of risk factors, diagnosis and management

Internal Medicine Journal, EarlyView.
Abstract Background Non‐ambulatory adults have an increased risk of osteoporosis and fractures due to reduced weight‐bearing and diminished neuromuscular stimulation, resulting in substantial morbidity and mortality. Aims This scoping review aimed to systematically evaluate risk factors, diagnostic indicators and management strategies for optimising ...
Thomas Bailey, Carolyn Droste, John A. Eisman, Steven G. Faux, Arnagretta Hunter   +4 more
wiley   +1 more source

Lactate regulates osteoclastogenesis via H3k18la in osteoarthritis. [PDF]

Int J Mol Med
Fan Z, Fu Q, Sun T, Zhong Y, Ma Y, Jian J, Yuan S, Li S, Xu X.   +8 more
europepmc   +1 more source

The role of Kindlin-3 in cells of the haematopoietic system [PDF]

, 2011
Schmidt, Sarah Marianne
core  

Denosumab discontinuation and fracture risk: getting the balance right

Internal Medicine Journal, EarlyView.
Abstract Denosumab is a highly effective therapy for osteoporosis. Since its approval by the Therapeutic Goods Administration (TGA) in 2010, use of denosumab has surged across Australia, delivering substantial fracture‐prevention benefits to tens of thousands of patients. However, stopping denosumab may lead to acute loss of bone with an increased risk
Albert S. Kim, Christian M. Girgis
wiley   +1 more source

TSP-1 interaction with RANK and OPG: implications for bone remodeling and osteolytic bone metastasis. [PDF]

Cell Death Dis
Carminati L, Sangalli F, Urbinati C, Longhi E, Tomasoni G, Borsotti P, Midwood KS, Carlessi E, Rusnati M, Taraboletti G.   +9 more
europepmc   +1 more source

Local Sodium Tanshinone IIA Sulfonate Attenuates Periodontal Bone Loss by Modulating Inflammatory, Immune and Osteoclastogenic Signalling

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To investigate whether local administration of sodium tanshinone IIA sulfonate (STS) modulates periodontal inflammation, alveolar bone loss, immune response and bone remodelling–related signalling pathways in a ligature‐induced murine model of periodontitis.
Rafael Scaf de Molon, Raquel Mantuaneli Scarel‐Caminaga, François Isnaldo Dias Caldeira, Edilson Ervolino, Erica Dorigatti de Avila, Paula Aboud Barbugli, Gabriela Ezequiel Oliveira, Joao Pedro Franco‐Moura, Leticia Helena Theodoro, Joni Augusto Cirelli, Sotirios Tetradis, Alpdogan Kantarci   +11 more
wiley   +1 more source

Optimizing <i>in vitro</i> osteoclastogenesis: bone marrow-derived macrophages differentiation and cell density as critical determinants. [PDF]

PeerJ
Li J, Sun X, Yan C, Zhao W, Liu D, Liu Y, Zheng S.   +6 more
europepmc   +1 more source

Scaling relationships between Haversian canal‐to‐secondary osteon and midshaft femur cortical‐to‐total area in a human autopsy sample

Journal of Anatomy, EarlyView.
We report that femoral cortical thickness was strongly and negatively associated with secondary osteon porosity in an Australian autopsy sample, indicating that thicker cortices contained less porous secondary osteons. This allometric relationship held for the whole sample, males and sedentary well‐nourished individuals, but not for females or other ...
Justyna J. Miszkiewicz, Laura A. B. Wilson, Karen M. Cooke, Rita Hardiman   +3 more
wiley   +1 more source