Results 11 to 20 of about 138,476 (311)
Biomolecules, 2021 Human skin fibroblasts (HSFs) approximate the multidirectional differentiation potential of mesenchymal stem cells, so they are often used in differentiation, cell cultures, and injury repair. They are an important seed source in the field of bone tissue
Xiaolan Huang +12 more
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Osteogenic Differentiation in Healthy and Pathological Conditions [PDF]
International Journal of Molecular Sciences, 2016 This review focuses on the osteogenic differentiation of mesenchymal stem cells (MSC), bone formation and turn-over in good and ill skeletal fates. The interacting molecular pathways which control bone remodeling in physiological conditions during a lifelong process are described.
VALENTI, Maria Teresa +2 more
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Resveratrol mediated modulation of Sirt-1/Runx2 promotes osteogenic differentiation of mesenchymal stem cells: potential role of Runx2 deacetylation. [PDF]
, 2012 Osteogenic repair in response to bone injury is characterized by activation and differentiation of mesenchymal stem cells (MSCs) to osteoblasts.
Aldinger, Constance +6 more
core +10 more sources
Dynamic and distinct histone modifications of osteogenic genes during osteogenic differentiation [PDF]
Journal of Biochemistry, 2015 Many skeletal diseases have common pathological phenotype of defective osteogenesis of bone marrow stromal cells (BMSCs), in which histone modifications play an important role. However, few studies have examined the dynamics of distinct histone modifications during osteogenesis. In this study, we examined the dynamics of H3K9/K14 and H4K12 acetylation;
Yong-Xing, Zhang +5 more
openaire +2 more sources
Scientific Reports, 2022 Human mesenchymal stem cells (hMSCs) have great potential in cell-based therapies for tissue engineering and regenerative medicine due to their self-renewal and multipotent properties.
Yuwen Zhao +4 more
doaj +1 more source
Journal of Investigative Surgery, 2022 Background: Degenerative disk disease (DDD) remains the leading incentive of severe lumbago. DDD is mainly caused by degeneration of cartilage endplate (CEP).
Yunsheng Chen +5 more
doaj +1 more source
Scientific Reports, 2021 Mesenchymal stem cells (MSCs) are important in regenerative medicine because of their potential for multi-differentiation. Bone marrow, chorion and placenta have all been suggested as potential sources for clinical application.
Kulisara Marupanthorn +4 more
doaj +1 more source
Mesenchymal stem cell-derived exosomes have altered microRNA profiles and induce osteogenic differentiation depending on the stage of differentiation. [PDF]
PLoS ONE, 2018 Human mesenchymal stem cell (hMSC)-derived exosomes have shown regenerative effects, but their role in osteogenesis and the underlying mechanism are yet to be determined.
Xiaoqin Wang +4 more
doaj +1 more source
Utilizing osteocyte derived factors to enhance cell viability and osteogenic matrix deposition within IPN hydrogels [PDF]
, 2020 Many bone defects arising due to traumatic injury, disease, or surgery are unable to regenerate, requiring intervention. More than four million graft procedures are performed each year to treat these defects making bone the second most commonly ...
Hoey, David A. +2 more
core +1 more source
Osteogenic Differentiation of Dental Follicle Stem Cells [PDF]
International Journal of Medical Sciences, 2012 Stem cells are defined as clonogenic cells capable of self-renewal and multi-lineage differentiation. A population of these cells has been identified in human Dental Follicle (DF). Dental Follicle Stem Cells (DFSCs) were found in pediatric unerupted wisdom teeth and have been shown to differentiate, under particular conditions, into various cell types ...
Mori G +11 more
openaire +3 more sources