Results 31 to 40 of about 139,682 (311)

Interleukin-6/interleukin-6 receptor complex promotes osteogenic differentiation of bone marrow-derived mesenchymal stem cells

Stem Cell Research & Therapy, 2018
Background Interleukin-6 (IL-6) with IL-6 receptor (IL-6R) play an important role in the tissue regeneration in vivo, especially bone metabolism. Bone marrow -derived mesenchymal stem cells (BM-MSCs) are multipotent stromal cells, which are main origin ...
Zhongyu Xie, Su’an Tang, Guiwen Ye, Peng Wang, Jinteng Li, Wenjie Liu, Ming Li, Shan Wang, Xiaohua Wu, Shuizhong Cen, Guan Zheng, Mengjun Ma, Yanfeng Wu, Huiyong Shen   +13 more
doaj   +1 more source

Ucma/GRP inhibits phosphate-induced vascular smooth muscle cell calcification via SMAD-dependent BMP signalling [PDF]

, 2011
Vascular calcification (VC) is the process of deposition of calcium phosphate crystals in the blood vessel wall, with a central role for vascular smooth muscle cells (VSMCs). VC is highly prevalent in chronic kidney disease (CKD) patients and thought, in
A Tagariello, AK Cheung, AN Kapustin, AP Sage, BA Willems, C Hough, C Surmann-Schmitt, C-H Heldin, CA Gregory, CM Giachelli, CM Shanahan, CM Shanahan, CM Shanahan, CR Dhore, CS Viegas, CS Viegas, CS Viegas, D Proudfoot, E Neven, F Guerrero, F Liu, JL Hunt, KM McCabe, LJ Schurgers, LJ Schurgers, LS Shankman, M Jeune Le, M Mizobuchi, MG Frid, MJ Duer, ML Chatrou, MR Alexander, MS Rafael, MY Speer, N Eitzinger, QQ Huang, R Shroff, RJ Rennenberg, S Feil, S Jono, S Olechnowicz-Tietz, SA Steitz, T Cai, T Lin, VA Jesus Perez de, VP Iyemere, X Li, Y Liu, YJ Lee   +48 more
core   +2 more sources

Graphene-based nanomaterials for tissue engineering in the dental field [PDF]

, 2018
The world of dentistry is approaching graphene-based nanomaterials as substitutes for tissue engineering. Apart from its exceptional mechanical strength, electrical conductivity and thermal stability, graphene and its derivatives can be functionalized ...
Antoniac, I, Bellin, G, Bressan, E, Ferroni, L, Gardin, C, Guazzo, R, Ludovichetti, FRANCESCO SAVERIO, Piattelli, A, Sbricoli, L, Zavan, B   +9 more
core   +1 more source

Osteogenic growth peptide enhances osteogenic differentiation of human periodontal ligament stem cells

Heliyon, 2022
Bone tissue engineering consists of three major components namely cells, scaffolds, and signaling molecules to improve bone regeneration. These integrated principles can be applied in patients suffered from bone resorption diseases, such as osteoporosis and periodontitis.
Steven Dwi Purbantoro, Thanaphum Osathanon, Sirirat Nantavisai, Chenphop Sawangmake   +3 more
openaire   +3 more sources

The galectin-3/RAGE dyad modulates vascular osteogenesis in atherosclerosis [PDF]

, 2013
Vascular calcification correlates with inflammation and plaque instability in a dual manner, depending on the spotty/granular (micro) or sheet-like/lamellated (macro) pattern of calcification.
BLASETTI FANTAUZZI, Claudia, Carlo M., Pesce, Familiari, Giuseppe, Iacobini, Carla, Menini, Stefano, Pugliese, Giuseppe, Relucenti, Michela, Ricci, Carlo, Salvi, Laura, Taurino, Maurizio   +9 more
core   +1 more source

Oral fibroblasts rescue osteogenic differentiation of mesenchymal stem cells after exposure to Zoledronic acid in a paracrine effect

Frontiers in Pharmacology, 2023
Background: Medication-related osteonecrosis of the jaw is a serious complication that develops in oncologic patients treated with Zoledronic acid. Although used for over 30 years, the influence of Zoledronic acid on bone has been thoroughly investigated,
Tal Berg, Tal Berg, Ofri Doppelt-Flikshtain, Ofri Doppelt-Flikshtain, Benjamin R. Coyac, Benjamin R. Coyac, Hadar Zigdon-Giladi, Hadar Zigdon-Giladi, Hadar Zigdon-Giladi   +8 more
doaj   +1 more source

A perfusion culture system for assessing bone marrow stromal cell differentiation on PLGA scaffolds for bone repair [PDF]

, 2018
Biomaterials development for bone repair is currently hindered by the lack of physiologically relevant in vitro testing systems. Here we describe the novel use of a bi-directional perfusion bioreactor to support the long term culture of human bone marrow
Alini, Mauro, Bara, Jennifer J, Bardsley, Katie, El Haj, Alicia J, Moser, Caroline, Stoddart, Martin J   +5 more
core   +2 more sources

Nanotopological plate stimulates osteogenic differentiation through TAZ activation [PDF]

Scientific Reports, 2017
AbstractThe topographical environment, which mimics the stem cell niche, provides mechanical cues to regulate the differentiation of mesenchymal stem cells (MSC). Diverse topographical variations have been engineered to investigate cellular responses; however, the types of mechanical parameters that affect cells, and their underlying mechanisms remain ...
Hwang, Jun-Ha, Lee, Dong-Hyun, Byun, Mi Ran, Kim, A. Rum, Kim, Kyung Min, Il Park, Jung, Oh, Ho Taek, Hwang, Eun Sook, Lee, Kyu Back, Hong, Jeong-Ho   +9 more
openaire   +4 more sources

LncRNA TCONS_00023297 Regulates the Balance of Osteogenic and Adipogenic Differentiation in Bone Marrow Mesenchymal Stem Cells and the Coupling Process of Osteogenesis and Angiogenesis

Frontiers in Cell and Developmental Biology, 2021
Long noncoding RNA (lncRNA) is a noncoding RNA with a length of more than 200 bases. It plays an important role in the occurrence and development of diseases. Research on lncRNAs has received increasing attention.
Haitao Wang, Peng Wei, Yi Zhang, Yuebai Li, Li Yin   +4 more
doaj   +1 more source

Adipose-derived stem cells: a review of osteogenesis differentiation [PDF]

, 2016
Second part of manuscript based on osteogenesis differentiation of stem cells. Bones are highly regenerative organs but there are still many problems with therapy of large bone defects.
Mazurek, Urszula, Sikora, Bartosz, Skubis, Aleksandra, Wojdas, Emilia, Zmarzły, Nikola   +4 more
core   +2 more sources