Results 11 to 20 of about 139,682 (311)
Bioactive Materials, 2020 Osteogenic differentiation is the basis of bone growth and repair related to many diseases, in which evaluating the degree and ability of osteogenic transformation is quite important and highly desirable.
Zhenyu Zheng +8 more
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Patterned Piezoelectric Scaffolds for Osteogenic Differentiation [PDF]
International Journal of Molecular Sciences, 2020 The morphological clues of scaffolds can determine cell behavior and, therefore, the patterning of electroactive polymers can be a suitable strategy for bone tissue engineering. In this way, this work reports on the influence of poly(vinylidene fluoride-co-trifluoroethylene) (P(VDF-TrFE)) electroactive micropatterned scaffolds on the proliferation and ...
Teresa Marques-Almeida +4 more
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Bisindoylmaleimide I enhances osteogenic differentiation [PDF]
Protein & Cell, 2012 The Wnt/β-catenin and bone morphogenetic proteins (BMPs) pathways play important roles in controlling osteogenesis. Using a cell-based kinase inhibitor screening assay, we identified the compound bisindoylmaleimide I (BIM) as a potent agonist of the cytosolic β-catenin accumulation in preosteoblast cells. Through suppressing glycogen synthase kinase 3β
Zhou, F.F., Huang, H.Z., Zhang, L.
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Histone modifications centric-regulation in osteogenic differentiation [PDF]
Cell Death Discovery, 2021 AbstractHistone modification critically contributes to the epigenetic control of gene expression by changing the configuration of chromatin and modifying the access of transcription factors to gene promoters. Recently, we observed that histone acetylation and crotonylation mediated the expression of endocytosis-related genes and tumor-related immune ...
Kun Li, Jinxiang Han, Ziqiang Wang
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The Regulatory Landscape of Osteogenic Differentiation [PDF]
Stem Cells, 2014 AbstractDifferentiation of osteoblasts from mesenchymal stem cells (MSCs) is an integral part of bone development and homeostasis, and may when improperly regulated cause disease such as bone cancer or osteoporosis. Using unbiased high-throughput methods we here characterize the landscape of global changes in gene expression, histone modifications, and
Anne-Mari, Håkelien +8 more
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Osteogenic Differentiation in Healthy and Pathological Conditions [PDF]
International Journal of Molecular Sciences, 2016 This review focuses on the osteogenic differentiation of mesenchymal stem cells (MSC), bone formation and turn-over in good and ill skeletal fates. The interacting molecular pathways which control bone remodeling in physiological conditions during a lifelong process are described.
VALENTI, Maria Teresa +2 more
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Dynamic and distinct histone modifications of osteogenic genes during osteogenic differentiation [PDF]
Journal of Biochemistry, 2015 Many skeletal diseases have common pathological phenotype of defective osteogenesis of bone marrow stromal cells (BMSCs), in which histone modifications play an important role. However, few studies have examined the dynamics of distinct histone modifications during osteogenesis. In this study, we examined the dynamics of H3K9/K14 and H4K12 acetylation;
Yong-Xing, Zhang +5 more
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Osteogenic Differentiation of Dental Follicle Stem Cells [PDF]
International Journal of Medical Sciences, 2012 Stem cells are defined as clonogenic cells capable of self-renewal and multi-lineage differentiation. A population of these cells has been identified in human Dental Follicle (DF). Dental Follicle Stem Cells (DFSCs) were found in pediatric unerupted wisdom teeth and have been shown to differentiate, under particular conditions, into various cell types ...
Mori G +11 more
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Bioactive sphene-based ceramic coatings on cpTi substrates for dental implants: An in vitro study [PDF]
, 2018 Titanium implant surface modifications have been widely investigated to favor the process of osseointegration. The present work aimed to evaluate the effect of sphene (CaTiSiO5) biocoating, on titanium substrates, on the in vitro osteogenic ...
Badocco, Denis +8 more
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Cells, 2022 Osteoporosis, or steroid-induced osteonecrosis of the hip, is accompanied by increased bone marrow adipogenesis. Such a disorder of adipogenic/osteogenic differentiation, affecting bone-marrow-derived mesenchymal stem cells (BMSCs), contributes to bone ...
Chenglong Wang +7 more
doaj +1 more source