Results 21 to 30 of about 139,682 (311)

Interleukin-18 enhances vascular calcification and osteogenic differentiation of vascular smooth muscle cells through TRPM7 channel activation [PDF]

, 2017
Objective—Vascular calcification (VC) is an important predictor of cardiovascular morbidity and mortality. Osteogenic differentiation of vascular smooth muscle cells (VSMCs) is a key mechanism of VC. Recent studies show that IL-18 (interleukin-18) favors
Chen, Jie, Chen, Renhua, Feng, Weijing, Huang, Hui, Touyz, Rhian M., Wang, Jingfeng, Zhang, Kun, Zhang, Yinyin   +7 more
core   +1 more source

Expression of fibroblast growth factor receptor and its role in regulating osteoblast differentiation

Di-san junyi daxue xuebao, 2019
Objective To investigate the changes in the expression of fibroblast growth factor receptors 1-3 (FGFR1-3) at different stages of osteogenic differentiation and clarify the role of FGFR signaling in osteogenic differentiation.
MO Qifei, YANG Peng, SU Nan, CHEN Lin
doaj   +1 more source

BRD4 facilitates osteogenic differentiation of human bone marrow mesenchymal stem cells through WNT4/NF-κB pathway

Journal of Orthopaedic Surgery and Research, 2023
Background Human bone marrow mesenchymal stem cells (hBMSCs) are a major source of osteoblast precursor cells and are directly involved in osteoporosis (OP) progression.
Tao Ning, Huihui Guo, Mingming Ma, Zhengang Zha   +3 more
doaj   +1 more source

Pluronic F-127 hydrogel as a promising scaffold for encapsulation of dental-derived mesenchymal stem cells. [PDF]

, 2015
Dental-derived mesenchymal stem cells (MSCs) provide an advantageous therapeutic option for tissue engineering due to their high accessibility and bioavailability.
Ansari, Sahar, Chen, Chider, Diniz, Ivana MA, Marques, Márcia M, Moshaverinia, Alireza, Shi, Songtao, Xu, Xingtian, Zadeh, Homayoun H   +7 more
core   +1 more source

Adipokines regulate mesenchymal stem cell osteogenic differentiation

World Journal of Stem Cells, 2023
Mesenchymal stem cells (MSCs) can differentiate into various tissue cell types including bone, adipose, cartilage, and muscle. Among those, osteogenic differentiation of MSCs has been widely explored in many bone tissue engineering studies. Moreover, the conditions and methods of inducing osteogenic differentiation of MSCs are continuously advancing ...
Xu, Zhong-Hua, Xiong, Chen-Wei, Miao, Kai-Song, Yu, Zhen-Tang, Zhang, Jun-Jie, Yu, Chang-Lin, Huang, Yong, Zhou, Xin-Die   +7 more
openaire   +2 more sources

Adhesive and mechanical regulation of mesenchymal stem cell differentiation in human bone marrow and periosteum-derived progenitor cells [PDF]

, 2012
It has previously been demonstrated that cell shape can influence commitment of human bone marrow-derived mesenchymal stem cells (hBMCs) to adipogenic, osteogenic, chondrogenic, and other lineages.
Chen, Christopher S., Eyckmans, Jeroen, Lin, Grace L.   +2 more
core   +2 more sources

Osteogenic differentiation of fibroblast-like synovial cells in rheumatoid arthritis is induced by microRNA-218 through a ROBO/Slit pathway

Arthritis Research & Therapy, 2018
Background Fibroblast-like synovial cells (FLS) have multilineage differentiation potential including osteoblasts. We aimed to investigate the role of microRNAs during the osteogenic differentiation of rheumatoid arthritis (RA)-FLS.
Naoki Iwamoto, Shoichi Fukui, Ayuko Takatani, Toshimasa Shimizu, Masataka Umeda, Ayako Nishino, Takashi Igawa, Tomohiro Koga, Shin-ya Kawashiri, Kunihiro Ichinose, Mami Tmai, Hideki Nakamura, Tomoki Origuchi, Ko Chiba, Makoto Osaki, Astrid Jüngel, Steffen Gay, Atsushi Kawakami   +17 more
doaj   +1 more source

Enhanced Osteogenic Differentiation in Zoledronate-Treated Osteoporotic Patients [PDF]

International Journal of Molecular Sciences, 2017
Bisphosphonates are well known inhibitors of osteoclast activity and thus may be employed to influence osteoblast activity. The present study was designed to evaluate the in vivo effects of zoledronic acid (ZA) on the proliferation and osteoblastic commitment of mesenchymal stem cells (MSC) in osteoporotic patients.
DALLE CARBONARE, Luca Giuseppe, MOTTES, Monica, MALERBA, Giovanni, MORI, Antonio, Zaninotto, Martina, Plebani, Mario, Dellantonio, Alessandra, VALENTI, Maria Teresa   +7 more
openaire   +2 more sources

Evaluation of Current Studies to Elucidate Processes in Dental Follicle Cells Driving Osteogenic Differentiation

Biomedicines, 2023
When research on osteogenic differentiation in dental follicle cells (DFCs) began, projects focused on bone morphogenetic protein (BMP) signaling. The BMP pathway induces the transcription factor DLX3, whichh in turn induces the BMP signaling pathway via
Christian Morsczeck, Michela De Pellegrin, Anja Reck, Torsten E. Reichert   +3 more
doaj   +1 more source

Impaired osteoblast differentiation in annexin A2- and -A5-deficient cells. [PDF]

, 2014
Annexins are a class of calcium-binding proteins with diverse functions in the regulation of lipid rafts, inflammation, fibrinolysis, transcriptional programming and ion transport.
Genetos, Damian C, Karin, Norman J, Weber, Thomas J, Wong, Alice, Yellowley, Clare E   +4 more
core   +4 more sources