Results 221 to 230 of about 148,060 (339)

Dual‐Anchored Clickable Peptide via SPAAC for Gelatinase‐Responsive Antibacterial and Osteogenic Functions on Titanium Implants

Advanced Science, EarlyView.
To address the infection‐associated orthopedic implant failures, this study presents a gelatinase‐responsive antibacterial titanium implant (Ti‐Dual) featuring a dual‐anchored fusion peptide containing antibacterial (HHC36) and osteogenic (RGD) domains connected by a cleavable GPLGV linker.
Ru Zhong, Hang Zhou, Chenyang Ye, Lei Chu, Lin Wang, Yingjun Wang   +5 more
wiley   +1 more source

Bone-Derived dECM Hydrogels Support Tunable Microenvironments for In Vitro Osteogenic Differentiation. [PDF]

Adv Healthc Mater
Dekker M, Hipwood L, Ravichandran A, Hutmacher DW, Meinert C, McGovern J.   +5 more
europepmc   +1 more source

Sustained Mg/Sr ion delivery from injectable silk fibroin hydrogels drives SCAP osteogenic differentiation

Chen Chen, Zeyu Gao, Yuman Li, Tuanfeng Zhou, Huimin Zheng, Shengjie Jiang, Yue Yang, Yan Wei   +7 more
openalex   +1 more source

Cascade Therapy of Periodontitis via Sequential Release of Ribosome‐Targeting Antimicrobial Peptide and Irisin From a Multifunctional MOF‐Based System

Advanced Science, EarlyView.
This study presents a novel strategy for periodontitis treatment by co‐delivering a membrane‐ and ribosome‐targeting antimicrobial peptide GF and Irisin through a pH‐responsive metal‐organic framework. The system enables sequential release, providing rapid antibacterial action, anti‐inflammatory and antioxidative effects, as well as promoting bone ...
Yan Chen, Zheng Xu, Yunmo Xue, Shanshan Liu, Xiang Zhang, Jingyao Guo, Minhui Yao, Yue Liu, Xiaolin Lu, Jieshu Qian, Qian Ma   +10 more
wiley   +1 more source

Application of Machine Learning in Predicting Osteogenic Differentiation of Mesenchymal Stem Cells. [PDF]

Bioengineering (Basel)
Mao H, Zhou Z, Yang Y, Lin K, Zhou C, Wang X.   +5 more
europepmc   +1 more source

Recombinant human osteogenic protein-1 (hOP-1) induces new bone formation in vivo with a specific activity comparable with natural bovine osteogenic protein and stimulates osteoblast proliferation and differentiation in vitro.

, 1992
T. Kuber Sampath, James C. Maliakal, Peter V. Hauschka, William K. Jones, Halina Sasak, R F Tucker, Kerry White, John E. Coughlin, Marjorie Tucker, Ruo-dan Pang   +9 more
openalex   +1 more source

Curcumin Regulates the Osteogenic Differentiation of Rat Bone Marrow Mesenchymal Stem Cells via Bmp2, Ocn, Opn, Osterix, Runx2

, 2023
Canbin Zhao, Chao Guo, Juncheng Li, Hongzhang Sun, Huixi Wang, Zhengwei Luo, Zhongyi Guo, Donghui Guan, Xiaolong Yan   +8 more
openalex   +1 more source

Co‐Treatment With rhBMP‐2 and Rapamycin Modulates Osteogenesis–Adipogenesis Balance to Enhance Aged Bone Regeneration

Advanced Science, EarlyView.
This study demonstrates that the imbalance between osteogenic and adipogenic differentiation in senescent BMSCs, leading to excessive adipocyte accumulation, which subsequently impairs bone regeneration in aged mice. To address this pathological dysregulation, a novel energy‐supplying hydrogel system (PBR) has been developed to restore balanced ...
Zirui He, Xiaoqiao Bai, Fangru Xie, Xuan Wang, Fan Zhang, Yuanman Yu, Yuan Yuan, Changsheng Liu   +7 more
wiley   +1 more source

Mitochondrial regulation of stem cell osteogenic differentiation: A key driver for bone regeneration. [PDF]

World J Stem Cells
Lu JS, Zhao YH, Mu FY, Song CY, Yang M, Huang YS, Wang KY.   +6 more
europepmc   +1 more source

Pearl‐Like Bioinspired Coating Enables Regulation of Mg Degradation for Osteoporotic Bone Repair

Advanced Science, EarlyView.
In this study, inspired by pearl architecture, we developed a layered Ca–P “brick” and Fn‐mimetic peptide “mortar” coating on Mg alloys. The Ca–P layer moderates corrosion and offers mineral cues, while the peptide enhances adhesion and regulates immune‐vascular responses.
Siming Zhang, Tao Zhang, Yuan Chen, Nikolaos Kourkoumelis, Mo Chen, Jiale Dong, Zhenyu Li, Yanling Zhou, Ning Li, Chen Zhu, Xifu Shang, Jiaxiang Bai, Xianzuo Zhang   +12 more
wiley   +1 more source