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Osteogenic Sarcoma with Epithelial Differentiation

Ultrastructural Pathology, 1992
This case report details an osteogenic sarcoma arising in a vertebra in which cytokeratin intermediate filaments were detected immunohistochemically with three different antibodies. This feature was present not only in the primary neoplasm but also in two local recurrences and a metastasis to the iliac bone. What is unique about this primary bone tumor,
I, Dardick, J E, Schatz, T J, Colgan
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Berberine derivative, Q8, stimulates osteogenic differentiation

Biochemical and Biophysical Research Communications, 2018
Berberine has been implicated to be involved in maintaining bone health due to its anti-oxidative and osteogenic properties. However, low potency and low bioavailability limit the clinical development of the drug. To overcome these obstacles, we previously synthesized a compound, Q8, which is a structural homolog of berberine.
Younho Han   +2 more
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Osteogenic Differentiation from Mouse Embryonic Stem Cells

2021
Embryonic stem cells (ESCs) are a unique model that allows the study of molecular pathways underlying commitment and differentiation. We have studied signaling pathways and their contributions to osteogenic differentiation. In addition to our previously published protocol where we recommended the addition of retinoic acid with later addition of ...
Zahra, Alvandi, Michal, Opas
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Osteogenic differentiation on DLC‐PDMS‐h surface

Journal of Biomedical Materials Research Part B: Applied Biomaterials, 2014
AbstractThe hypothesis was that anti‐fouling diamond‐like carbon polydimethylsiloxane hybrid (DLC‐PDMS‐h) surface impairs early and late cellular adhesion and matrix–cell interactions. The effect of hybrid surface on cellular adhesion and cytoskeletal organization, important for osteogenesis of human mesenchymal stromal cells (hMSC), where therefore ...
Kaivosoja Emilia   +11 more
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In vitro induction of osteogenic differentiation from non-osteogenic mesenchymal cells

Biomaterials, 1997
The process of ectopic bone formation suggests that extraskeletal cells are capable of osteogenesis. Alkaline phosphatase (ALP) activity is considered to be an early marker of osteogenic differentiation. This study determined whether cells from the rabbit dermis, striated muscle and extramedullary adipose tissue could undergo osteogenic differentiation
L, Lecoeur, J P, Ouhayoun
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Engineered Phage Matrix Stiffness-Modulating Osteogenic Differentiation

ACS Applied Materials & Interfaces, 2018
Herein, we demonstrate an engineered phage mediated matrix for osteogenic differentiation with controlled stiffness by cross-linking the engineered phage displaying Arg-Gly-Asp (RGD) and His-Pro-Gln (HPQ) with various concentrations of streptavidin or polymer, poly(diallyldimethylammonium)chloride (PDDA).
Hee-Sook Lee   +6 more
openaire   +2 more sources

Osteogenic Differentiation from Embryonic Stem Cells

2014
Embryonic stem (ES) cells have been widely studied due to their pluripotency and their potential of self-renewal. Murine ES cells are useful in investigating the molecular pathways underlying their differentiation to various mature cell types in the body.
Yanhong, Yu   +2 more
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