Results 131 to 140 of about 2,318 (174)
Senescent immune cells, inflammaging, and bone loss: therapeutic potential and translational challenges of senolytics in osteoporosis. [PDF]
Front Endocrinol (Lausanne)Zhu M +7 more
europepmc +1 more source
Role of the S1P/S1PR axis in inflammation and structural damage in psoriatic arthritis: a cross-sectional study with clinical, biochemical and imaging correlation. [PDF]
RMD OpenRuiz-Montesinos D +10 more
europepmc +1 more source
Identification of candidate immunity biomarkers associated with age-related variations in osteoclast activity in a mouse model of orthodontic tooth movement. [PDF]
BMC Oral HealthZhang R +5 more
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Osteoimmunology of Spondyloarthritis
International Journal of Molecular Sciences, 2023 The mechanisms underlying the development of bone damage in the context of spondyloarthritis (SpA) are not completely understood. To date, a considerable amount of evidence indicates that several developmental pathways are crucially involved in osteoimmunology.
Chiara Crotti +2 more
exaly +5 more sources
Osteoimmunology and Beyond [PDF]
Current Medicinal Chemistry, 2016 Osteoimmunology investigates interactions between skeleton and immune system. In the light of recent discoveries in this field, a new reading register of osteoporosis is actually emerging, in which bone and immune cells are strictly interconnected. Osteoporosis could therefore be considered a chronic immune mediated disease which shares with other age ...
Lia Ginaldi, Massimo De Martinis
exaly +4 more sources
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Alcoholism and Osteoimmunology
Current Medicinal Chemistry, 2021Background :Chronic consumption of alcohol has an adverse effect on the skeletal system, which may lead to osteoporosis, delayed fracture healing and osteonecrosis of the femoral head. Currently, the treatment is limited, therefore, there is an urgent need to determine the underline mechanism and develop a new treatment.
Xiuwen Wang +3 more
openaire +2 more sources
Calcified Tissue International, 2018
Aberrant or prolonged immune responses often affect bone metabolism. The investigation on bone destruction observed in autoimmune arthritis contributed to the development of research area on effect of the immune system on bone. A number of reports on bone phenotypes of immunocompromised mice indicate that the immune and skeletal systems share various ...
Asuka, Terashima, Hiroshi, Takayanagi
openaire +2 more sources
Aberrant or prolonged immune responses often affect bone metabolism. The investigation on bone destruction observed in autoimmune arthritis contributed to the development of research area on effect of the immune system on bone. A number of reports on bone phenotypes of immunocompromised mice indicate that the immune and skeletal systems share various ...
Asuka, Terashima, Hiroshi, Takayanagi
openaire +2 more sources
New developments in osteoimmunology
Nature Reviews Rheumatology, 2012Investigations into interactions between the skeletal and immune systems were developed during research into arthritis, with characterization of T-cell-mediated regulation of osteoclastogenesis. A new interdisciplinary field--osteoimmunology--was created, and has since expanded to encompass disciplines including signal transduction, stem cell niches ...
Hiroshi Takayanagi
exaly +3 more sources
RANKL and osteoimmunology in periodontitis
Journal of Bone and Mineral Metabolism, 2020Periodontitis, one of the most common infectious diseases in humans, is characterized by inflammation of the periodontal tissue and subsequent destruction of the alveolar bone, which ultimately leads to tooth loss. Recently, it was revealed that the osteoclastic bone damage that occurs during periodontitis is dependent on the receptor activator of NF ...
openaire +2 more sources