Results 1 to 10 of about 9,317 (202)

Role of dendritic cells in MYD88-mediated immune recognition and osteoinduction initiated by the implantation of biomaterials

International Journal of Oral Science, 2023
Bone substitute material implantation has become an important treatment strategy for the repair of oral and maxillofacial bone defects. Recent studies have shown that appropriate inflammatory and immune cells are essential factors in the process of ...
Zifan Zhao, Qin Zhao, Hu Chen, Fanfan Chen, Feifei Wang, Hua Tang, Haibin Xia, Yongsheng Zhou, Yuchun Sun   +8 more
doaj   +3 more sources

Honeycomb scaffolds capable of ectopic osteogenesis: Histological evaluation of osteoinduction mechanism

Nano Select, 2022
Scaffolds capable of inducing ectopic osteogenesis (i.e., osteoinduction) have the potential to treat congenital and massive bone defects. However, the mechanisms underlying osteoinduction remain elusive, largely because of rapid tissue changes occurring
Koichiro Hayashi
exaly   +2 more sources

Bone Grafts: Everything You Need to Know. [PDF]

J Periodontal Res
This review classifies bone grafts (autograft, allograft, xenograft, synthetic) by source and osteogenic/inductive/conductive potential, linking material properties and mechanisms to clinical indications in periodontal and dental regeneration. Key challenges—limited osteoinduction, poor vascularisation, unbalanced resorption, handling difficulties, and
Haugen HJ, Sanz J, Perale G, Saiz AM, Romandini M, Rahmati M.   +5 more
europepmc   +2 more sources

Bamboo-Like Whiskers-Reinforced Bioceramics Accelerate Large Segmental Bone Regeneration via Dual Modulation of Type-H Vessels and Osteoinduction. [PDF]

Adv Sci (Weinh)
The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Feng C, Teng H, Xu C, He J, Liu K, Li X, Zhang K, Zhu X, Li X, Xu J, Zhang X.   +10 more
europepmc   +2 more sources

Exercise Promotes the Osteoinduction of HA/β-TCP Biomaterials via the Wnt Signaling Pathway

Metabolites, 2020
To investigate the osteoinductive mechanism triggered by hydroxyapatite/β-tricalcium phosphate (HA/β-TCP) biomaterials in mice which keep exercising.
Zheng Shi, Liang Zou
exaly   +3 more sources

Bone Morphogenetic Proteins-2–Augmented Acetabular Bone Stock Restoration During Two-stage Revision for Periprosthetic Joint Infection: A Case Report [PDF]

Journal of Orthopaedic Case Reports
Introduction: Severe acetabular bone loss in the setting of Periprosthetic Joint Infection (PJI) presents a significant reconstructive challenge, particularly in biologically compromised environments where conventional graft incorporation may be ...
Vaibhav Bagaria, Shobit Deshmukh, Anjali Tiwari   +2 more
doaj   +2 more sources

Osteo-Inductive Strategies for Enhancing Osseointegration and Optimizing Peri-Implant Emergence Profile: A Narrative Review [PDF]

Dentistry Journal
Background: Osteoinduction and bone regeneration are fundamental biological mechanisms enabling osseointegration and long-term durability of endosseous dental implants.
Ioan Sirbu, Elisei Adelin Radu, Andy Radu Leibovici, Andreea Mihaela Custura, Ruxandra Stanescu, Alexandra Tuta, Vladimir Nastasie, Valentin Daniel Sirbu   +7 more
doaj   +2 more sources

Chitosan/Hydroxyapatite Scaffolds with P28 as a Promising Osteoinductive Scaffold for Bone Healing Applications

Micro, 2023
Despite bone’s inherent ability to heal, large bone defects remain a major clinical concern. This study proposes an off-the-shelf treatment combining chitosan/hydroxyapatite (CS/HAp) scaffolds, covalently linked with either bone morphogenetic protein-2 ...
Farah Alwani Azaman, Florence Daubiné, Amélie Lebatard, Margaret E. Brennan Fournet, Declan M. Devine   +4 more
doaj   +1 more source

Influence of the Degree of Deacetylation of Chitosan and BMP-2 Concentration on Biocompatibility and Osteogenic Properties of BMP-2/PLA Granule-Loaded Chitosan/β-Glycerophosphate Hydrogels

Molecules, 2021
Compositions based on chitosan/β-glycerophosphate hydrogels with highly porous polylactide granules can be used to obtain moldable bone graft materials that have osteoinductive and osteoconductive properties.
Andrey Vyacheslavovich Vasilyev, Valeriya Sergeevna Kuznetsova, Tatyana Borisovna Bukharova, Timofei Evgenevich Grigoriev, Yuriy Dmitrievich Zagoskin, Irina Alekseevna Nedorubova, Igor Ivanovich Babichenko, Sergey Nicolaevich Chvalun, Dmitry Vadimovich Goldstein, Anatoliy Alekseevich Kulakov   +9 more
doaj   +1 more source

Modern osteoplastic materials

RUDN Journal of Medicine, 2023
Relevance. Bone tissue regeneration and the development of methods for directed influence on the processes of bone healing are of the most urgent problems of modern medicine.
Karina M. Salekh, Alexandr B. Dymnikov, Roman F. Mukhametshin, Sergey G. Ivashkevich   +3 more
doaj   +1 more source