Results 31 to 40 of about 5,237 (179)

Optimisation of BMP-2 dosage for the osseointegration of porous titanium implants in an ovine model [PDF]

open access: yesEuropean Cells & Materials, 2016
In clinical orthopaedics, total joint replacements and spinal fusions are routine undertakings. Many of the implicated patients suffer from osteoporosis, severe arthrosis or osteopaenia.
EB Hunziker   +5 more
doaj   +1 more source

Anodic TiO2 Nanotubes: Tailoring Osteoinduction via Drug Delivery

open access: yesNanomaterials, 2021
TiO2 nanostructures and more specifically nanotubes have gained significant attention in biomedical applications, due to their controlled nanoscale topography in the sub-100 nm range, high surface area, chemical resistance, and biocompatibility.
Jung Park   +3 more
doaj   +1 more source

Advances in Antimicrobial and Osteoinductive Biomaterials

open access: yes, 2020
The enormous growing problem with antibiotic resistance in pathogenic microbes is one of the greatest threats we are facing today. In the context of orthopedic applications, infections also lead to the limited healing ability of infected and defected bone.
Afewerki, Samson   +7 more
openaire   +3 more sources

Comparison of different hydroxyapatite composites for bone tissue repair: In vitro and in vivo analyses [PDF]

open access: yesIranian Journal of Basic Medical Sciences
Objective(s): The material used for bone tissue repair needs to be simultaneously osteoconductive, osteoinductive, and osteogenic. To overcome this problem, researchers combine hydroxyapatite (HA) with natural materials to improve properties.
Xiaoyu Su   +7 more
doaj   +1 more source

Low Dose BMP2-Doped Calcium Phosphate Graft Promotes Bone Defect Healing in a Large Animal Model

open access: yesFrontiers in Cell and Developmental Biology, 2021
Background: Bone grafts are in high demand due to the increase in the cases of bone defects mainly caused by trauma, old age, and disease-related bone damages.
Tie Liu   +8 more
doaj   +1 more source

Morphological features of bone tissue regenerates in experimental animals when using osteotropic drugs for recovery bone defects

open access: yesJournal of Education, Health and Sport, 2021
The aim of the study was to determine the effectiveness using of osteotropic drugs for the restoration of bone defects. Materials and methods. The model experiment was performing on male Wistar rats.
Yulia Lysokon   +2 more
doaj   +1 more source

VREDEN RUSSIAN RESEARCH INSTITUTE OF TRAUMATOLOGY AND ORTHOPEDICS

open access: yesTravmatologiâ i Ortopediâ Rossii, 2017
Currently, the use of bone allografts for reconstructive orthopedic surgery in clinical practice around the world is becoming a common procedure. Bone allografts are the first substitute material to the autologous bone and the best alternative to any ...
K. A. Vorobyоv   +3 more
doaj   +1 more source

Engineering Approaches to Modify Immunomodulatory Functions of Mesenchymal Stromal Cells (MSCs): Tissue Regeneration and Clinical Application

open access: yesAdvanced Science, EarlyView.
Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang   +6 more
wiley   +1 more source

Clinical and radiographic evaluation of demineralized bone matrix (grafton) as a bone graft material in the treatment of human periodontal intraosseous defects

open access: yesJournal of Indian Society of Periodontology, 2013
Purpose: The purpose of this clinical trial was to evaluate the efficacy of demineralized bone matrix (DBM) as a bone graft material in the treatment of human intrabony periodontal defects as compared with control defects treated by open flap debridement
Mahantesha   +5 more
doaj   +1 more source

Bamboo‐Like Whiskers‐Reinforced Bioceramics Accelerate Large Segmental Bone Regeneration via Dual Modulation of Type‐H Vessels and Osteoinduction

open access: yesAdvanced Science, EarlyView.
The graphical abstract image of bamboo‐like whisker‐reinforced Ca‐P bioceramics accelerating large segmental bone regeneration. ABSTRACT Regenerative repair of segmental bone defect remains a major clinical challenge. The conventional mental implants suffer from mechanical strength mismatch and long‐term foreign bodies presence.
Cong Feng   +10 more
wiley   +1 more source

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