Results 41 to 50 of about 5,194 (135)

Camouflaged angiogenic BMP-2 functions exposed by pico-paracrine biohybrids

Frontiers in Bioengineering and Biotechnology, 2023
The constant release of human bone morphogenetic protein 2 (rhBMP-2) in the picomolar range (Pico-Stat) from PDLLA-biohybrids led to the detection of intrinsic novel pro- and anti-angiogenic functions of this cytokine.
Herbert P. Jennissen
doaj   +1 more source

Repositioning Titanium: An In Vitro Evaluation of Laser-Generated Microporous, Microrough Titanium Templates As a Potential Bridging Interface for Enhanced Osseointegration and Durability of Implants

Frontiers in Bioengineering and Biotechnology, 2017
Although titanium alloys remain the preferred biomaterials for the manufacture of biomedical implants today, such devices can fail within 15 years of implantation due to inadequate osseointegration.
Daniel Tang, Liang-Yo Yang, Liang-Yo Yang, Liang-Yo Yang, Keng-Liang Ou, Keng-Liang Ou, Keng-Liang Ou, Keng-Liang Ou, Richard O. C. Oreffo   +8 more
doaj   +1 more source

Next Generation Smart Implant Surfaces: Engineering Multifunctional Antimicrobial, Immunomodulatory and Regenerative Interfaces

Journal of Periodontal Research, EarlyView.
Natural‐inspired nano‐textured implant surfaces can be functionalised to modulate macrophage polarisation and local immune responses. This bioactive control promotes improved tissue integration and healing outcomes. ABSTRACT Dental implants rely on a stable and functional interface between the implant surface, surrounding tissues, and the oral ...
Roberto S. Pessoa, Lauren E. Steele, Mehvish Mumtaz, Denver P. Linklater, Neil M. O'Brien‐Simpson, Vladimir Baulin, Peter Kingshott, Roy Judge, Alastair J. Sloan, Elena P. Ivanova   +9 more
wiley   +1 more source

Nanomaterial Nitric Oxide Delivery in Traumatic Orthopedic Regenerative Medicine

Frontiers in Bioengineering and Biotechnology, 2021
Achieving bone fracture union after trauma represents a major challenge for the orthopedic surgeon. Fracture non-healing has a multifactorial etiology and there are many risk factors for non-fusion.
Albert Thomas Anastasio, Ariana Paniagua, Carrie Diamond, Harrison R. Ferlauto, Joseph S. Fernandez-Moure   +4 more
doaj   +1 more source

Long‐term stability of horizontal bone augmentation at implant sites

Periodontology 2000, EarlyView.
Abstract Horizontal bone augmentation is a fundamental surgical procedure in regenerative implant dentistry. In recent decades, this procedure has evolved, enabling clinicians to achieve predictable and stable horizontal bone augmentation that supports dental implant restorations.
Jia‐Hui Fu, Hui Jia Sophia Choo, Ding‐Sen Ong, Henry Kwek   +3 more
wiley   +1 more source

Expression of VEGF, BMP-2, and the OPG/RANK axis as indicators of osseointegration: a comparative clinical and experimental study of titanium implants with functional protective coatings

Medičnì Perspektivi
The objective of the present study was to validate key mole­cular markers of bone tissue repair as indicators of osseointegration on systemic and local levels, and evaluate their trans­lational parallelism.
O.O. Bondarenko, A.E. Lievykh, N.S. Bondarenko, A.G. Bozhko, O.Ye. Loskutov, I.S. Shponka   +5 more
doaj   +1 more source

Considerações sobre a obtenção e o uso do plasma rico em plaquetas e das células mesenquimais indiferenciadas em enxertos ósseos Isolation and use of platelet rich plasma and indiferenciate mesenchimal cells in bone grafts

Ciência Rural, 2007
O plasma rico em plaquetas (PRP) e as células mesenquimais indiferenciadas (CMIs), também chamadas de células-tronco, têm sido amplamente estudados por seus potenciais altos de osteoindução em enxertos ósseos.
Geane Maciel Pagliosa, Geraldo Eleno Silveira Alves   +1 more
doaj   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Estudo da interação polímero/cartilagem/osso utilizando poli (ácido lático-co-ácido glicólico) e poli (p-dioxanona) em condilo femural de coelhos Study of polymer/cartilage/bone interaction using poly(lactic acid-co-glycolic acid) and poly (p-dioxanona) in femoral condyle of rabbits

Polímeros, 2004
Os dispositivos biorreabsorvíveis são alternativas para fixação interna das fraturas. Durante o tratamento estes dispositivos mantêm a fixação e degradam-se gradualmente não necessitando de uma cirurgia de remoção, reduzindo o custo de tratamento quando ...
Maisa M. Sakata, Maria do Carmo Alberto-Rincon, Eliana A. R. Duek   +2 more
doaj   +1 more source

Injectable Bone Cements: A Generational Framework for Bioactivity, Porosity, and Mechanobiological Design at the Nanoscale

Advanced NanoBiomed Research, Volume 6, Issue 8, August 2026.
Key demographic, biological, and material considerations that drive the need for advanced injectable bone cement technologies. Injectable bone cements (IBCs) are widely used in orthopaedic and craniofacial applications due to their minimally invasive delivery and ability to provide early mechanical stabilisation.
Frank Fei, Yogambha Ramaswamy, Young Jung No   +2 more
wiley   +1 more source