VREDEN RUSSIAN RESEARCH INSTITUTE OF TRAUMATOLOGY AND ORTHOPEDICS
Currently, the use of bone allografts for reconstructive orthopedic surgery in clinical practice around the world is becoming a common procedure. Bone allografts are the first substitute material to the autologous bone and the best alternative to any ...
K. A. Vorobyоv +3 more
doaj +1 more source
The aim of the study was to determine the effectiveness using of osteotropic drugs for the restoration of bone defects. Materials and methods. The model experiment was performing on male Wistar rats.
Yulia Lysokon +2 more
doaj +1 more source
Neurovascular coupling in bone regeneration: Mechanisms, advanced biomaterials and challenges
This figure illustrates various material strategies for neurovascularized bone regeneration, including electroactive scaffolds, ion‐loaded materials, drug delivery systems, surface modifications, cells/cell products, growth factors, and peptides. These approaches aim to synergistically promote the regeneration of neural, vascular, and bone tissues ...
Yixin Ma +8 more
wiley +1 more source
Gradual increase in alkaline phosphatase and osteocalcin post-osteoinduction.
(A) Alkaline phosphatase staining in hASC. (B) Alkaline phosphatase staining in osteoblasts cultured for 16 days with osteoinduction medium. (C) Level of alkaline phosphatase. (D) Level of osteocalcin.
Willian F. Zambuzzi (127932) +16 more
core +1 more source
Purpose: The purpose of this clinical trial was to evaluate the efficacy of demineralized bone matrix (DBM) as a bone graft material in the treatment of human intrabony periodontal defects as compared with control defects treated by open flap debridement
Mahantesha +5 more
doaj +1 more source
Progress in bone tissue engineering biomaterials: Development, challenges, and prospects
Scheme 1 Application of biomaterials in immunomodulation during bone tissue engineering. Abstract Bone defect repair remains a major clinical challenge in orthopedics. Over 2 million cases caused by trauma, tumors, and other factors occur annually, with large‐scale defects posing a particular bottleneck due to limited self‐healing capacity.
Yuanbin Zhang +7 more
wiley +1 more source
Osteoinduction within adipose tissue fragments by heterodimeric bone morphogenetic Proteins‐2/6 and ‐2/7 versus homodimeric bone morphogenetic protein‐2: Therapeutic implications for bone regeneration [PDF]
Background Fragments of subcutaneous adipose tissue that have been genetically modified to express bone morphogenetic protein‐2 (BMP‐2) regenerate large segmental osseous lesions in rodents.
Oliver B. Betz +9 more
core +1 more source
Osteoinduction Ability of Human Adipose-Derived Mesenchymal Stem Cell with Chitosan Scaffold Combination Towards Blood Serum Phosphorus Levels [PDF]
ologous tissue can cause problems in the repair of extensive tissue damage, so the principle of tissue engineering is used as an alternative to reconstruct damage to the tissue because it has many advantages.
Nindya R A Marhendra, - +10 more
core +1 more source
Functional assay, expression of growth factors and proteins modulating bone-arrangement in human osteoblasts seeded on an anorganic bovine bone biomaterial [PDF]
The basic aspects of bone tissue engineering include chemical composition and geometry of the scaffold design, because it is very important to improve not only cell attachment and growth but especially osteodifferentiation, bone tissue formation, and ...
O Trubiani +7 more
doaj
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag +6 more
wiley +1 more source

