Results 51 to 60 of about 5,237 (179)

Repositioning Titanium: An In Vitro Evaluation of Laser-Generated Microporous, Microrough Titanium Templates As a Potential Bridging Interface for Enhanced Osseointegration and Durability of Implants

Frontiers in Bioengineering and Biotechnology, 2017
Although titanium alloys remain the preferred biomaterials for the manufacture of biomedical implants today, such devices can fail within 15 years of implantation due to inadequate osseointegration.
Daniel Tang, Liang-Yo Yang, Liang-Yo Yang, Liang-Yo Yang, Keng-Liang Ou, Keng-Liang Ou, Keng-Liang Ou, Keng-Liang Ou, Richard O. C. Oreffo   +8 more
doaj   +1 more source

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

Journal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag, Magdalena Mayol, Danijel Domic, Madhusudhan Reddy Bobbili, Johannes Grillari, Mariano Sanz, Reinhard Gruber   +6 more
wiley   +1 more source

A Multifunctional β‐Defensin‐3 Mimetic Peptide Modulates Host–Biofilm Interactions and Reduces Bone Loss in Periodontitis

Journal of Periodontal Research, EarlyView.
BDMP, a peptide that can penetrate cells and tissues, offering antimicrobial and anti‐inflammatory effects, has been identified as a potential new therapy for periodontitis. ABSTRACT Aim This study evaluated the potential of a beta‐defensin‐3 mimetic peptide (BDMP), a synthetic cell‐penetrating peptide with antimicrobial and immunomodulatory properties,
Beom Soo Jo, Dong Woo Lee, Ji‐Young Lee, Sanghui Seok, Yu‐Bin Kim, Jue‐Yeon Lee, Shin‐Young Park, Young Dan Cho, Yang Jo Seol, Yoon Shin Park, Shahram Ghanaati, Homayoun H. Zadeh, Chong Pyung Chung, Yoon Jeong Park   +13 more
wiley   +1 more source

Considerações sobre a obtenção e o uso do plasma rico em plaquetas e das células mesenquimais indiferenciadas em enxertos ósseos Isolation and use of platelet rich plasma and indiferenciate mesenchimal cells in bone grafts

Ciência Rural, 2007
O plasma rico em plaquetas (PRP) e as células mesenquimais indiferenciadas (CMIs), também chamadas de células-tronco, têm sido amplamente estudados por seus potenciais altos de osteoindução em enxertos ósseos.
Geane Maciel Pagliosa, Geraldo Eleno Silveira Alves   +1 more
doaj   +1 more source

Valuation of angiogenesis in bovine xenografts implanted in intracorporal sites of rabbits as models of in-vivo bioreactors

Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 2021
The aim of this study was to evaluate neovascularization of bovine xenografts implanted in intracorporeal sites of rabbits (bioreactors). 30 rabbits were used, divided into 6 groups, according to the evaluation time (7, 15, 30, 45, and 60 days); each ...
G.L. Montanhim, M.T.S. Silva, M.E.B.A.M. Conceição, T.S. Rocha, L.M. Yamashiro, J.O. Ribeiro, A. Hataka, P.R.R. Moreira, B.W. Minto, L.G.G.G. Dias, P.C. Moraes   +10 more
doaj   +1 more source

Expression of VEGF, BMP-2, and the OPG/RANK axis as indicators of osseointegration: a comparative clinical and experimental study of titanium implants with functional protective coatings

Medičnì Perspektivi
The objective of the present study was to validate key mole­cular markers of bone tissue repair as indicators of osseointegration on systemic and local levels, and evaluate their trans­lational parallelism.
O.O. Bondarenko, A.E. Lievykh, N.S. Bondarenko, A.G. Bozhko, O.Ye. Loskutov, I.S. Shponka   +5 more
doaj   +1 more source

Estudo da interação polímero/cartilagem/osso utilizando poli (ácido lático-co-ácido glicólico) e poli (p-dioxanona) em condilo femural de coelhos Study of polymer/cartilage/bone interaction using poly(lactic acid-co-glycolic acid) and poly (p-dioxanona) in femoral condyle of rabbits

Polímeros, 2004
Os dispositivos biorreabsorvíveis são alternativas para fixação interna das fraturas. Durante o tratamento estes dispositivos mantêm a fixação e degradam-se gradualmente não necessitando de uma cirurgia de remoção, reduzindo o custo de tratamento quando ...
Maisa M. Sakata, Maria do Carmo Alberto-Rincon, Eliana A. R. Duek   +2 more
doaj   +1 more source

Long‐term stability of horizontal bone augmentation at implant sites

Periodontology 2000, EarlyView.
Abstract Horizontal bone augmentation is a fundamental surgical procedure in regenerative implant dentistry. In recent decades, this procedure has evolved, enabling clinicians to achieve predictable and stable horizontal bone augmentation that supports dental implant restorations.
Jia‐Hui Fu, Hui Jia Sophia Choo, Ding‐Sen Ong, Henry Kwek   +3 more
wiley   +1 more source

Understanding exosomes in regenerative dentistry

Periodontology 2000, EarlyView.
Abstract Background Regenerative dentistry is shifting from cell‐based strategies to cell‐free biologics capable of orchestrating intricate tissue repair. Exosomes, nanosized extracellular vesicles carrying bioactive molecular payloads, have emerged as central modulators of intercellular communication.
Paras Ahmad, Anton Sculean, Richard J. Miron   +2 more
wiley   +1 more source

Biodegradable Natural Polymer‐Based Drug Delivery Systems for Bone Tissue Engineering

Medicinal Research Reviews, Volume 46, Issue 4, Page 966-988, July 2026.
ABSTRACT The increasing incidence of bone diseases and injuries, especially among aging populations, has underscored the shortcomings of traditional treatments such as bone grafts and metal implants, which often face complications including immune rejection, mechanical failure, and delayed healing.
Hyejin Jo, Shinwon Kang, Jae Eun Yang, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source